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1.
Front Public Health ; 12: 1371598, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38689772

RESUMEN

Background: Humanitarian emergencies are a major global health challenge with the potential to have a profound impact on people's mental and psychological health. Displacement is a traumatic event that disrupts families and affects physical and psychological health at all ages. A person may endure or witness a traumatic incident, such as being exposed to war, and, as a result, develop post-traumatic stress disorder (PTSD). There is a lack of information about post-traumatic stress disorder, depression, and anxiety disorder in low and middle-income countries in humanitarian emergency contexts such as Mozambique. This study aimed to assess the prevalence of PTSD, depression, and anxiety, and associated factors among armed conflict survivors in Cabo Delgado, north region of Mozambique in 2023. Methods: A community-based cross-sectional study was conducted between January and April 2023 among 750 participants, who were selected by convenience. A face-to-face interview used the Primary Care Post-Traumatic Stress Disorder Checklist (PC-PTSD-5) to evaluate PTSD, the Generalized Anxiety Disorder Scale (GAD-7) to evaluate anxiety and the Patient Health Questionnaire - Mozambique (PHQ-9 MZ) to evaluate depression. The association between PTSD and demographic and psychosocial characteristics was analyzed using bivariate and multivariable binary logistic regression. We used a 5% significance level. Results: The three mental disorders assessed were highly prevalent in our sample with 74.3% PTSD, 63.8% depression, and 40.0% anxiety. The chance of developing PTSD was higher in females (AOR = 2.30, 95% CI 1.50-3.51), in patients with depression symptoms (AOR = 8.27, 95% CI = 4.97-13.74) and anxiety symptoms (AOR = 1.45, 95% CI = 0.84-2.50). Conclusion: This study reported that the prevalence of PTSD, depression, and anxiety were high. Patients having depressive symptoms, anxiety symptoms, and being female are more at risk of developing PTSD. There is a need to integrate screening for common mental disorders in the context of humanitarian emergencies and its adapted integration of psychosocial interventions.


Asunto(s)
Conflictos Armados , Refugiados , Trastornos por Estrés Postraumático , Humanos , Estudios Transversales , Mozambique/epidemiología , Femenino , Masculino , Adulto , Prevalencia , Trastornos por Estrés Postraumático/epidemiología , Conflictos Armados/psicología , Refugiados/psicología , Refugiados/estadística & datos numéricos , Persona de Mediana Edad , Depresión/epidemiología , Ansiedad/epidemiología , Adolescente , Adulto Joven , Factores de Riesgo , Trastornos Mentales/epidemiología , Encuestas y Cuestionarios
2.
Glob Public Health ; 19(1): 2346947, 2024 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-38718290

RESUMEN

Young people in Colombia present high rates of mental health problems, to which the country's history of armed internal conflict contributes in complex ways. Mental health services in Colombia are fragmented, inadequate, and difficult to access for many. Young people's help-seeking is often hindered by mental health stigma and/or poor experiences with services. This paper presents a thematic analysis of qualitative data from a mixed-methods study aimed at developing and testing a mental health intervention for Colombian youths. We draw upon theoretical lenses from scholarly work on stigma and Sen's 'capabilities approach' to inform our analysis of interviews and group discussions with staff and young people involved in the state-funded human capital building programme 'Jovenes en Acción' (JeA). By illustrating how study participants talked about stigma, vulnerability, mental health services organisation, and the challenges of discussing mental health topics in a learning environment, we illuminate aspects of mental health support and anti-stigma interventions that might need enhancing. In particular, we suggest that more emphasis on 'community competencies' as complementary to and interrelated with individual competencies would strengthen young people's individual and collective resources for mental wellbeing while being in line with the sociocritical principles of existing human capital-enhancing programmes.


