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1.
Data Brief ; 55: 110722, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-39109168

RESUMEN

The dataset presented in this article is an update of the dataset provided by K. Edanami and G. Sun entitled "Medical Radar Signal Dataset for Non-Contact Respiration and Heart Rate Measurement" [1]. The new dataset includes radar signals and reference laser measurements from experiments conducted on anesthetized rats. The rats were placed in a prone position, and isoflurane was administered in varying concentrations to maintain anesthesia. A 24 GHz radar and laser sensor were positioned above the rats to capture the necessary data. The dataset contains time-stamped radar I and Q channel signals as well as laser measurements. Additionally, MATLAB code for signal visualization and FFT (fast Fourier transform)-based respiration rate estimation is provided. This comprehensive dataset and accompanying MATLAB code facilitate the advancement of non-invasive respiration measurement techniques in small animals, with potential applications in biomedical research.

2.
Virol J ; 21(1): 172, 2024 Aug 02.
Artículo en Inglés | MEDLINE | ID: mdl-39095779

RESUMEN

Human papillomavirus (HPV) 11/16 E6/E7 proteins have been recognized to be pivotal in viral pathogenesis. This study sought to uncover the potential mechanisms of how HPV11/16 E6/E7-transfected keratinocytes inhibit cytokine secretion in peripheral blood mononuclear cells (PBMC). Upon co-culturing HPV11/16 E6/E7-transfected keratinocytes with PBMC in a non-contact manner, we observed a marked decrease in various cytokines secreted by PBMC. To determine if this suppression was mediated by specific common secreted factors, we conducted transcriptomic sequencing on these transfected cells. This analysis identified 53 common differentially secreted genes in all four HPV-transfected cells. Bioinformatics analysis demonstrated these genes were predominantly involved in immune regulation. Results from quantitative PCR (qPCR) and an extensive literature review suggested the downregulation of 12 genes (ACE2, BMP3, BPIFB1, CLU, CST6, CTF1, HMGB2, MMP12, PDGFA, RNASE7, SULF2, TGM2), and upregulation of 7 genes (CCL17, CCL22, FBLN1, PLAU, S100A7, S100A8, S100A9), may be crucial in modulating tumor immunity and combating pathogenic infections, with genes S100A8 and S100A9, and IL-17 signaling pathway being particularly noteworthy. Thus, HPV11/16 E6/E7 proteins may inhibit cytokine secretion of immune cells by altering the expression of host-secreted genes. Further exploration of these genes may yield new insights into the complex dynamics of HPV infection.


Asunto(s)
Citocinas , Leucocitos Mononucleares , Proteínas Oncogénicas Virales , Humanos , Citocinas/metabolismo , Citocinas/genética , Leucocitos Mononucleares/inmunología , Leucocitos Mononucleares/virología , Leucocitos Mononucleares/metabolismo , Proteínas Oncogénicas Virales/genética , Proteínas Oncogénicas Virales/metabolismo , Proteínas Oncogénicas Virales/inmunología , Queratinocitos/virología , Queratinocitos/inmunología , Queratinocitos/metabolismo , Papillomavirus Humano 16/genética , Papillomavirus Humano 16/inmunología , Papillomavirus Humano 11/genética , Papillomavirus Humano 11/inmunología , Perfilación de la Expresión Génica , Infecciones por Papillomavirus/virología , Infecciones por Papillomavirus/inmunología , Infecciones por Papillomavirus/genética , Proteínas E7 de Papillomavirus/genética , Proteínas E7 de Papillomavirus/metabolismo , Proteínas E7 de Papillomavirus/inmunología , Técnicas de Cocultivo , Interacciones Huésped-Patógeno/inmunología , Interacciones Huésped-Patógeno/genética
3.
Clin Exp Optom ; : 1-6, 2024 Jul 07.
Artículo en Inglés | MEDLINE | ID: mdl-38972001

