Natal and neonatal teeth: early diagnosis and management.

The eruption of teeth in newborns is a rare disorder of the oral cavity and are called 'natal teeth' when they are present at birth or 'neonatal teeth' when they erupt within the first month of life. In most of these cases, they are prematurely erupted deciduous teeth or supernumerary teeth. Supportive management should be given, to facilitate child's feeding and to prevent further complications, such as aspiration as the tooth could be mobile. This study describes a series of cases that were reported to our department, involving teeth located in the mandibular anterior region either at birth or within a few days after birth. The choice of treatment for each child was based on individual assessment of the case, considering options such as monitoring and extraction along with their associated complications.

Worldwide prevalence of natal and neonatal teeth: Systematic review and meta-analysis.

BACKGROUND: Identifying the presence of teeth in newborns is important as it may require immediate care. This study aimed to determine the worldwide prevalence of natal and neonatal teeth. TYPE OF STUDIES REVIEWED: Six electronic databases and the gray literature were searched on February 23, 2023 to identify observational studies reporting the prevalence of natal or neonatal teeth. Studies assuming natal and neonatal teeth as identical terms or not reporting prevalence indicators were excluded. The methodological quality of the studies was assessed using the Joanna Briggs Institute checklist for studies reporting prevalence data. The worldwide prevalence of natal and neonatal teeth was estimated via proportion meta-analysis using a ß-binomial model. Heterogeneity across studies was explored via subgroup analyses and meta-regression. RESULTS: None of the 23 included studies fulfilled all items of the methodological quality checklist. The worldwide prevalence of natal teeth was 34.55 (95% CI, 20.12 to 59.26) per 10,000, and the prevalence of neonatal teeth was 4.52 (95% CI, 2.59 to 17.91) per 10,000. Subgroup analysis by continent showed that the prevalence of natal teeth ranged from 11.26 (95% CI, 7.58 to 16.61) per 10,000 in Asia through 75.32 (95% CI, 51.11 to 99.86) per 10,000 in North America, and the prevalence of neonatal teeth ranged from 3.52 (95% CI, 1.73 to 7.06) per 10,000 in Europe through 6.01 (95% CI, 2.25 to 16.60) per 10,000 in South America. Meta-regression did not find a statistically significant association between prevalence rates and year of publication or sample size. PRACTICAL IMPLICATIONS: Approximately 1 in 289 newborns had natal teeth and 1 in 2,212 had neonatal teeth. Although this is not a high prevalence, professionals must be alert to identify these conditions, which often require immediate care.

Natal and neonatal teeth: a review and case series.

Natal and neonatal teeth are a relatively rare but well-documented phenomenon, with the majority being prematurely erupted teeth of the normal primary dentition. Related complications include feeding issues, traumatic lingual ulceration and risk of aspiration. We present three clinical cases referred to the Paediatric Dentistry Department at Guy's and St Thomas' NHS Foundation Trust and their management. Treatment choice is based on individual assessment of each patient and options include monitoring, smoothing of the teeth or extraction. General dental practitioners should be able to diagnose natal and neonatal teeth and provide initial management in primary care, with referral to secondary care services in more complex cases or those which are likely to require extraction.

Manejo conservador e intervención mínima en pacientes con dientes natales y neonatales: reporte de cuatro casos / Manejo conservador e intervenção mínima em pacientes com dentes natais e neonatais: Relato de quatro casos / Conservative management and minimal intervention in patients with natal and neonatal teeth: Report of four cases

Los dientes natales y neonatales están presentes al momento del nacimiento o en el primer mes de vida respectivamente. Son observados más frecuentemente en los incisivos centrales inferiores, y la mayoría de los casos estos dientes representan los dientes primarios. Las características clínicas, posibles complicaciones y el curso clínico son parámetros a considerar para un adecuado manejo. Sin embargo diferentes reportes afirman que pueden ocurrir complicaciones después de realizar la extracción en recién nacidos. A la fecha, no se han documentado reportes de casos en la literatura describiendo complicaciones en los dientes que se conservan como lo es la aspiración de los dientes. El objetivo del presente estudio es presentar cuatro casos, tres de los cuales fueron tratados con un manejo conservador. Considerando que la prevalencia ha incrementado progresivamente en los últimos años, neonatologos y odontopediatras deben hacer un diagnóstico temprano y ofrecer un adecuado tratamiento, brindando un bienestar general y oral en cada paciente. El éxito del tratamiento depende de un seguimiento periódico.

