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Contusión Encefálica , Neoplasias Meníngeas , Meningioma , Neoplasias de la Base del Cráneo , Humanos , Meningioma/cirugía , Contusión Encefálica/cirugía , Neoplasias Meníngeas/cirugía , Neoplasias de la Base del Cráneo/cirugía , Base del Cráneo/cirugía , Factores de Riesgo , Estudios Retrospectivos , Procedimientos Neuroquirúrgicos/efectos adversosAsunto(s)
Contusión Encefálica , Lesiones Traumáticas del Encéfalo , Hipertensión Intracraneal , Humanos , Lesiones Traumáticas del Encéfalo/complicaciones , Lesiones Traumáticas del Encéfalo/cirugía , Encéfalo , Contusión Encefálica/cirugía , Lóbulo Temporal/cirugía , Presión Intracraneal , Monitoreo FisiológicoRESUMEN
PURPOSE: Placement of a subdural drain after burr-hole drainage of chronic subdural hematoma (cSDH) significantly reduces risk of its recurrence and lowers mortality at 6 months. Nonetheless, measures to reduce morbidity related to drain placement are rarely addressed in the literature. Toward reducing drain-related morbidity, we compare outcomes achieved by conventional insertion and our proposed modification. METHODS: In this retrospective series from two institutions, 362 patients underwent burr-hole drainage of unilateral cSDH with subsequent subdural drain insertion by conventional technique or modified Nelaton catheter (NC) technique. Primary endpoints were iatrogenic brain contusion or new neurological deficit. Secondary endpoints were drain misplacement, indication for computed tomography (CT) scan, re-operation for hematoma recurrence, and favorable Glasgow Outcome Scale (GOS) score (≥ 4) at final follow-up. RESULTS: The 362 patients (63.8% male) in our final analysis included drains inserted in 56 patients by NC and 306 patients by conventional technique. Brain contusions or new neurological deficits occurred significantly less often in the NC (1.8%) than conventional group (10.5%) (P = .041). Compared with the conventional group, the NC group had no drain misplacement (3.6% versus 0%; P = .23) and significantly fewer non-routine CT imaging related to symptoms (36.5% versus 5.4%; P < .001). Re-operation rates and favorable GOS scores were comparable between groups. CONCLUSION: We propose the NC technique as an easy-to-use measure for accurate drain positioning within the subdural space that may yield meaningful benefits for patients undergoing treatment for cSDH and vulnerable to complication risks.
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Contusión Encefálica , Hematoma Subdural Crónico , Humanos , Masculino , Femenino , Estudios Retrospectivos , Hematoma Subdural Crónico/diagnóstico por imagen , Hematoma Subdural Crónico/cirugía , Espacio Subdural/cirugía , Trepanación/efectos adversos , Trepanación/métodos , Drenaje/efectos adversos , Drenaje/métodos , Contusión Encefálica/cirugía , Catéteres , Resultado del Tratamiento , RecurrenciaRESUMEN
Background: Though frontal lobe contusion is a major cause for morbidity and prolonged hospitalization following excision of anterior skull base meningiomas, there is only limited literature on this complication. This study aimed to find out the incidence of postoperative frontal lobe contusion, identify the risk factors for its development and its impact on early postoperative outcome. Methods: Data from 110 patients who underwent excision of anterior skull base meningiomas through a unilateral supraorbital craniotomy from 2001 to 2018 were retrospectively analyzed. The risk factors analyzed for development of postoperative contusion were tumor location, size, volume, peritumoral edema, tumor consistency, extent of resection, tumor grade and type of retraction used. Results: Simpson grade II excision was achieved in ninety-two patients (83.6%). There was no frontal lobe contusion in eighty-two patients (74.5%). Frontal lobe contusion was noted in twenty-eight patients (25.5%), but was severe in only four patients (3.6%). On multivariate analysis, fixed retractor use (OR 11.56 [1.21-110.03]; P =0.03) and WHO grade II tumor (OR 3.29 [1.11-9.77]; P =0.03) were independently associated with postoperative frontal lobe contusion. Patients with higher contusion grade had significantly longer postoperative hospitalization (P =.02) and lower KPS score at discharge (P =.01). Conclusions: Unilateral supraorbital craniotomy and lateral subfrontal approach is an excellent procedure for excision of anterior skull base meningiomas with minimal postoperative complications related to frontal lobe retraction. Frontal lobe contusion should be avoided with the use of dynamic retraction, since postoperative contusion prolongs hospitalization and worsens the functional outcome at discharge.