RESUMEN

CLINICAL RELEVANCE: Understanding the causes of visual symptoms in epilepsy patients is important for early diagnosis and taking precautions. BACKGROUND: The aim of this study is to evaluate the anterior and posterior segment parameters in patients with generalized tonic-clonic epilepsy (GTCE). METHODS: This retrospective study included 50 eyes of 50 patients with GTCE and 55 eyes of 55 healthy controls. For all participants, detailed ophthalmic examinations were obtained from the files of patients. Anterior segment parameters were measured using corneal topography and non-contact specular microscopy, and posterior segment parameters were measured using swept-source optical coherence tomography. RESULTS: The mean age of the patients with GTCE was 43.3 ± 13.2 years, and in the healthy controls it was 47.6 ± 10.7 years (p = 0.405). In GTCE patients, 34 patients were treated with monotherapy (MT) and 16 patients with polytherapy (PT). Central macular thickness (CMT) was statistically significantly thin in GTCE patients (p = 0.001). The average and four quadrants (superior, inferior, nasal, temporal) retinal nerve fibre layer (RNFL) were thinner in GTCE patients than in the healthy controls, but there was no statistically significant difference (p > 0.05, all). The central corneal thickness was statistically significantly thin in GTCE patients (p = 0.04). Endothelial cell density (ECD), endothelial cell number (ECN), and average cell area (ACA) were statistically significantly lower in GTCE patients than in the healthy controls (p < 0.05, all). Although the CMT, average, and four-quadrants RNFL were thinner in the PT group compared to the MT group, no statistically significant difference was observed (p > 0.05, all). Total high-order aberrations (HOAs) were 0.6 ± 0.4 in the MT group and 0.4 ± 0.1 in the PT group (p = 0.01). ECD, ECN, and ACA measurements were observed to be lower in the PT group compared to the MT group, but no statistically significant difference was detected (p > 0.05, all). CONCLUSION: There could be statistically significant differences between GTCE patients and healthy controls in anterior and posterior segment parameters. This situation may be due to the epilepsy itself or to the antiepileptic drugs.

4.
Eur J Ophthalmol ; : 11206721241263624, 2024 Jul 26.
Artículo en Inglés | MEDLINE | ID: mdl-39056138

RESUMEN

PURPOSE: To evaluate the diagnostic validity of the HNT-1P non-contact tonometer (Huvitz) as a tool for accurately measuring intraocular pressure (IOP) in patients with healthy eyes, compared to the Goldmann applanation tonometer (GAT), which is the Gold Standard method for measurement of IOP. METHODS: Observational, descriptive, transversal study using 148 eyes of 74 healthy patients without a diagnosis of glaucoma or other ophthalmological diseases. Three measurements of IOP were taken in each eye, using three tonometers: HNT-1P, ICR100, and GAT. The median IOP (quartiles) and mean IOP (SD) its statistical significance were calculated, and comparisons were made between the mean and median IOP values found in three groups: GAT-HNT, GAT-ICR, and HNT-ICR. The difference in mean and median IOP was analyzed in each of the three study groups, and its statistical significance and concordance correlation coefficient (CCC) were calculated. RESULTS: The median IOP with HNT-1P was statistically significantly lower than the median IOP with GAT, (1.1 mmHg, p < 0.001). The median IOP with HNT-1P was also lower than the median IOP with ICR100. As an additional result, the median IOP with GAT was lower than the median IOP with ICR. The CCC was moderate for HNT-ICR (0.72) and low for GAT-HNT and GAT-ICR (0.43 and 0.38, respectively). CONCLUSIONS: HNT-1P (Huvitz) provides statistically significantly lower IOP values than those obtained with GAT. HNT-1P could be used for screening of ocular hypertension in postoperative patients. The IOP measurement obtained with HNT-1P should be confirmed with GAT. HNT-1P yields lower IOP values than those obtained with ICR.

5.
Foods ; 13(14)2024 Jul 16.
Artículo en Inglés | MEDLINE | ID: mdl-39063328

RESUMEN

Agricultural food commodities are highly susceptible to contamination by fungi and mycotoxins, which cause great economic losses and threaten public health. New technologies such as gamma ray irradiation, ultraviolet radiation, electron beam irradiation, microwave irradiation, pulsed light, pulsed electric fields, plasma, ozone, etc. can solve the problem of fungal and mycotoxin contamination which cannot be effectively solved by traditional food processing methods. This paper summarizes recent advancements in emerging food decontamination technologies used to control various fungi and their associated toxin contamination in food. It discusses the problems and challenges faced by the various methods currently used to control mycotoxins, looks forward to the new trends in the development of mycotoxin degradation methods in the future food industry, and proposes new research directions.