Asunto(s)
Entrevistas como Asunto , Servicios de Salud Mental , Investigación Cualitativa , Estigma Social , Humanos , Colombia , Adolescente , Femenino , Masculino , Adulto Joven , Conflictos Armados , Salud Mental , Trastornos Mentales
3.
J Med Virol ; 96(5): e29651, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38712743

RESUMEN

Understanding how the infectious disease burden was affected throughout the COVID-19 pandemic is pivotal to identifying potential hot spots and guiding future mitigation measures. Therefore, our study aimed to analyze the changes in the rate of new cases of Poland's most frequent infectious diseases during the entire COVID-19 pandemic and after the influx of war refugees from Ukraine. We performed a registry-based population-wide study in Poland to analyze the changes in the rate of 24 infectious disease cases from 2020 to 2023 and compared them to the prepandemic period (2016-2019). Data were collected from publicly archived datasets of the Epimeld database published by national epidemiological authority institutions. The rate of most of the studied diseases (66.6%) revealed significantly negative correlations with the rate of SARS-CoV-2 infections. For the majority of infectious diseases, it substantially decreased in 2020 (in case of 83%) and 2021 (63%), following which it mostly rebounded to the prepandemic levels and, in some cases, exceeded them in 2023 when the exceptionally high annual rates of new cases of scarlet fever, Streptococcus pneumoniae infections, HIV infections, syphilis, gonococcal infections, and tick-borne encephalitis were noted. The rate of Clostridioides difficile enterocolitis was two-fold higher than before the pandemic from 2021 onward. The rate of Legionnaires' disease in 2023 also exceeded the prepandemic threshold, although this was due to a local outbreak unrelated to lifted COVID-19 pandemic restrictions or migration of war refugees. The influx of war migrants from Ukraine could impact the epidemiology of sexually transmitted diseases. The present analysis indicates that continued efforts are needed to prevent COVID-19 from overwhelming healthcare systems again and decreasing the control over the burden of other infectious diseases. It also identifies the potential tipping points that require additional mitigation measures, which are also discussed in the paper, to avoid escalation in the future.


Asunto(s)
COVID-19 , Enfermedades Transmisibles , Refugiados , Humanos , COVID-19/epidemiología , Ucrania/epidemiología , Polonia/epidemiología , Refugiados/estadística & datos numéricos , Enfermedades Transmisibles/epidemiología , SARS-CoV-2 , Femenino , Masculino , Pandemias , Adulto , Sistema de Registros , Costo de Enfermedad , Conflictos Armados
4.
PLoS One ; 19(5): e0302405, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38709775

RESUMEN

This study investigates the effects of the Russia-Ukraine conflict on the quality and quantity of Malaysia's palm oil production through a time series analysis. The study uses three primary factors to evaluate palm oil production: the Monthly Oil Extraction Rate (OER), the Monthly Fresh Fruit Bunch (FFB) Yield, and the Monthly Oil Exports. The results indicate that the Russia-Ukraine conflict significantly impacted the quality and quantity of palm oil production in Malaysia. Marginal declines in both the quality and quantity of palm oil produced at the onset of the conflict indicate a slight but significant decline in palm oil production during the next four-year period.


Asunto(s)
Aceite de Palma , Malasia , Federación de Rusia , Conflictos Armados , Aceites de Plantas
5.
6.
Front Public Health ; 12: 1271028, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38645448

RESUMEN

Background: The war that started on November 4, 2020, in the Tigray region of Northern Ethiopia severely affected the health sector. However, there is no available evidence to suggest the economic damage caused to the public health system because of war-related looting or vandalism. This study was aimed at estimating the cost of war-related looting or vandalism in Tigray's public health system in Northern Ethiopia in 2021. Methods: A provider perspective, a mixed costing method, a retrospective cross-sectional approach, a 50% inflation rate, and a 50 Ethiopian birr equivalent to one United States dollar ($) for the money value were used. The data were analyzed using Microsoft Excel, taking into consideration the Sendai framework indicators. Results: The total economic cost of the war-related looting or vandalism in monetary terms was more than $3.78 billion, and the damage to the economic value in monetary terms was more than $2.31 billion. Meanwhile, the direct economic loss to the health system in monetary terms was more than $511 million. According to this assessment, 514 (80.6%) health posts, 153 (73.6%) health centers, 16 (80%) primary hospitals, 10 (83.3%) general hospitals, and 2 (100%) specialized hospitals were damaged and/or vandalized either fully or partially due to the war. Conclusion: This war seriously affected the public health sector in the Tigray region. The Federal Government of Ethiopia, the Ministry of Health of Ethiopia, the Tigrayan Government, the Tigray Regional Health Bureau, and the international community must make efforts to find resources for the revitalization of the damaged, plundered, and vandalized healthcare system.