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Contusión Encefálica , Neoplasias Meníngeas , Meningioma , Neoplasias de la Base del Cráneo , Humanos , Meningioma/patología , Neoplasias Meníngeas/cirugía , Neoplasias Meníngeas/etiología , Neoplasias de la Base del Cráneo/cirugía , Neoplasias de la Base del Cráneo/patología , Estudios Retrospectivos , Contusión Encefálica/etiología , Contusión Encefálica/cirugía , Procedimientos Neuroquirúrgicos/efectos adversos , Procedimientos Neuroquirúrgicos/métodos , Factores de Riesgo , Base del Cráneo/cirugía , Base del Cráneo/patología , Resultado del TratamientoRESUMEN
BACKGROUND: Falls are common for persons of advanced age and can result in severe traumatic brain injury (TBI). The purpose of the present study was to determine the survival benefit from aggressive operative intervention. METHODS: The trauma quality improvement program database from 2013 to 2016 was accessed for the present study. All patients aged 80-89 years who had sustained a severe TBI with a Glasgow coma scale (GCS) score of ≤8 and brain abbreviated injury scale score of ≥3 and had undergone operative intervention (craniotomy or craniectomy) were included in the present study. The patients were divided into 2 groups, those who had survived and those who had died, and the characteristics, injury severity score (ISS), types of intracranial hemorrhage, and comorbidities were compared. Multivariable logistic regression analysis was performed to determine the factors associated with survival. A receiving operating characteristic curve was created to test the model, and the area under the curve was calculated. RESULTS: Of the 1266 patients who had met the inclusion criteria for the present study, only 477 (37.68%) had survived. A lower ISS, higher GCS score, and no history of coagulopathy were factors indicating a greater chance of survival. Operative intervention for epidural hematoma, brain contusion, and subdural hematoma was associated with 3.5, 2.25, and 1.86 odds of survival, respectively. Procedure type (craniectomy vs. craniotomy) did not affect the outcome. The area under the curve was 0.723 (95% confidence interval, 0.694-0.752). CONCLUSIONS: The octogenarians who had undergone craniotomy or craniectomy for severe TBI after a fall had very high mortality. A lower ISS, higher GCS score, no history of coagulopathy and evacuation of subdural hematoma, epidural hematoma, or brain contusion indicated a greater probability of survival.
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Contusión Encefálica , Lesiones Traumáticas del Encéfalo , Anciano de 80 o más Años , Contusión Encefálica/cirugía , Lesiones Traumáticas del Encéfalo/cirugía , Escala de Coma de Glasgow , Hematoma Subdural/cirugía , Humanos , Procedimientos Neuroquirúrgicos/métodos , Octogenarios , Estudios Retrospectivos , Resultado del TratamientoRESUMEN
Transcranial electrical stimulated motor-evoked potentials (tcMEPs) are widely used to evaluate motor function in humans, and even in animal studies, tcMEPs are used to evaluate neurological dysfunction. However, there is a dearth of reports on extended tcMEP recordings in both animal models and humans. Therefore, this study examined a new technique for stably recording tcMEPs over several weeks in six healthy female Sprague-Dawley rats. We thinned the skull bone using the skull base and spinal surgery technique to reduce electrical resistance for electrical stimulation. tcMEPs were recorded on days 1, 7, 14, 21, and 28 after surgery. The onset latency and amplitude of tcMEPs from the hindlimbs were recorded and evaluated, and histological analysis was performed. Stable amplitude and onset latency could be recorded over several weeks, and histological analysis indicated no complications attributable to the procedure. Thus, our novel technique allows for less invasive, safer, easier, and more stable extended tcMEP recordings than previously reported techniques. The presently reported technique may be applied to the study of various nerve injury models in rats: specifically, to evaluate the degree of nerve dysfunction and recovery in spinal cord injury, cerebral infarction, and brain contusion models.