6.
Sci Rep ; 14(1): 17514, 2024 Jul 30.
Artículo en Inglés | MEDLINE | ID: mdl-39079953

RESUMEN

To investigate the extent of damage and seepage characteristics of water-saturated coal samples after subjecting them to microwave cycling. The microwave equipment was used to process the coal samples by microwave cycling. The non-contact digital image processing technology and acoustic emission system were used to carry out the triaxial loading experimental study of the coal samples to obtain the mechanical parameter characteristics, energy evolution pattern, acoustic emission information and permeability characteristics of coal samples under different microwave cycle times. The results of the study show that: With the increase in the number of microwave cycles, dense grid-loaded cracks gradually appeared on the surface of the coal samples, the triaxial partial stresses of the coal samples decreased, and the strains also decreased, and the modulus of elasticity and Poisson's ratio also decreased; In the densification stage stage, the dissipated energy is higher than the elastic energy, and as the elastic stage proceeds, the elastic energy gradually reverses to exceed the dissipated energy, and the total energy and elastic energy of the coal samples decrease with the increase in the number of cycles, and the dissipated energy rises; Coal samples produce a large number of fissures due to the increase in the number of microwave cycles, the more frequent the fissure activity during the loading process, the acoustic emission amplitude and ringing count scattering points all become dense with the increase in the number of cycles, and the data increase; Initial permeability, destructive permeability and average permeability were all increased, microwave treatment has a better effect of permeability enhancement, the permeability of the treated coal samples was changed from low permeability to medium permeability, and the permeability enhancement was the largest in 6 cycles, and the permeability was increased by 7.18 times. This article explores the damage condition of water-saturated coal samples under microwave cycling treatment. Then, it explores the effect of microwave cycling on the permeability enhancement of the coal body, which provides a new method for exploring the gas permeability enhancement and extraction of low-permeability coal samples underground.

7.
Nano Lett ; 2024 Jul 22.
Artículo en Inglés | MEDLINE | ID: mdl-39038223

RESUMEN

This study delves into the intriguing properties of the 1H/1T-TaS2 van der Waals heterostructure, focusing on the transparency of the 1H layer to the charge density wave of the underlying 1T layer. Despite the sizable interlayer separation and metallic nature of the 1H layer, positive bias voltages result in a pronounced superposition of the 1T charge density wave structure on the 1H layer. The conventional explanation relying on tunneling effects proves insufficient. Through a comprehensive investigation combining low-temperature scanning tunneling microscopy, scanning tunneling spectroscopy, non-contact atomic force microscopy, and first-principles calculations, we propose an alternative interpretation. The transparency effect arises from a weak yet substantial electronic coupling between the 1H and 1T layers, challenging prior understanding of the system. Our results highlight the critical role played by interlayer electronic interactions in van der Waals heterostructures to determine the final ground states of the systems.