Asunto(s)
Conflictos Armados , Servicios de Salud , Servicios de Salud/economía , Servicios de Salud/estadística & datos numéricos , Conflictos Armados/estadística & datos numéricos , Atención a la Salud/economía , Atención a la Salud/estadística & datos numéricos , Costos y Análisis de Costo
7.
Radiat Environ Biophys ; 63(2): 263-269, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38668870

RESUMEN

This work investigates the impact on cosmic ray exposures to aircrew due to changing flight routes operated in the context of the recent conflict between Ukraine and the Russian Federation. All analyses were done based on Paris-Tokyo and Tokyo-Paris flights taken as examples, and differences in radiation exposures were quantified by comparing the situation before and after the beginning of the conflict. Regarding space weather scenarios, a quiet solar period and an extreme solar event (ground level enhancement (GLE) 5) were considered in the study. Analyses showed that the new Paris-Tokyo flight route established after the beginning of the conflict results in a smaller radiation dose to aircrew than that operated before the conflict, particularly during solar events. In contrast, for Tokyo-Paris flights the new high-latitude route crossing the Atlantic Ocean and North America increases the dose significantly (+ 50% in the worst case). Although this analysis is limited only to flights connecting Paris and Tokyo, it allowed for an evaluation of the consequences of new routes (particularly polar ones) on ambient dose equivalent values.


Asunto(s)
Radiación Cósmica , Ucrania , Federación de Rusia , Humanos , Exposición Profesional/análisis , Aeronaves , Conflictos Armados , Dosis de Radiación , Monitoreo de Radiación
8.
Front Public Health ; 12: 1380626, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38633233

RESUMEN

In the midst of global armed conflicts, notably the Israel-Hamas and Ukraine-Russia wars, there is an urgent need for innovative public health strategies in peacebuilding. The devastating impact of wars, including mortality, injury, disease, and the diversion of healthcare resources, necessitates effective and durable interventions. This perspective aligns with WHO recommendations and examines the role of evidence-based meditation from Ayurveda and Yoga in public health to mitigate collective stress and prevent collective violence and war. It highlights the Transcendental Meditation program, recognized for reducing stress, with contemporary evidence supporting its effectiveness in mental health, mind-body disorders, cardiovascular disease, and public health. Empirical studies with cross-cultural replications indicate that these Traditional Medicine meditation practices can reduce collective stress and prevent collective violence and war activity while improving quality of life. The mechanisms of group meditation in mitigating collective violence are explored through public health models, cognitive neuroscience, population neuroscience, quantum physics principles, and systems medicine. This perspective suggests that Transcendental Meditation and the advanced TM-Sidhi program, as a component of Traditional Medicine, can provide a valuable platform for enhancing societal well-being and peace by addressing brain-based factors fundamental to collective stress and violence.


Asunto(s)
Meditación , Humanos , Calidad de Vida , Violencia/prevención & control , Violencia/psicología , Conflictos Armados , Medicina Tradicional
9.
Lancet ; 403(10437): 1630-1631, 2024 Apr 27.
Artículo en Inglés | MEDLINE | ID: mdl-38677851
10.
Soc Sci Med ; 348: 116777, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38569280