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Potenciales Evocados Motores/fisiología , Cráneo/cirugía , Estimulación Transcraneal de Corriente Directa/métodos , Animales , Contusión Encefálica/diagnóstico , Contusión Encefálica/fisiopatología , Contusión Encefálica/cirugía , Infarto Cerebral/diagnóstico , Infarto Cerebral/fisiopatología , Infarto Cerebral/cirugía , Modelos Animales de Enfermedad , Electromiografía , Femenino , Miembro Posterior/fisiología , Humanos , Monitoreo Intraoperatorio/métodos , Procedimientos Neuroquirúrgicos/métodos , Ratas , Ratas Sprague-Dawley , Traumatismos de la Médula Espinal/diagnóstico , Traumatismos de la Médula Espinal/fisiopatología , Traumatismos de la Médula Espinal/cirugíaRESUMEN
BACKGROUND: Traumatic brain injury (TBI) is the most common neurosurgical condition globally. In Cameroon, there are 572 cases of TBI per 100,000 people, but <40% of Cameroonians live within 4 hours of a neurosurgical facility. We sought to understand the clinical outcomes at a neurosurgical center in Central Cameroon. METHODS: This cross-sectional study was conducted at the largest neurosurgical center of Cameroon, the Yaounde Central Hospital. Data included 100 consecutive patients undergoing an intervention 72 hours after their injury from February 1, 2015 to February 1, 2019. Patients with missing data or undergoing surgery >72 hours after injury were excluded. Analyses of covariance were performed, and a P value >0.05 was considered significant. A Kaplan-Meier survival curve was computed. RESULTS: The patients had a mean age of 31.3 ± 17.4 years, with a male predominance of 91.0%, and the principal mechanism of injury was road traffic accidents (68.0%). Only 11% arrived via ambulance, and 36.0% were admitted <3 hours after the traumatic event. The postoperative mortality was 15.0%, mean survival was 25.0 postoperative days (95% confidence interval, 23.42-26.52), and the mean Glasgow Outcome Scale score at 28 days was 3.9 ± 1.4. CONCLUSIONS: Most patients with TBI undergoing neurosurgery 72 hours after injury in Cameroon arrive at the hospital late and have a high mortality risk during the first postoperative week. Investments in prehospital care should be made to improve surgical outcomes.
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Ambulancias/estadística & datos numéricos , Lesiones Traumáticas del Encéfalo/cirugía , Traumatismos Craneocerebrales/cirugía , Craneotomía , Servicios Médicos de Urgencia , Mortalidad , Tiempo de Tratamiento/estadística & datos numéricos , Accidentes por Caídas/estadística & datos numéricos , Accidentes de Tránsito/estadística & datos numéricos , Adolescente , Adulto , Anciano , Contusión Encefálica/cirugía , Camerún , Niño , Preescolar , Estudios Transversales , Femenino , Escala de Coma de Glasgow , Escala de Consecuencias de Glasgow , Hematoma Epidural Craneal/cirugía , Hematoma Intracraneal Subdural/cirugía , Hospitalización , Humanos , Lactante , Masculino , Persona de Mediana Edad , Fractura Craneal Deprimida/cirugía , Tasa de Supervivencia , Resultado del Tratamiento , Violencia/estadística & datos numéricos , Adulto JovenRESUMEN
INTRODUCTION: Controlling of secondary traumatic brain injuries (TBI) is necessary due to its salient effect on the improvement of patients with TBI and the final outcomes within early hours of trauma onset. This study aims to investigate the effect of intravenous tranexamic acid (TAX) administration on decreased hemorrhage during surgery. METHODS: This double-blind, randomized, and placebo-controlled trial was conducted on patients referring to the emergency department (ED) with IPH due to brain contusion within 8 h of injury onset. The patients were evaluated by receiving TXA and 0.9% normal saline as a placebo. The following evaluation and estimations were performed: intracranial hemorrhage volume after surgery using brain CT-scan; hemoglobin (Hb) volume before, immediately after, and six hours after surgery; and the severity of TBI based on Glasgow Coma Score (GCS). RESULTS: 40 patients with 55.02 ± 18.64 years old diagnosed with a contusion and intraparenchymal hemorrhage. Although the (Mean ± SD) hemorrhage during surgery in patients receiving TXA (784.21 ± 304.162) was lower than the placebo group (805.26 ± 300.876), no significant difference was observed between two groups (P=0.83). The (Mean ± SD) Hb volume reduction immediately during surgery (0.07 ± 0.001 and 0.23 ± 0.02) and six hours after surgery (0.04 ± 0.008 and 0.12 ± 0.006) was also lower in TXA group but had no significant difference (P = 0.89 and P = 0.97, respectively). CONCLUSION: Using TXA may reduce the hemorrhage in patients with TBI, but this effect, as in this study, was not statistically significant and it is suggested that a clinical trial with a larger population is employed for further investigation.