8.
BMC Musculoskelet Disord ; 25(1): 448, 2024 Jun 06.
Artículo en Inglés | MEDLINE | ID: mdl-38844912

RESUMEN

INTRODUCTION: Fractures of the scaphoid are the most common carpal injuries, account for 80-90% of all carpal fractures. 5-15% nonunion of scaphoid fractures were reported even with adequate primary treatment, which probably progresses to osteoarthritic changes several decades later. Researches regarding to scaphoid physiological characteristic in vitro and in vivo and kinds of trials in clinical practice are being kept on going, which contribute much to our clinical practice. With the advancing wrist arthroscopy, 3D-print patient-specific drill guide, and intraoperative fluoroscopic guidance, dorsal approach (mini-invasive and percutaneous technique) is being popular, through which we can implant the screw in good coincidence with biomechanics and with less disturbing tenuous blood supply of the scaphoid. Investigating the noncontact area of the dorsal proximal scaphoid in different wrist positions can facilitate preoperatively estimating insert point of the screw. MATERIALS AND METHODS: Eight volunteers were recruited to accept CT scans in six extreme wrist positions. The images of DICOM mode were imput into the Mimics analytical system, the segmented scaphoid, lunate and radius were exported in mode of ASCII STL and were opened in the software of Geomagic studio. We created four planes based on anatomic markers on the surface of the radius and scaphoid to confine the proximal scaphoid to form the so-called non-contact regions. We measured and compared the areas in six targeted positions. RESULTS: Amidst six extreme wrist positions, area of the non-contact region in extreme dorsal extension (59.81 ± 26.46 mm2) was significantly the smallest, and it in extreme palmar flexion significantly was largest (170.51 ± 30.44 mm2). The non-contact regions increased in order of dorsal extension, supination, ulnar deviation, radial deviation, pronation and palmar flexion. As for two-group comparison, the non-contact region showed significantly larger (p < 0.05) in palmar flexion than the others except for in pronation individually, and in radial deviation (p < 0.05) than in dorsal extension. CONCLUSIONS: Sufficient space was available for the screw started from the dorsal approach despite the wrist positions.


Asunto(s)
Hueso Escafoides , Articulación de la Muñeca , Humanos , Hueso Escafoides/cirugía , Hueso Escafoides/lesiones , Hueso Escafoides/diagnóstico por imagen , Masculino , Adulto , Articulación de la Muñeca/cirugía , Articulación de la Muñeca/diagnóstico por imagen , Femenino , Tomografía Computarizada por Rayos X , Tornillos Óseos , Adulto Joven , Rango del Movimiento Articular , Pronación/fisiología , Fenómenos Biomecánicos
9.
Exploration (Beijing) ; 4(1): 20230073, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38854489

RESUMEN

Thromboelastography (TEG) remains a convenient and effective viscoelastic blood coagulation testing device for guiding blood component transfusion and assessing the risk of thrombosis. Here, a TEG enabled by a non-contact triboelectric angle sensor (NTAS) with a small size (∼7 cm3) is developed for assessing the blood coagulation system. With the assistance of a superelastic torsion wire structure, the NTAS-TEG realizes the detection of blood viscoelasticity. Benefiting from a grating and convex design, the NTAS holds a collection of compelling features, including accurate detection of rotation angles from -2.5° to 2.5°, high linearity (R 2 = 0.999), and a resolution of 0.01°. Besides, the NTAS exhibits merits of low cost and simplified fabrication. Based on the NTAS-TEG, a viscoelastic blood coagulation detection and analysis system is successfully constructed, which can provide a graph and parameters associated with clot initiation, formation, and stability for clinicians by using 0.36 mL of whole blood. The system not only validates the feasibility of the triboelectric coagulation testing sensor, but also further expands the application of triboelectric sensors in healthcare.

10.
Child Abuse Negl ; 154: 106908, 2024 Jun 25.
Artículo en Inglés | MEDLINE | ID: mdl-38925011

RESUMEN

BACKGROUND: Recent research argues for a formalized hybrid risk assessment model that combines the current online child sex abuse risk measures with digital forensics artifacts. OBJECTIVE: We conducted a feasibility study as an initial step toward formalizing the hybrid risk assessment model by identifying high-level digital forensic artifacts that have the potential to be valid and reliable indicators of risk, with a focus on CPORT Items 5, 6, and 7. DATA: Law enforcement investigators from a High Tech Crime Unit (HTCU) randomly selected seven closed cases; selection criteria included: male offender over 18, mobile device, child sexual abuse material (CSAM) offense, and 2019-2023 index offense. Investigation details related to probable cause, final charges, conviction, and offender risk were not disclosed. Statistical information (f, %) for the following digital forensics artifacts was examined: 1) pornography collection (e.g., % of media, content type, gender ratio) and 2) evidence of networking/grooming and other problematic online activities (e.g., number of native messages vs. application messages; type of installed apps). METHOD: The analysis predicted whether the offender was a CSAM-only or dual offender and if our findings agreed with the level of risk for reoffending suggested by CPORT Items 5, 6, and 7. Results were shared with the HTCU and scored for accuracy. RESULTS: The hybrid model was accurate in 6 of 7 cases. CONCLUSION: We conclude a hybrid model is feasible, and the findings illustrate the importance of analyzing app artifacts for context. Study limitations and future research recommendations are discussed.