Os dentes natais e neonatais estão presentes no nascimento ou no primeiro mês de vida, respectivamente. Eles são vistos com mais frequência nos incisivos centrais inferiores e, na maioria dos casos, esses dentes representam os dentes decíduos. As características clínicas, as possíveis complicações e o curso clínico são parâmetros a serem considerados para um manejo adequado. Porém, diferentes relatos afirmam que complicações podem ocorrer após a realização da extração em recém-nascidos. Até o momento, não há relatos de casos documentados na literatura descrevendo complicações em dentes preservados, como aspiração dentária. O objetivo deste estudo é apresentar quatro casos, três dos quais foram tratados com conduta conservadora. Considerando que a prevalência tem aumentado progressivamente nos últimos anos, os neonatologistas e odontopediatras devem fazer o diagnóstico precoce e oferecer tratamento adequado, proporcionando bem-estar geral e bucal a cada paciente. O sucesso do tratamento depende de monitoramento regular.

Natal and neonatal teeth are present at birth or in the first month of life. They are observed more frequently in the mandibular central incisors, and in most cases, these teeth represent the true primary teeth. Clinical characteristics, possible complications and the clinical course are parameters to consider for proper management. Nevertheless, different reports argue that complications may occur after extraction in newborns. To date, there are no documented cases reported in the literature describing complications in retained teeth, such as aspiration of a tooth. The objective of the present study is to introduce four cases, three of which were treated with conservative management. Considering that the prevalence has increased progressively in recent years, neonatologists and pediatric dentists must make an early diagnosis and offer adequate treatment, providing general and oral wellness for each patient. The success of the treatment depends on periodic follow-up.

Dental Management of Congenital Granular Cell Lesion and Neonatal Teeth: A Case Report.

Congenital granular cell lesion (CGCL) is a rare benign oral cavity tumor in infants. Neonatal teeth are also rare dental anomalies that appear during the first month of life. This report describes a case of eruption of neonatal teeth after surgical excision of CGCL. Surprisingly, residual neonatal teeth erupted after extraction of the neonatal teeth. If neonatal teeth are mobile, they should be carefully extracted with curettage of the underlying tissues of the dental papilla; failure to curette the socket might result in eruption of odontogenic remnants. If neonatal teeth were exfoliated, parents should be informed of the need for regular checkups with a dentist due to possibility of development of residual neonatal teeth.

Oral Reactive Lesions Associated to Incomplete Removal of Natal Teeth: Case Report.

Natal teeth are infrequent at birth. Dental extraction is the most recommended treatment to avoid complications. Reactive soft tissue lesions associated to natal tooth or its incomplete removal are rare. A five-month-old female presented natal teeth #71 and #81 which were removed the day after the birth. The baby evolved with two nodules in the region of #71 and #81, pedunculated, 10 and 9 mm, respectively, covered by a pink mucosa, firm in consistency. Periapical radiography showed two radiopaque areas, suggestive of root fragments. After 30 days the nodule located in the region of #81 became purple in color and ulcerated. Both lesions were removed with high intensity diode laser. Histopathological analysis was compatible with inflammatory fibrous hyperplasia (#71) and pyogenic granuloma (#81). Early diagnosis of oral lesions in newborns by means of histopathological examination and a minimum invasive treatment, such as laser surgery, should be of primary concern.

Riga-Fede disease: A systematic review and report of two cases.