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Antifibrinolíticos/administración & dosificación , Pérdida de Sangre Quirúrgica/prevención & control , Contusión Encefálica/cirugía , Hemorragia Encefálica Traumática/prevención & control , Ácido Tranexámico/administración & dosificación , Adulto , Anciano , Contusión Encefálica/complicaciones , Contusión Encefálica/tratamiento farmacológico , Hemorragia Encefálica Traumática/etiología , Hemorragia Encefálica Traumática/mortalidad , Método Doble Ciego , Femenino , Escala de Coma de Glasgow , Humanos , Infusiones Intravenosas , Masculino , Persona de Mediana Edad , Tasa de Supervivencia , Resultado del TratamientoRESUMEN
BACKGROUND: The optimal management strategy for cerebral contusion remains controversial, especially when standard craniotomy could not be used. We performed neuro-endoscopic target lesionectomy for the delayed progression of cerebral contusion in order to aspirate the necrotic core, which is the primal source of contusional edema. METHODS: The present study included 10 consecutive patients (2 women and 8 men, with a mean age of 67 years old) with traumatic brain injury presenting with delayed deterioration of cerebral contusion where standard craniotomy could not be used. Neuro-endoscopic aspiration of the necrotic core was prospectively performed for all patients. We assessed the computed tomography findings after surgery to evaluate the efficacy of this procedure. RESULTS: Endoscopic surgery was performed promptly after neurological deterioration, with a mean interval between trauma and surgery of 7 days, ranging from 2 to 16 days. During the operation, the centers of contusions comprised serous liquid components in all 10 patients and were easily aspirated by endoscopy. Contusional edemas were markedly decreased in all within 3 days after surgery. CONCLUSIONS: Progression of contusional edema can be caused by the accumulation of water into the necrotic core due to the rapid increase in osmolality. In light of the highly liquefied demarcated characteristics of the necrotic core, neuro-endoscopic aspiration could be an optional treatment strategy for cerebral contusion with delayed progression in a minimally invasive manner.
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Contusión Encefálica/cirugía , Craneotomía/métodos , Endoscopía/métodos , Succión/métodos , Adulto , Anciano , Contusión Encefálica/patología , Femenino , Humanos , Masculino , Persona de Mediana Edad , Necrosis , Tomografía Computarizada por Rayos X/métodosRESUMEN
OBJECTIVE: With the development of frontal contusion, patients may rapidly deteriorate or even die. Experience in the treatment of frontal contusion in high-altitude regions is limited; thus, we explore a grading system for the treatment of frontal lobe contusion. METHODS: A total of 446 patients with frontal contusions in a high-altitude regions were reviewed retrospectively. We combined the patients' computed tomography scans of the head and clinical features for grading. The score determined the treatment and whether the bone flap was removed. If the patient's condition deteriorated, and the score was greater than 1, the patient was treated surgically. At the same time, the risk factors of deterioration were analyzed. Finally, the Glasgow Outcome Scale of conservative treatment and surgical treatment groups was analyzed. RESULTS: Among the 446 patients, 254 were conservatively treated, and 28 worsened and underwent surgical treatment. In total, 122 patients received an operation. Logistic regression analysis indicated that scattered hematoma, anterior angle of the ventricle, and hemoglobin concentration were risk factors. The postoperative Glasgow Outcome Scale of conservative treatment and surgical treatment groups was analyzed; the good healing rate of the conservative treatment group was 91.12%, the good healing rate of the retain-bone flap surgical group was 75%, and the good healing rate of the remove-bone flap surgical group was 63.33%. The failure rates of the groups were 9.38% and 7.78%, respectively. CONCLUSIONS: This grading system could guide frontal contusion treatment, which could help patients to achieve a good healing rate and reduce the failure rate.