RESUMEN

BACKGROUND: Armed conflict and insecurity have been linked to deteriorations in reproductive health and rights globally. In Nigeria, armed violence has taken a significant toll on women's and girls' health and safety. However, knowledge is limited about how conflict shapes attitudes surrounding their ability to make autonomous decisions on relationships and childbearing. Drawing on a socioecological framework and terror management theory, we aimed to investigate the association between conflict, insecurity, and attitudes toward women's and girls' reproductive autonomy in Nigeria. METHODS: We conducted a cross-sectional study using data from two sources: the World Values Survey (WVS) and the Uppsala Conflict Data Program-Georeferenced Event Dataset (UCDP-GED). Nationally representative data on attitudes of 559 men and 534 women was collected by WVS in 2017-2018. Linear probability models estimated the association between attitudes toward five dimensions of women and girl's reproductive autonomy (contraception, safe abortion, marital decision-making, delayed childbearing, early marriage), respondents' perceptions of neighborhood insecurity using WVS data, and geospatial measures of conflict exposure drawn from UCDP-GED. RESULTS: Exposure to armed conflict and perceived neighborhood insecurity were associated with more supportive attitudes toward access to safe abortion among both men and women. Among women, conflict exposure was associated with higher support for contraception and the perception that early marriage can provide girls with security. Conflict-affected men were more likely to support a delay in girls' childbearing. CONCLUSION: Our findings suggest that conflict and insecurity pose a threat to, but also facilitate opportunities for, women's and girls' reproductive autonomy. Contraception, abortion, early marriage, and postponement or childbearing may be perceived as risk-aversion strategies in response to mortality threats, livelihood losses, and conflict-driven sexual violence. Our findings foreshadow changes in fertility and relationship patterns in conflict-affected Nigeria and highlight the need for health programming to ensure access to contraception and safe abortion services.


Asunto(s)
Conflictos Armados , Autonomía Personal , Humanos , Femenino , Nigeria , Estudios Transversales , Adulto , Conflictos Armados/psicología , Masculino , Adolescente , Persona de Mediana Edad , Encuestas y Cuestionarios , Adulto Joven , Actitud
11.
Soc Sci Med ; 348: 116710, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38636208

RESUMEN

Giving birth during adolescence is linked to a variety of negative outcomes, including poor health and well-being. Girls who have been displaced by conflict are at increased risk for becoming young mothers. While prevalence rates and health outcomes have been documented, rarely have the complex personal narratives of early motherhood been examined from the perspectives of mothers themselves, particularly in the Global South. This study relies on in-depth, inductive, narrative analysis of qualitative interviews with 67 young mothers and 10 relatives in South Sudan and the Kurdistan Region of Iraq (KRI) who had been displaced by conflict. This study provides deep insights into the contributing circumstances and consequences of young motherhood from sexual and reproductive health and well-being perspectives, with additional insights on mothering in humanitarian crisis.


Asunto(s)
Madres , Investigación Cualitativa , Refugiados , Humanos , Femenino , Sudán del Sur , Irak , Adolescente , Refugiados/psicología , Refugiados/estadística & datos numéricos , Madres/psicología , Madres/estadística & datos numéricos , Adulto Joven , Adulto , Embarazo , Embarazo en Adolescencia/psicología , Embarazo en Adolescencia/estadística & datos numéricos , Entrevistas como Asunto , Conflictos Armados/psicología
12.
JAMA Netw Open ; 7(4): e248510, 2024 Apr 01.
Artículo en Inglés | MEDLINE | ID: mdl-38669020