AIM: The term Riga-Fede disease has been used historically to describe traumatic ulceration that occurs on the ventral surface of tongue, buccal mucosa, gum or floor of the tongue in newborns and infants. It is most often associated with natal and neonatal teeth in newborns. The painful symptoms may be absent or acute, up to the point of preventing the baby from feeding. The aim of this work is to offer a description of the therapeutic solutions for the treatment of this pathological condition, with a review of the literature and the report of two cases. MATERIALS: A systematic review of the literature of articles presenting Riga-Fede Disease associated with natal and neonatal teeth was performed following the PRISMA protocol (Prefered Reporting Items for Systematic Reviews and Meta-Analyses). This bibliographic search was performed through two databases, PubMed and Google Scholar. CONCLUSION: Extraction and ameloplasty are the most effective treatments in the resolution of the Riga-Fede disease associated with natal/neonatal teeth. In the case of high dental mobility, resulting in an increased risk of exfoliation and possible tooth ingestion/inhalation, extraction is the therapeutic treatment of choice. When nutrition is not compromised, ameloplasty is the treatment of choice, as it is less invasive and more conservative.

Neonatal teeth: Importance of histological findings in management update.

BACKGROUND: Presence of teeth in a newborn represents a rare finding and a disturbance of biological chronology of teeth. The aim of this paper is to report two cases with neonatal teeth histologically examined. CASE REPORT: In this paper two cases of patients with neonatal teeth are reported and histological examinations of three extracted teeth are described. We report an exceptional finding in one of the neonatal teeth microscopically examined: a massive inflammatory infiltration in the pulp tissue similar to that in pulpitis. RESULTS: The management of natal and neonatal teeth usually includes the extraction in case of ulceration on the tongue or severe tooth mobility to prevent accidental inhalation or feeding disturbances. The presence of an inflammatory infiltration of pulp tissue in one of teeth histologically examined suggests to review the indications for extraction considered to date. CONCLUSION: The management of natal and neonatal teeth should consider the presence of an inflammatory infiltration of pulp tissue. An anamnestic interview is advisable in ordert to deeply investigate about possible behaviours of the child due to pain or discomfort.

Natal teeth: report of two cases.

Presence of teeth at birth or within a month post-delivery is a rare condition. We report here 2 cases to highlight their clinical features and discuss their possible treatment. A 7- days old female newborn with two mandibular central incisors, noticed by the parents at birth, with complaint of continuous crying, inability to suck milk and causing discomfort to the mother. The left incisor was highly mobile justifying its extraction. The second case was a female newborn referred 2 hours after delivery, for a brownish highly mobile mandibular incisor noticed by the pediatrician. Extraction was immediately made to avoid the danger of aspiration. This phenomenon can lead to complications either local such as pain on suckling or general such as undernutrition or asphyxia by aspiration. The decision to maintain or remove these teeth should be assessed in each case independently, based on degree of mobility and interference with breastfeeding.

Accidental displacement of primary anterior teeth following extraction of neonatal teeth.

Eruption of the first tooth at 6 months of age is a significant stage in a child's life. However, the presence of a tooth in the oral cavity of a newborn can lead to a lot of delusions. Natal and neonatal teeth are of utmost importance not only to a dentist but also for a pediatrician due to parental anxiety, folklore superstitions, and numerous complications associated with it. The present case report describes a 1.5 cm × 1.5 cm, slow-growing, soft-tissue gingival mass which developed following the extraction of a tooth-like structure in a 4-month-old male patient. Histological examination revealed that it contained a tooth-like hard tissue intermingled with bone and fibrous tissue. Based on clinical and histological findings, the present case was diagnosed as gingival hyperplasia with displaced tooth buds of 71 and 81, which might be due to chronic irritation or traumatic extraction of the neonatal teeth. No abnormal recurrence of the lesion was detected during the follow-up period. However, postoperative clinical and radiographic photographs further reconfirmed the absence of tooth in relation to 71 and 81.

