RESUMEN
This perspective article delves into a novel integration of Yin-Yang theory-an ancient Chinese philosophical cornerstone-with the sophisticated realm of immunology. Given the intricate concepts inherent in immunology, many students find it challenging to comprehend the delicate mechanisms governing immune equilibrium and regulation. Given the deep-rooted understanding of Yin-Yang theory among Chinese students, we advocate for an educational strategy that contextualizes the concept of immune equilibrium within the framework of Yin-Yang, thereby offering a more intuitive and engaging learning experience. This method not only capitalizes on the cultural significance of Yin-Yang, but also corresponds to its principles of equilibrium and harmony, thus mirroring the homeostatic essence of immune responses. This article critically assesses this technique's capacity to bolster immune comprehension amongst Chinese students, while also considering its limitations. Despite these limitations, the fusion of these seemingly divergent fields holds substantial promise for augmenting immunology education, promoting critical thinking, and advancing cross-cultural academic discourse. The amalgamation of age-old philosophical insights with modern scientific exploration prompts a reassessment of educational methodologies within immunology, underscoring a novel pedagogical approach that bridges traditional wisdom with contemporary scientific education.
Asunto(s)
Alergia e Inmunología , Yin-Yang , Alergia e Inmunología/educación , Alergia e Inmunología/historia , Humanos , Enseñanza , ChinaRESUMEN
What are the future directions of the fields of developmental and comparative immunology? In thinking through this question as I write, I find myself marvelling at the very long ways that we have come since I began as a PhD student some 50 years ago. I think that we cannot know what technical and theoretical advances will emerge in the future, nor will our initial aims survive the realities of what appears in our sights, often from unexpected directions. I feel that we should not allow what we already know about some well-studied systems to blind us to the wide range of possibilities, and that remaining a humble seeker helps the uptake of new realities. Finally, it would be good to try answering the whole range of questions about developmental and comparative immunology, from what to how to why.
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Alergia e Inmunología , Animales , Alergia e Inmunología/historia , Humanos , Biología Evolutiva , Historia del Siglo XX , Historia del Siglo XXI , Fisiología ComparadaRESUMEN
In this article, I aim to give some pieces of career advise for young immunologists based on my own experiences.
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Alergia e Inmunología , Selección de Profesión , Humanos , Alergia e Inmunología/historiaRESUMEN
Over the past 30 years, the field of cardioimmunology has moved from being dismissed as a field that was chasing an epiphenomenon of little biological consequence to a scientific discipline that is providing important new insights into the immunologic basis for hypertension, atherosclerosis, myocarditis, pericarditis, autoimmune heart disease, and heart failure. In this article, we will review the conceptual insights and technical breakthroughs that have allowed the field to move forward, as well as the clinical trials in the cardioimmunology space, to provide a historical context for the articles that will appear in the compendium that is focused on the interface between cardioimmunology, myocardial function, and disease.
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Cardiopatías , Humanos , Animales , Cardiopatías/inmunología , Cardiopatías/terapia , Alergia e Inmunología/tendencias , Alergia e Inmunología/historia , Enfermedades Cardiovasculares/inmunología , Historia del Siglo XXI , Historia del Siglo XXRESUMEN
Art is a powerful tool for conveying scientific discovery. Despite the perceived gap between art and science, as highlighted by CP Snow and others, examples of art communicating science can be found in the ancient world, the Renaissance and contemporary data visualization, demonstrating an enduring and historic connection. However, much of science relies on visual elements, excluding those with blindness, low vision and diverse needs, resulting in their low representation in STEM discourse. This paper introduces a novel science and art collaboration in the form of an exhibition program exploring the concepts of Immunology and Biomedicine to blind and vision-impaired audiences, capitalizing on the lived experience of a legally blind artist. Employing multisensory design, art and co-creation methodologies, it transcends traditional vision-based science communication, showcasing the potential for multisensory art to bridge the gap at the intersection of science and inclusion.