RESUMEN

Importance: Armed conflicts are directly and indirectly associated with morbidity and mortality due to destruction of health infrastructure and diversion of resources, forced displacement, environmental damage, and erosion of social and economic security. Colombia's conflict began in the 1940s and has been uniquely long-lasting and geographically dynamic. Objective: To estimate the proportion of infant and child mortality associated with armed conflict exposure from 1998 to 2019 in Colombia. Design, Setting, and Participants: This ecological cohort study includes data from all 1122 municipalities in Colombia from 1998 to 2019. Statistical analysis was conducted from February 2022 to June 2023. Exposure: Armed conflict exposure was measured dichotomously by the occurrence of conflict-related events in each municipality-year, enumerated and reported by the Colombian National Center for Historic Memory. Main Outcomes and Measures: Deaths among children younger than 5 years and deaths among infants younger than 1 year, offset by the number of births in that municipality-year, enumerated by Colombia's national vital statistics. Results: The analytical sample included 24 157 municipality-years and 223 101 conflict events covering the period from 1998 to 2019. Overall, the presence of armed conflict in a municipality was associated with a 52% increased risk of death for children younger than 5 years of age (relative risk, 1.52 [95% CI, 1.34-1.72]), with similar results for 1- and 5-year lagged analyses. Armed conflict was associated with a 61% increased risk in infant (aged <1 year) death (relative risk, 1.61 [95% CI, 1.43-1.82]). On the absolute scale, this translates to a risk difference of 3.7 excess child deaths per 1000 births (95% CI, 2.7-4.7 per 1000 births) and 3.0 excess infant deaths per 1000 births (95% CI, 2.3-3.6 per 1000 births) per year, beyond what would be expected in the absence of armed conflict. Across the 22-year study period, the population attributable risk was 31.7% (95% CI, 23.5%-39.1%) for child deaths and 35.3% (95% CI, 27.8%-42.0%) for infant deaths. Conclusions and Relevance: This ecological cohort study of Colombia's spatiotemporally dynamic armed conflict suggests that municipal exposure to armed conflict was associated with excess child and infant deaths. With a record number of children living near active conflict zones in 2020, policy makers and health professionals should understand the magnitude of and manner in which armed conflicts directly and indirectly undermine child health.


Asunto(s)
Conflictos Armados , Mortalidad del Niño , Mortalidad Infantil , Humanos , Colombia/epidemiología , Lactante , Mortalidad del Niño/tendencias , Preescolar , Femenino , Masculino , Mortalidad Infantil/tendencias , Recién Nacido , Estudios de Cohortes , Niño
13.
Artículo en Inglés | MEDLINE | ID: mdl-38673420

RESUMEN

The negative impact of the COVID-19 pandemic on mental health has been widely demonstrated; however, few studies have investigated the psychological processes involved in this impact, including core beliefs violation, meaning-making disruption, interpersonal support, or one's relational functioning. This study explored the mental health of 215 Italian adolescents during the COVID-19 pandemic and the subsequent outbreak of the Russian-Ukrainian war. By administering a set of questionnaires, several cognitive and emotional variables were investigated, including core belief violation, meaning attribution to the pandemic and war, attachment, and emotion regulation, social media addiction, and relationships with significant others and teachers. We conducted some descriptive, mean difference, correlational, and predictive analyses that revealed a significant association between core belief violation caused by war and pandemic, ability to integrate war and pandemic within personal meaning universe, the relational support received, and mental health. The relationship with teachers during these challenging periods improved significantly according to the respondents' opinion, becoming both more authoritative and empathic. This study offers insights into what cognitive and relational processes are useful to intervene on to reduce the distress of adolescents who are facing significant moments of crisis due to events that challenge their cognitive and emotional balance.


Asunto(s)
COVID-19 , Salud Mental , Estudiantes , Humanos , COVID-19/psicología , COVID-19/epidemiología , Adolescente , Italia/epidemiología , Masculino , Femenino , Estudiantes/psicología , Cognición , SARS-CoV-2 , Encuestas y Cuestionarios , Conflictos Armados/psicología , Federación de Rusia/epidemiología , Instituciones Académicas
14.
BMJ Open ; 14(4): e075957, 2024 Apr 05.
Artículo en Inglés | MEDLINE | ID: mdl-38582531