Effectiveness of an Oral Health Education Program to Improve Mothers Awareness of Natal Teeth: A Randomized Controlled Study

Abstract Objective: To evaluate the effectiveness of an oral health talk aided by a video on improving the awareness of mothers about natal teeth in two rural communities in southwest Nigeria. Material and Methods: A cluster-randomized controlled trial was conducted among 80 mothers in two rural communities in Nigeria, randomized into study and control groups. Baseline information was obtained with a pre-tested interviewer administered questionnaire. The mothers in the study group participated in an oral health education program comprising of a video show on natal teeth in addition to an oral health talk. The control group did not receive any intervention. Post-intervention data was obtained three weeks afterwards. Data collected was analyzed with SPSS using paired t-test, independent t-test and Chi-square test. Results: The sociodemographic characteristics of participants in both groups were similar. The mean knowledge, attitude and practice percentage scores for the study group were 38.9 ± 26.3% (pre-intervention) and 73.6 ± 26.2% (post-intervention); while for the control group, the values were 43.2 ± 31.4% (pre-intervention) and 43.9 ± 32.4% (post-intervention). The study group, had a 34% increase in knowledge, attitude and practice percentage score (CI=23.7-45.5; t=6.4; p<0.001), while the control group, had an increase of 0.7% (CI=-0.7-2.2; t=1.00; p=0.323). Conclusion: An oral health education program comprising of oral health talk and a video about natal teeth improved the awareness of mothers about natal teeth as a normal phenomenon.

A comprehensive survey of natal and neonatal teeth in newborns.

OBJECTIVE: To evaluate clinical and histological characteristics and determine the incidence of natal/neonatal teeth in a large Turkish population. SUBJECTS AND METHODS: Among 17,829 newborns, who were hospitalized at the Neonatal Clinic of a governmental Children's Hospital between 2005 and 2011, 27 neonates were diagnosed with erupted teeth, which were examined in terms of location, clinical appearance and mobility. Besides histological evaluation, a positive family history was also recorded. The variables were analyzed using Chi-square test. RESULTS: Thirty-two natal/neonatal teeth were observed in 27 infants. The incidence of both natal and neonatal teeth was found to be 1:660, while the incidences were separately recorded as 1:1,048 and 1:1,782, respectively. The histological examination revealed a thin hypoplastic enamel layer and a normal dentin layer. There was no difference between the two genders in terms of natal/neonatal tooth type, positive family history and tooth morphology (p > 0.05); or between normal and conical shapes with regard to natal/neonatal tooth type, positive family history and tooth color (p > 0.05). CONCLUSIONS: This study exhibited a higher incidence in natal teeth than neonatal teeth. Macroscopic features were not found to be positively related to gender and tooth type.

Literature review and micro-computed tomography analysis of natal teeth: A pilot study.

AIM: To outline the current literature surrounding natal teeth, and then, in a pilot study, to evaluate natal teeth using micro-computed tomography (micro-CT) to determine their anatomical profile, and compare and contrast different analytical methods to assess natal teeth. METHODS: 2 extracted natal teeth (mandibular central incisors) and 1 exfoliated mandibular primary central incisor were subjected to micro-CT analysis. RESULTS: Within natal teeth, there were no statistical differences in tooth mineral density (TMD) of both enamel and dentine (P > .05), whereas mandibular primary central incisors had a significantly higher TMD of both enamel and dentine in comparison with both natal tooth 1 and natal tooth 2 (P < .05). Mandibular primary central incisors had a greater thickness and volume of both enamel and dentine, but exhibited lower pulpal space volume. CONCLUSION: Micro-CT is an alternative and non-invasive method to anatomically assess natal teeth. According to the pilot study, natal teeth exhibited lower TMD, decreased enamel and dentine thickness, and smaller pulpal space volume in comparison with mandibular primary incisor teeth. This pilot study creates a foundation to establish the collection and analysis of natal teeth on a larger scale over time using micro-CT.

Riga-Fede Disease Associated with Syndactyly and Oligodactyly: A rare Occurrence.

Background: Eruption of first primary tooth starts on an average at around six to seven months of age. Presence of teeth at birth or within a month after birth is considered rare. Natal teeth are those present in the oral cavity at the time of birth. These teeth can cause ulcers on the ventral surface of the tongue, lip, and the mother's breast characterizing the Riga Fede Disease. Exact aetiology of natal and neonatal teeth is still unclear. The treatment depends on its mobility of teeth as it is associated with the risk of aspiration or swallowing, whether the natal tooth is supernumerary or primary, causing any problems in breast feeding, presence of soft tissue injuries on tongue of the child or mother's breast and overall health of child. Case presentation: A fifteen day old girl reported with large ulceration on ventral surface of tongue due to sharp natal teeth present at mandibular anterior region which was also associated with feeding difficulties. Along with Riga Fede disease Syndactyly and Oligodactyly in left and right legs respectively was also observed. Extraction of the teeth has been carried out and complete healing of ulceration has been achieved within 30 days. Conclusion: The present case report describes a rare occurrence of Riga Fede disease with Syndactyly and Oligodactyly and highlights its symptomatology and therapeutic approach.