11.
Sensors (Basel) ; 24(12)2024 Jun 19.
Artículo en Inglés | MEDLINE | ID: mdl-38931747

RESUMEN

The development of non-contact techniques for monitoring human vital signs has significant potential to improve patient care in diverse settings. By facilitating easier and more convenient monitoring, these techniques can prevent serious health issues and improve patient outcomes, especially for those unable or unwilling to travel to traditional healthcare environments. This systematic review examines recent advancements in non-contact vital sign monitoring techniques, evaluating publicly available datasets and signal preprocessing methods. Additionally, we identified potential future research directions in this rapidly evolving field.


Asunto(s)
Signos Vitales , Humanos , Signos Vitales/fisiología , Monitoreo Fisiológico/métodos , Procesamiento de Señales Asistido por Computador
12.
Sheng Wu Yi Xue Gong Cheng Xue Za Zhi ; 41(3): 461-468, 2024 Jun 25.
Artículo en Chino | MEDLINE | ID: mdl-38932531

RESUMEN

To achieve non-contact measurement of human heart rate and improve its accuracy, this paper proposes a method for measuring human heart rate based on multi-channel radar data fusion. The radar data were firstly extracted by human body position identification, phase extraction and unwinding, phase difference, band-pass filtering optimized by power spectrum entropy, and fast independent component analysis for each channel data. After overlaying and fusing the four-channel data, the heartbeat signal was separated using frost-optimized variational modal decomposition. Finally, a chirp Z-transform was introduced for heart rate estimation. After validation with 40 sets of data, the average root mean square error of the proposed method was 2.35 beats per minute, with an average error rate of 2.39%, a Pearson correlation coefficient of 0.97, a confidence interval of [-4.78, 4.78] beats per minute, and a consistency error of -0.04. The experimental results show that the proposed measurement method performs well in terms of accuracy, correlation, and consistency, enabling precise measurement of human heart rate.


Asunto(s)
Algoritmos , Frecuencia Cardíaca , Radar , Procesamiento de Señales Asistido por Computador , Humanos , Frecuencia Cardíaca/fisiología
13.
Front Med (Lausanne) ; 11: 1421901, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38933102

RESUMEN

The continuous monitoring of the health status of patients is essential for the effective monitoring of disease progression and the management of symptoms. Recently, health monitoring using non-contact sensors has gained interest. Therefore, this study aimed to investigate the use of non-contact sensors for health monitoring in hospital settings and evaluate their potential clinical applications. A comprehensive literature search was conducted using PubMed to identify relevant studies published up to February 26, 2024. The search terms included "hospital," "monitoring," "sensor," and "non-contact." Studies that used non-contact sensors to monitor health status in hospital settings were included in this review. Of the 38 search results, five studies met the inclusion criteria. The non-contact sensors described in the studies were radar, infrared, and microwave sensors. These non-contact sensors were used to obtain vital signs, such as respiratory rate, heart rate, and body temperature, and were then compared with the results from conventional measurement methods (polysomnography, nursing records, and electrocardiography). In all the included studies, non-contact sensors demonstrated a performance similar to that of conventional health-related parameter measurement methods. Non-contact sensors are expected to be a promising solution for health monitoring in hospital settings.

14.
Physiol Behav ; 283: 114619, 2024 Sep 01.
Artículo en Inglés | MEDLINE | ID: mdl-38917929

RESUMEN

Driver drowsiness is a significant factor in road accidents. Thermal imaging has emerged as an effective tool for detecting drowsiness by enabling the analysis of facial thermal patterns. However, it is not clear which facial areas are most affected and correlate most strongly with drowsiness. This study examines the variations and importance of various facial areas and proposes an approach for detecting driver drowsiness. Twenty participants underwent tests in a driving simulator, and temperature changes in various facial regions were measured. The random forest method was employed to evaluate the importance of each facial region. The results revealed that temperature changes in the nasal area exhibited the highest value, while the eyes had the most correlated changes with drowsiness. Furthermore, drowsiness was classified with an accuracy of 88 % utilizing thermal variations in the facial region identified as the most important regions by the random forest feature importance model. These findings provide a comprehensive overview of facial thermal imaging for detecting driver drowsiness and introduce eye temperature as a novel and effective measure for investigating cognitive activities.