RESUMEN

OBJECTIVE: Armed conflicts and intimate partner violence (IPV) impose a burden on individual and societal well-being. Given the history of armed conflict in Afghanistan and the high prevalence of IPV, this study aims to examine the influence of armed conflicts on IPV among Afghan women. METHODS: Multilevel logistic regression models were applied to the 2015 Afghanistan Demographic and Health Survey (N=10 414 women aged 15-49). Armed conflict severity was measured using the conflict index issued by the Office for the Coordination of Humanitarian Affairs, IPV was measured by three types of violence, including emotional, physical and sexual violence. All analyses were conducted by using STATA V.15.1. RESULTS: Over 52% of women experienced at least one type of IPV, with 33.01%, 49.07%, and 8.99% experiencing emotional, physical, and sexual violence, respectively. The regression results show that armed conflicts were significantly and positively associated with the experience of all types of IPV. In addition, the association between armed conflicts and the experience of emotional IPV was positively moderated by women's attitudes towards IPV. CONCLUSION: Our findings suggest that women living in high-conflict regions were more prone to experience IPV, particularly women with positive attitudes towards IPV. Promoting progressive gender roles, women's empowerment, awareness of IPV and inclusion of women in conflict resolution will help deal with the issue of IPV.


Asunto(s)
Violencia de Pareja , Humanos , Femenino , Afganistán , Estudios Transversales , Violencia , Conflictos Armados , Prevalencia , Factores de Riesgo , Parejas Sexuales/psicología
15.
Am J Nurs ; 124(5): 15-17, 2024 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-38661692
16.
Artículo en Inglés, Español | MEDLINE | ID: mdl-38677942

RESUMEN

OBJECTIVE: To characterise social determinants of health, mental health problems and potentially problematic symptoms in the adult population displaced by internal armed conflict in Colombia. METHODS: Cross-sectional descriptive study with a random sample of 98 adults forcefully displaced to Soacha, Colombia, due to internal armed conflict. The Self Report Questionnaire to detect potentially problematic mental health problems and symptoms, and a structured questionnaire on social determinants of health were applied. RESULTS: The median age was 38 [interquartile range, 28-46] years, and women predominated (69.39%). The median time since displacement was 36 [16-48] months, and time since settlement in Soacha, 48 [5-48] months. 86.32% survived on less than the minimum wage per month and 93.87% did not have an employment contract. 42.86% and 7.14% reported being owners of their homes before and after displacement, respectively. Upon arriving in Soacha, 79.60% went to primary support networks and 3% to institutions. Before displacement, 16.33% lacked health insurance and 27.55% afterwards. Regarding mental health problems; there were possible depressive or anxious disorders in 57.29%; possible psychosis in 36.73%; and potentially problematic symptoms in 91.66%, being more prevalent and serious in women (p = 0.0025). CONCLUSIONS: A deterioration in living conditions and a higher prevalence of potentially problematic mental health problems and symptoms was reported in displaced adult populations settled in Soacha compared to other regions of the country. Analyses with complementary perspectives are required to evaluate these differences.


Asunto(s)
Conflictos Armados , Trastornos Mentales , Refugiados , Determinantes Sociales de la Salud , Humanos , Colombia/epidemiología , Femenino , Adulto , Masculino , Estudios Transversales , Persona de Mediana Edad , Conflictos Armados/psicología , Trastornos Mentales/epidemiología , Refugiados/psicología , Refugiados/estadística & datos numéricos , Encuestas y Cuestionarios , Adulto Joven
17.
Health Res Policy Syst ; 22(1): 55, 2024 Apr 30.
Artículo en Inglés | MEDLINE | ID: mdl-38689347

RESUMEN

BACKGROUND: Maternal and neonatal mortality remains a major concern in the Democratic Republic of Congo (DRC), and the country's protracted crisis context exacerbates the problem. This political economy analysis examines the maternal and newborn health (MNH) prioritization in the DRC, focussing specifically on the conflict-affected regions of North and South Kivu. The aim is to understand the factors that facilitate or hinder the prioritization of MNH policy development and implementation by the Congolese government and other key actors at national level and in the provinces of North and South Kivu. METHODS: Using a health policy triangle framework, data collection consisted of in-depth interviews with key actors at different levels of the health system, combined with a desk review. Qualitative data were analysed using inductive and then deductive approaches, exploring the content, process, actor dynamics, contextual factors and gender-related factors influencing MNH policy development and implementation. RESULTS: The study highlighted the challenges of prioritizing policies in the face of competing health and security emergencies, limited resources and governance issues. The universal health coverage policy seems to offer hope for improving access to MNH services. Results also revealed the importance of international partnerships and global financial mechanisms in the development of MNH strategies. They reveal huge gender disparities in the MNH sector at all levels, and the need to consider cultural factors that can positively or negatively impact the success of MNH policies in crisis zones. CONCLUSIONS: MNH is a high priority in DRC, yet implementation faces hurdles due to financial constraints, political influences, conflicts and gender disparities. Addressing these challenges requires tailored community-based strategies, political engagement, support for health personnel and empowerment of women in crisis areas for better MNH outcomes.