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Altitud , Contusión Encefálica/diagnóstico , Contusión Encefálica/cirugía , Lóbulo Frontal/lesiones , Procedimientos Neuroquirúrgicos/métodos , Evaluación de Resultado en la Atención de Salud , Adulto , Contusión Encefálica/terapia , Femenino , Lóbulo Frontal/diagnóstico por imagen , Escala de Coma de Glasgow , Humanos , Masculino , Estudios Retrospectivos , Tomografía Computarizada por Rayos XRESUMEN
OBJECTIVE: To investigate clinical efficacy of and optimal therapeutic strategy for ventricular intracranial pressure monitoring (V-ICPM) in patients with traumatic bifrontal contusions (TBCs). METHODS: From 8760 patients with traumatic brain injury treated between January 2010 and January 2016, a retrospective analysis was performed on 105 patients with TBCs who underwent V-ICPM and 282 patients with TBCs who did not. All patients underwent treatment at the 101st Hospital of PLA, Wuxi, China. Rates of successful conservative treatment, decompressive craniectomy, and bifrontal craniotomy; incidence of neurologic dysfunction; length of stay; and medical expenses were compared between groups. RESULTS: Glasgow Outcome Scale was used to assess all patients during follow-up (range, 6 months to 5.5 years). There were no significant differences in prognosis between the 2 groups (P = 0.100). Compared with the patients who did not undergo V-ICPM, the V-ICPM group had a significantly better successful conservative treatment rate (64.8% vs. 47.2%, P = 0.002), decompressive craniectomy rate (8.1% vs. 22.1%, P = 0.008), and bifrontal craniotomy rate (5.7% vs. 15.6%, P = 0.01); shorter length of stay (P = 0.000); and lower medical expenses (P = 0.004). CONCLUSIONS: Patients with TBCs should be strictly, closely, and dynamically observed by neurosurgery intensive care unit physicians and nurses. Patients should undergo ventricular intracranial pressure probe implantation in a timely manner. V-ICPM can help optimize treatment. Although V-ICPM did not significantly improve the prognosis of patients, it had many other advantages. V-ICPM warrants further clinical research and may be beneficial for patients with TBCs.
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Contusión Encefálica/diagnóstico por imagen , Contusión Encefálica/cirugía , Ventrículos Cerebrales/diagnóstico por imagen , Ventrículos Cerebrales/cirugía , Presión Intracraneal/fisiología , Monitorización Neurofisiológica Intraoperatoria/métodos , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Contusión Encefálica/fisiopatología , Lesiones Traumáticas del Encéfalo/diagnóstico por imagen , Lesiones Traumáticas del Encéfalo/fisiopatología , Lesiones Traumáticas del Encéfalo/cirugía , Ventrículos Cerebrales/fisiopatología , Niño , Craniectomía Descompresiva/métodos , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Adulto JovenRESUMEN
OBJECTIVES: We aimed to investigate the prevalence and pattern of cognitive dysfunction in patients with traumatic bifrontal contusions and their association with functional outcome. MATERIALS AND METHODS: We prospectively recruited patients with bifrontal contusions in a regional neurosurgical center in Hong Kong over a 2-year period. Functional outcome was assessed by modified Rankin Scale (mRS), and cognitive outcomes were assessed by Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MoCA), and a comprehensive neuropsychological battery. RESULTS: We recruited 34 patients with traumatic bifrontal contusions over a 2-year period. Nine (26%) patients had craniotomy for evacuation of left or right frontal contusions. Functional outcome using mRS was significantly correlated with cognitive outcomes using MMSE or MoCA. The effect of cognitive outcome using MMSE or MoCA persisted after adjustments of age, sex, admission Glasgow Coma Scale, and surgery. In patients who completed the comprehensive neuropsychological assessments, cognitive impairment in at least one of the neuropsychological tests was noted in 73% of them. CONCLUSIONS: Cognitive dysfunction had a significant impact on functional outcome, and treatment strategy should be developed to minimize them.