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Alergia e Inmunología , Arte , Humanos , Alergia e Inmunología/historia , Ceguera/inmunología , Ceguera/terapia , Baja Visión/inmunología , CienciaAsunto(s)
Receptores de Antígenos de Linfocitos T , Humanos , Receptores de Antígenos de Linfocitos T/metabolismo , Receptores de Antígenos de Linfocitos T/inmunología , Investigación Biomédica Traslacional/historia , Animales , Historia del Siglo XX , Historia del Siglo XXI , Alergia e Inmunología/historia , Linfocitos T/inmunologíaRESUMEN
This "Focus on Immunology" issue brings Cell's 50th anniversary celebrations straight to your lymph nodes! Special Leading Edge articles highlight the exciting past, present, and future of the increasingly interdisciplinary field of immunology.
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Alergia e Inmunología , Humanos , Alergia e Inmunología/historia , Animales , Ganglios Linfáticos/inmunologíaAsunto(s)
Tutoría , Mentores , Humanos , Historia del Siglo XXI , Alergia e Inmunología/historia , Historia del Siglo XXRESUMEN
Over the past 50 years in the field of immunology, something of a Copernican revolution has happened. For a long time, immunologists were mainly concerned with what is termed adaptive immunity, which involves the exquisitely specific activities of lymphocytes. But the other arm of immunity, so-called "innate immunity," had been neglected. To celebrate Cell's 50th anniversary, we have put together a review of the processes and components of innate immunity and trace the seminal contributions leading to the modern state of this field. Innate immunity has joined adaptive immunity in the center of interest for all those who study the body's defenses, as well as homeostasis and pathology. We are now entering the era where therapeutic targeting of innate immune receptors and downstream signals hold substantial promise for infectious and inflammatory diseases and cancer.
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Inmunidad Innata , Humanos , Animales , Historia del Siglo XX , Historia del Siglo XXI , Inmunidad Adaptativa , Alergia e Inmunología/historiaRESUMEN
In this short review, examples of unnecessary multiple names of cell membrane molecules, for example, immune checkpoints and cytokines, are presented. Moreover, ridiculous or inaccurate names, such as 'Regulated on activation, normal T-cell expressed and secreted' and 'tissue factor', are discussed.
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Alergia e Inmunología , Terminología como Asunto , Humanos , Alergia e Inmunología/historia , Citocinas/inmunología , Animales , Proteínas de Punto de Control Inmunitario/genética , Proteínas de Punto de Control Inmunitario/metabolismoRESUMEN
This Commentary article reviews the history of veterinary immunology in Australia from the 1980s and discusses the key people and areas of research during this period.
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Alergia e Inmunología , Medicina Veterinaria , Australia , Medicina Veterinaria/historia , Alergia e Inmunología/historia , Historia del Siglo XXRESUMEN
This article honors the memory of Nilabh Shastri by recounting the messages sent to him by his friend and colleagues. In addition to his obvious gifts as a scientist, he was a treasured mentor, colleague and friend who enriched the lives of those he touched.
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Alergia e Inmunología/historia , Tutoría , Estudiantes , Historia del Siglo XX , Historia del Siglo XXI , HumanosRESUMEN
In this article, we describe the development of the plant immunity field, starting with efforts to understand the genetic basis for disease resistance, which â¼30 y ago led to the discovery of diverse classes of immune receptors that recognize and respond to infectious microbes. We focus on knowledge gained from studies of the rice XA21 immune receptor that recognizes RaxX (required for activation of XA21 mediated immunity X), a sulfated microbial peptide secreted by the gram-negative bacterium Xanthomonas oryzae pv. oryzae. XA21 is representative of a large class of plant and animal immune receptors that recognize and respond to conserved microbial molecules. We highlight the complexity of this large class of receptors in plants, discuss a possible role for RaxX in Xanthomonas biology, and draw attention to the important role of sulfotyrosine in mediating receptor-ligand interactions.