Asunto(s)
Conducción de Automóvil , Cara , Aprendizaje Automático , Humanos , Masculino , Femenino , Adulto , Adulto Joven , Fases del Sueño/fisiología , Termografía/métodos , Somnolencia , Temperatura Corporal/fisiología , Simulación por Computador
15.
Sensors (Basel) ; 24(11)2024 May 22.
Artículo en Inglés | MEDLINE | ID: mdl-38894090

RESUMEN

This paper presents an overview of integrating new research outcomes into the development of a structural health monitoring strategy for the floating cover at the Western Treatment Plant (WTP) in Melbourne, Australia. The size of this floating cover, which covers an area of approximately 470 m × 200 m, combined with the hazardous environment and its exposure to extreme weather conditions, only allows for monitoring techniques based on remote sensing. The floating cover is deformed by the accumulation of sewage matter beneath it. Our research has shown that the only reliable data for constructing a predictive model to support the structural health monitoring of this critical asset is obtained directly from the actual floating cover at the sewage treatment plant. Our recent research outcomes lead us towards conceptualising an advanced engineering analysis tool designed to support the future creation of a digital twin for the floating cover at the WTP. Foundational work demonstrates the effectiveness of an unmanned aerial vehicle (UAV)-based photogrammetry methodology in generating a digital elevation model of the large floating cover. A substantial set of data has been acquired through regular UAV flights, presenting opportunities to leverage this information for a deeper understanding of the interactions between operational conditions and the structural response of the floating cover. This paper discusses the current findings and their implications, clarifying how these outcomes contribute to the ongoing development of an advanced digital twin for the floating cover.

16.
Sensors (Basel) ; 24(11)2024 May 30.
Artículo en Inglés | MEDLINE | ID: mdl-38894333

RESUMEN

In recent years, hypertension has become one of the leading causes of illness and death worldwide. Changes in lifestyle among the population have led to an increasing prevalence of hypertension. This study proposes a non-contact blood pressure estimation method that allows patients to conveniently monitor their blood pressure values. By utilizing a webcam to track facial features and the region of interest (ROI) for obtaining forehead images, independent component analysis (ICA) is employed to eliminate artifact signals. Subsequently, physiological parameters are calculated using the principle of optical wave reflection. The Nelder-Mead (NM) simplex method is combined with the particle swarm optimization (PSO) algorithm to optimize the empirical parameters, thus enhancing computational efficiency and accurately determining the optimal solution for blood pressure estimation. The influences of light intensity and camera distance on the experimental results are also discussed. Furthermore, the measurement time is only 10 s. The superior accuracy and efficiency of the proposed methodology are demonstrated by comparing them with those in other published literature.


Asunto(s)
Algoritmos , Determinación de la Presión Sanguínea , Presión Sanguínea , Humanos , Presión Sanguínea/fisiología , Determinación de la Presión Sanguínea/métodos , Hipertensión/fisiopatología , Hipertensión/diagnóstico , Procesamiento de Señales Asistido por Computador
17.
PeerJ ; 12: e17570, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38903879

