RESUMEN
In the present study, we report the occurrence of Lyme's borreliosis in patients from the Brazilian Amazon Region. Borreliosis was investigated by immunohistochemistry and focus floating microscopy for Borrelia burgdorferi in skin biopsy samples from 22 patients with both clinical and histopathology evidences compatible with Erythema Migrans. Spirochetes were detected by specific immunohistochemistry and focus floating microscopy for B. burgdorferi in samples from five patients. Clinical cure of the cutaneous lesions was observed in all the patients after treatment with doxycycline regimen as proposed by the Center Disease Control guidelines. A limitation of our study was the fact that we were not able to isolate and culture these organisms. These are the first known Brazilian cases of borreliosis to have Focus Floating Microscopy confirmation.
Asunto(s)
Grupo Borrelia Burgdorferi/aislamiento & purificación , Enfermedad de Lyme/diagnóstico , Piel/microbiología , Adulto , Antibacterianos/uso terapéutico , Biopsia , Grupo Borrelia Burgdorferi/citología , Brasil/epidemiología , Doxiciclina/uso terapéutico , Femenino , Humanos , Inmunohistoquímica , Enfermedad de Lyme/tratamiento farmacológico , Enfermedad de Lyme/microbiología , Masculino , Microscopía , Persona de Mediana Edad , Piel/patología , Resultado del TratamientoRESUMEN
Lobomycosis, also known as Jorge Lobo's disease, is a granulomatous, chronic fungal disease that involves the skin and subcutaneous tissue. The disease has been reported in South American, Central and North American countries, being particularly frequent in the Brazilian Amazon region. We report a case of disseminated lobomycosis in an 86 year-old Brazilian woman with a 55-year history of disseminated cutaneous lesions.