Asunto(s)
Conflictos Armados , Política de Salud , Prioridades en Salud , Salud del Lactante , Salud Materna , Humanos , República Democrática del Congo , Recién Nacido , Femenino , Embarazo , Mortalidad Infantil , Cobertura Universal del Seguro de Salud , Política , Servicios de Salud Materna/economía , Mortalidad Materna , Lactante , Formulación de Políticas , Masculino , Accesibilidad a los Servicios de Salud , Investigación Cualitativa , Servicios de Salud Materno-Infantil/economía , Gobierno
19.
JAMA Netw Open ; 7(3): e242091, 2024 Mar 04.
Artículo en Inglés | MEDLINE | ID: mdl-38477917

RESUMEN

Importance: Protracted wars, which disproportionately affect low-resource countries, exacerbate the challenges faced by cancer care systems, with lung cancer being the most affected as the most fatal oncological condition. Objective: To characterize the presentation and survival of patients with lung cancer during the decade-long Syrian war. Design, Setting, and Participants: This cohort study included patients at a large oncology center in Syria during the first 8 years of the Syrian armed conflict (2011-2018). All patients with a new diagnosis of lung cancer were included. Variables investigated included histological subtypes, TNM classification (tumor, lymph nodes, and metastasis), and staging at diagnosis as well as the yearly follow-ups up to 5 years after presentation. Exposure: The Syrian war divided the country into temporary regions with different political influences and heterogeneously impacted health care accessibility among these regions. Main Outcomes and Measures: Change in prevalence of advanced lung cancer cases at presentation; change in overall survival odds. Results: The study included 5160 patients from all Syrian governorates (mean [SD] age, 59.6 [10.8] years; 4399 men [85.3%]). New diagnoses sharply declined during the first 3 years of the war, with partial recovery afterward. Regardless of their tempo-geographical regions, 60% to 80% of the yearly diagnoses presented with metastases. The 1-year and 5-year survival rates were 13.1% (423 of 3238 patients with follow-up results) and 0.1% (2 of 1853 patients), respectively. Patients who presented from regions more involved in the armed conflicts showed poorer survival rates with odds ranging between 0.51 (95% CI, 0.44-0.59) and 0.61 (95% CI, 0.49-0.74) across follow-ups for up to 2 years in comparison with patients presenting from safer regions. War-related health care inaccessibility explained a greater percentage of the variability in survival (Nagelkerke R2 = 7.5%; P < .001) than both patients' age and the stage of the disease combined (Nagelkerke R2 = 3.9%; P < .001). Conclusions and Relevance: The Syrian war has been associated with a marked decline in the management of patients with lung cancer, with limited access to specialized care, delayed diagnoses, and substantial decrease in survival rates correlating with the intensity of armed conflict in the respective regions. The profound repercussions of the prolonged armed conflict on patients with lung cancer in Syria necessitates urgent comprehensive strategies to improve the accessibility and quality of health care services, especially in conflict-ridden zones.


Asunto(s)
Neoplasias Pulmonares , Masculino , Humanos , Persona de Mediana Edad , Siria , Estudios de Cohortes , Conflictos Armados , Cabeza
20.
JAMA ; 331(7): 621, 2024 02 20.
Artículo en Inglés | MEDLINE | ID: mdl-38497703
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