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Contusión Encefálica/psicología , Cognición , Disfunción Cognitiva/psicología , Lóbulo Frontal/lesiones , Adulto , Anciano , Contusión Encefálica/complicaciones , Contusión Encefálica/fisiopatología , Contusión Encefálica/cirugía , Disfunción Cognitiva/etiología , Disfunción Cognitiva/fisiopatología , Femenino , Lateralidad Funcional , Escala de Coma de Glasgow , Hong Kong , Humanos , Masculino , Pruebas de Estado Mental y Demencia , Persona de Mediana Edad , Pruebas Neuropsicológicas , Estudios ProspectivosRESUMEN
BACKGROUND: The current surgical treatment of choice for refractory intracranial hypertension after traumatic brain injury (TBI) is decompressive craniectomy. Despite efficacy in control of intracranial pressure (ICP), its contribution to an improved outcome is debatable. CASE DESCRIPTION: We describe a case of refractory intracranial hypertension successfully managed with cisternostomy. The rationale for this surgical technique is discussed, with a focus on the pathophysiologic processes underlying elevated ICP and its improvement after surgery. CONCLUSION: Cisternostomy proved to have an immediate effect in controlling ICP and improving brain oxygenation and metabolism.
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Contusión Encefálica/cirugía , Lesiones Traumáticas del Encéfalo/cirugía , Hipertensión Intracraneal/cirugía , Ventriculostomía/métodos , Edema Encefálico/cirugía , Humanos , Masculino , Persona de Mediana Edad , Resultado del TratamientoRESUMEN
We compared the surgical efficacy of the supraorbital key-hole approach (SKA) to conventional unilateral frontotemporal craniotomy (UFTC) for the treatment of patients with unilateral-dominant bilateral frontal contusions (BFCs). A retrospective analysis of 62 patients with unilateral-dominant BFCs who underwent surgery at our institute between 2014 and 2017 was performed. There were 26 patients who underwent SKA (group A) and 36 who underwent UFTC (group B). Postoperative computed tomography scans showed satisfactory evacuation of the frontal cerebral contusions in both groups (p > 0.05). There was less intraoperative blood loss in group A than group B (17.1 ± 4.55 vs. 67.6 ± 10.28 mL, p < 0.05). The operative time was also shorter in group A (82.7 ± 13.73 vs. 132.4 ± 9.17 min, p < 0.05). Postoperative bleeding occurred in three cases in group A and in only one case in group B (p > 0.05). The average length of hospitalization was shorter in group A than group B (7.3 ± 1.09 vs. 12.9 ± 1.71 days, p < 0.05). No differences in the Glasgow Outcome Scale were observed between the two groups after 6 months of follow-up (p > 0.05). Thus, compared to UFTC, SKA is associated with shorter operation times and less trauma to the surrounding brain tissue.
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Contusión Encefálica/patología , Contusión Encefálica/cirugía , Lóbulo Frontal/patología , Adulto , Anciano , Biomarcadores , Contusión Encefálica/diagnóstico , Craneotomía/métodos , Femenino , Lóbulo Frontal/diagnóstico por imagen , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Adulto JovenRESUMEN
Impact of the allogenic tissue transplantation of the fetal cerebral large hemispheres and the оlfactory bulb tissue (OBT) on the healing processes after the brain contusion was studied in experiment. The investigation was performed on mongrel male rats: in laboratory animals of the first group in the first day after open penetrating local cerebral trauma (OPLCT) the allogenic fetal nervous tissue fragment was transplanted into the formatted tissue defect; for the second group in the first day after cerebral trauma the allogenic OBT fragment was transplanted into the formatted tissue defect; and for the third group (control) - the OPLCT was done without further transplantation of tissues. The impact of the allogenic fetal nervous tissue transplantation was demonstrated by more active participation of glial cells during the healing process course, and the OBT transplantation was followed by activation of neoangiogenesis processes , mainly in the injured brain. The experimental simulation choosed permits to study the possibilities of application of neurogenic tissues in the brain contusion treatment, and to determine the therapy tactics.