RESUMEN

Objectives: This study sought to evaluate the diagnostic value of a non-contact optical fiber mattress for apnea and hypopnea and compare it with traditional polysomnography (PSG) in adult obstructive sleep apnea hypopnea syndrome (OSAHS). Methods: To determine the value of a non-contact optical fiber mattress for apnea and hypopnea, six healthy people and six OSAHS patients were selected from Tongji Hospital to design a program to identify apnea or hypopnea. A total of 108 patients who received polysomnography for drowsiness, snoring or other suspected OSAHS symptoms. All 108 patients were monitored with both the non-contact optical fiber mattress and PSG were collected. Results: Six healthy controls and six patients with OSAHS were included. The mean apnea of the six healthy controls was 1.22 times/h, and the mean hypopnea of the six healthy controls was 2 times/h. Of the six patients with OSAHS, the mean apnea was 12.63 times/h, and the mean hypopnea was 19.25 times/h. The non-contact optical fiber mattress results showed that the mean apnea of the control group was 3.17 times/h and the mean hypopnea of the control group was 3.83 times/h, while the mean apnea of the OSAHS group was 11.95 times/h and the mean hypopnea of the OSAHS group was 17.77 times/h. The apnea index of the non-contact optical fiber mattress was positively correlated with the apnea index of the PSG (P < 0.05, r = 0.835), and the hypopnea index of the non-contact optical fiber mattress was also positively correlated with the hypopnea index of the PSG (P < 0.05, r = 0.959). The non-contact optical fiber mattress had high accuracy (area under curve, AUC = 0.889), specificity (83.4%) and sensitivity (83.3%) for the diagnosis of apnea. The non-contact fiber-optic mattress also had high accuracy (AUC = 0.944), specificity (83.4%) and sensitivity (100%) for the diagnosis of hypopnea. Among the 108 patients enrolled, there was no significant difference between the non-contact optical fiber mattress and the polysomnography monitor in total recording time, apnea hypopnea index (AHI), average heart rate, tachycardia index, bradycardia index, longest time of apnea, average time of apnea, longest time of hypopnea, average time of hypopnea, percentage of total apnea time in total sleep time and percentage of total hypopnea time in total sleep time. The AHI value of the non-contact optical fiber mattress was positively correlated with the AHI value of the PSG (P < 0.05, r = 0.713). The specificity and sensitivity of the non-contact optical fiber mattress AHI in the diagnosis of OSAHS were 95% and 93%, with a high OSAHS diagnostic accuracy (AUC = 0.984). Conclusion: The efficacy of the non-contact optical fiber mattress for OSAHS monitoring was not significantly different than PSG monitoring. The specificity of the non-contact optical mattress for diagnosing OSAHS was 95% and its sensitivity was 93%, with a high OSAHS diagnostic accuracy.


Asunto(s)
Fibras Ópticas , Polisomnografía , Apnea Obstructiva del Sueño , Humanos , Apnea Obstructiva del Sueño/diagnóstico , Masculino , Polisomnografía/instrumentación , Polisomnografía/métodos , Femenino , Persona de Mediana Edad , Estudios Retrospectivos , Adulto , Lechos , Sensibilidad y Especificidad , Estudios de Casos y Controles , Anciano
18.
Beilstein J Nanotechnol ; 15: 580-602, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38887532

RESUMEN

Non-contact atomic force microscopy (nc-AFM) offers a unique experimental framework for topographical imaging of surfaces with atomic and/or sub-molecular resolution. The technique also permits to perform frequency shift spectroscopy to quantitatively evaluate the tip-sample interaction forces and potentials above individual atoms or molecules. The stiffness of the probe, k, is then required to perform the frequency shift-to-force conversion. However, this quantity is generally known with little precision. An accurate stiffness calibration is therefore mandatory if accurate force measurements are targeted. In nc-AFM, the probe may either be a silicon cantilever, a quartz tuning fork (QTF), or a length extensional resonator (LER). When used in ultrahigh vacuum (UHV) and at low temperature, the technique mostly employs QTFs, based on the so-called qPlus design, which actually covers different types of sensors in terms of size and design of the electrodes. They all have in common a QTF featuring a metallic tip glued at the free end of one of its prongs. In this study, we report the stiffness calibration of a particular type of qPlus sensor in UHV and at 9.8 K by means of thermal noise measurements. The stiffness calibration of such high-k sensors, featuring high quality factors (Q) as well, requires to master both the acquisition parameters and the data post-processing. Our approach relies both on numerical simulations and experimental results. A thorough analysis of the thermal noise power spectral density of the qPlus fluctuations leads to an estimated stiffness of the first flexural eigenmode of ≃2000 N/m, with a maximum uncertainty of 10%, whereas the static stiffness of the sensor without tip is expected to be ≃3300 N/m. The former value must not be considered as being representative of a generic value for any qPlus, as our study stresses the influence of the tip on the estimated stiffness and points towards the need for the individual calibration of these probes. Although the framework focuses on a particular kind of sensor, it may be adapted to any high-k, high-Q nc-AFM probe used under similar conditions, such as silicon cantilevers and LERs.