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Contusión Encefálica/terapia , Trasplante de Tejido Fetal/métodos , Neovascularización Fisiológica , Bulbo Olfatorio/trasplante , Recuperación de la Función , Heridas Penetrantes/terapia , Animales , Animales no Consanguíneos , Contusión Encefálica/patología , Contusión Encefálica/cirugía , Feto , Histocitoquímica , Masculino , Neuroglía/citología , Neuroglía/fisiología , Neuronas/citología , Neuronas/fisiología , Bulbo Olfatorio/citología , Ratas , Trasplante Homólogo , Cicatrización de Heridas/fisiología , Heridas Penetrantes/patología , Heridas Penetrantes/cirugíaRESUMEN
We report on a case of catheter-related thrombosis after 7day catheter placement during intravascular temperature management (IVTM), in spite of the use of prophylactic anticoagulants. There were no clinical sequelae. According to the literature, occult thrombosis during ITVM could be more frequent than previously reported and dedicated monitoring for potential thrombosis may be indicated. However, a study comparing IVTM with surface cooling found no differences in clinical outcome. Therefore, n either of the methods can be recommended over the other. Further studies should evaluate the rate of occult thrombosis during the use of both cooling methods.
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Temperatura Corporal , Catéteres Venosos Centrales/efectos adversos , Trombosis/etiología , Adulto , Vasos Sanguíneos , Contusión Encefálica/fisiopatología , Contusión Encefálica/cirugía , Cateterismo Venoso Central , Humanos , Masculino , Procedimientos NeuroquirúrgicosRESUMEN
OBJECTIVE: The study aimed to investigate optimal surgical timing, methods, and clinical efficacy of bifrontal decompression craniotomy (BDC) on traumatic bifrontal contusions (TBC). METHODS: A retrospective analysis was performed of 98 patients with TBC who underwent BDC of 2510 patients with traumatic brain injury. The operation-timing score was used to determine surgical timing. RESULTS: Ninety-eight cases (19%) underwent amended BDC. Initial Glasgow Coma Score was 13-15 in 52 cases (61%). Initial computed tomography showed hematoma volumes of 15.1 ± 5.2 mL in 73 cases (74%). Preoperative hematoma (80.2 ± 20.5 mL; P < 0.05) was significantly enlarged. Fluctuation in the surgery-timing curve is timing for surgery. Average operation time was 4.5 ± 3.4 days after admission. Hematoma was totally evacuated and Glasgow Coma Score significantly increased (P < 0.05) in all cases. In the follow-up Glasgow Outcome Score, 79 patients (81%) recovered well. CONCLUSIONS: TBC progressed gradually and deteriorated rapidly; this should be strictly and dynamically observed, and patients should be operated on in a timely manner. Changing the operation-timing score is the gold standard for surgery. Amended BDC can significantly improve the prognosis of patients.
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Contusión Encefálica/mortalidad , Contusión Encefálica/cirugía , Craniectomía Descompresiva/mortalidad , Hematoma Epidural Craneal/mortalidad , Hematoma Epidural Craneal/cirugía , Tempo Operativo , Complicaciones Posoperatorias/mortalidad , Adulto , China/epidemiología , Comorbilidad , Craniectomía Descompresiva/estadística & datos numéricos , Femenino , Humanos , Masculino , Complicaciones Posoperatorias/prevención & control , Prevalencia , Estudios Retrospectivos , Factores de Riesgo , Tasa de Supervivencia , Resultado del TratamientoRESUMEN
Retrospective analysis of craniocerebral trauma (CCT) in 141 injured persons, ageing (38.3 ± 14.3) yrs at average, severity of which in accordance to Glasgow scale was estimated in 13 15 points, was performed. The injured persons were managed in accordance to actual recommendations of Ministry of Health of Ukraine. In accordance to CT data, the brain commotion was noted in 40 patients, the brain contusion type Ð in 25, the brain contusion type ÐÐ with the skull fornix fracture in 30, with linear fracture of the skull bones and traumatic hematomas into the braintunics in 30, with fracture of the temporal bone pyramid in 16. In indices 14 points and less (in accordance to Glasgow scale) in terms up to 24 h after CCT and absence of alcohol intoxication in 76.9% injured persons in accordance to CT data the intracranial traumatic affections were revealed. In indices of 15 points in 21% of injured persons falsenegative results were determined, witnessing disparity of CCT signs with a CT data.