19.
J Pediatr Nurs ; 77: e616-e624, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38824078

RESUMEN

BACKGROUND: This study was conducted to compare the accuracy of two noninvasive thermometers (axillary and infrared non-contact forehead thermometer) in measuring core temperature compared to the gold standard oral thermometer in the detection of fever in pediatric cancer patients with febrile neutropenia. METHODS: The study was conducted with a single group of 42 children with febrile neutropenia between 23 December 2020 and 25 January 2023 in the pediatric hematology and oncology clinic of a training and research hospital, which provides a specialized environment for both medical education and advanced scientific research in the field of pediatric hematology and oncology. The participants' body temperature was measured with an oral, axillary, and non-contact infrared forehead thermometer immediately after admission to the clinic and at 5 and 10 min after admission. The inter-rater agreement for each method and inter-method agreement between axillary and non-contact infrared temperature readings and oral readings were analyzed for each time point using intraclass correlation coefficients (ICC). RESULTS: The children in the study had a mean age of 11.62 ± 3.00 years and 28 (66.7%) were boys, 19 (45.2%) were younger children (5-10 years of age), and 23 (54.8%) were adolescents (11-16 years of age). In the analysis of agreement between the thermometers at admission and at 5 and 10 min after admission in children with febrile neutropenia, the highest agreement was between the oral and axillary thermometers (ICC: 0.584, 0.835, 0.536, respectively) and the lowest agreement was between the oral and non-contact infrared thermometers (ICC: 0.219, 0.022, 0.473, respectively). CONCLUSION: Compared to orally measured body temperature, axillary temperature readings showed better agreement than non-contact infrared temperature readings from the forehead in pediatric patients with febrile neutropenia. PRACTICE IMPLICATIONS: The research findings may guide nurses and families caring for pediatric patients with febrile neutropenia and should contribute to the prevention of false findings of fever and the reduction of its adverse consequences.


Asunto(s)
Temperatura Corporal , Neutropenia Febril , Neoplasias , Termómetros , Humanos , Niño , Masculino , Femenino , Adolescente , Neutropenia Febril/diagnóstico , Neoplasias/complicaciones , Temperatura Corporal/fisiología , Preescolar , Axila , Fiebre/diagnóstico
20.
Healthcare (Basel) ; 12(12)2024 Jun 13.
Artículo en Inglés | MEDLINE | ID: mdl-38921307

RESUMEN

Vital signs are crucial for assessing the condition of a patient and detecting early symptom deterioration. Noncontact sensor technology has been developed to take vital measurements with minimal burden. This study evaluated the accuracy of a mat-type noncontact sensor in measuring respiratory and pulse rates in patients with cardiovascular diseases compared to conventional methods. Forty-eight hospitalized patients were included; a mat-type sensor was used to measure their respiratory and pulse rates during bed rest. Differences between mat-type sensors and conventional methods were assessed using the Bland-Altman analysis. The mean difference in respiratory rate was 1.9 breaths/min (limits of agreement (LOA): -4.5 to 8.3 breaths/min), and proportional bias existed with significance (r = 0.63, p < 0.05). For pulse rate, the mean difference was -2.0 beats/min (LOA: -23.0 to 19.0 beats/min) when compared to blood pressure devices and 0.01 beats/min (LOA: -11.4 to 11.4 beats/min) when compared to 24-h Holter electrocardiography. The proportional bias was significant for both comparisons (r = 0.49, p < 0.05; r = 0.52, p < 0.05). These were considered clinically acceptable because there was no tendency to misjudge abnormal values as normal. The mat-type noncontact sensor demonstrated sufficient accuracy to serve as an alternative to conventional assessments, providing long-term monitoring of vital signs in clinical settings.

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