Oral Anomalies In Newborns: An Observational Cross-Sectional Study.

Purpose: To determine the prevalence of oral anomalies in newborns and the influence of maternal and neonatal factors on the development of these anomalies.
Methods: Four hundred newborns were included in the study conducted at the Hospital and Maternity Dom Orione (HMDO) in the city of Araguaína, Tocantins, Brazil. After collecting demographic data and information about the newborns from the medical records, an oral examination was performed by a single examiner.
Results: The prevalence of oral anomalies was 50 percent. Cysts of the oral cavity were the most prevalent anomalies (43 percent), with palatine cysts (26 percent) and alveolar cysts (23 percent) being the most common. Ankyloglossia was present in nine percent of newborns, and congenital eruption cysts and neonatal teeth were present in 0.5 percent and 0.2 percent, respectively. No statistically significant correlation was observed between the prevalence of palatine cysts, alveolar cysts, or ankyloglossia and maternal or neo-natal factors.
Conclusion: Oral anomalies in newborns are not uncommon, making essential the presence of a dentist, especially a pediatric dentist, in the multidisciplinary team of hospitals and maternal wards.

[New progress in the diagnosis and treatment of natal teeth and neonatal teeth].

There were great individual differences in eruption time of the teeth. Generally speaking, the deciduous teeth begin to erupt at 6 months after birth, but some babies are born with erupted teeth, which are called natal teeth; in addition, teeth erupted within 30 days after the baby is born are called neonatal teeth. Natal teeth and neonatal teeth may cause ulceration, aspiration, and nipple pain or trauma in the mother's breast during the time of breastfeeding. Extraction of the teeth may cause complications such as neonatal osteomyelitis. To avoid the complications caused by these diseases, and to alleviate the suffering of patients and their families, this article will introduce the clinical manifestations, etiology and related complications of natal teeth and neonatal teeth, and then give some treatment methods and nursing methods, especially to help clinical work.

Incidence of Natal Teeth in Sarlahi District of Nepal.

BACKGROUND: The presence of natal or neonatal teeth, which have been associated with environmental factors and hereditary syndromes, can have an impact on the psychosocial growth of children. METHODS: We aimed to estimate the incidence of natal tooth in Sarlahi district of Nepal.Live births from Sarlahi district in Nepal were assessed for natal teeth and other related factors. RESULTS: Among 28,695 live births between 2010 and 2017, we observed 7 cases of natal teeth accounting for an incidence rate of 2.44 per 10,000 (95% CI: 0.98 - 5.03). Out of 7 neonates with natal tooth, 4 were female and 3 were low birth weight (<2500 grams). None were preterm or had any associated cleft lip or palate. CONCLUSIONS: Incidence of natal tooth in Nepal is rare.It is important for health care providers to know about the possibility of occurrence of natal tooth and its management.

Characteristics of Human Natal Stem Cells Cultured in Allogeneic Medium.

Recently, human natal dental pulp stem cells (hNDP-SCs) have been characterized in vitro and it has been shown that they satisfy criteria defining human mesenchymal stromal cells (MSCs), as proposed by the International Society for Cellular Therapy. However, these results were reached in the presence of xenogeneic expansion medium, which has the potential to alter the cells' functional capacity. To determine the validity of the previously reported hNDP-SCs characteristics for human cell therapy, we have cultured hNDP-SCs in allogeneic expansion medium. Two hNDP-SC lineages were isolated from vital natal teeth, donated by a healthy newborn female and cultured in 2% platelet rich plasma (PRP). Analysis of the phenotypic expressions, proliferation rates, viability, telomerase length and in vitro adipogenic, osteogenic and chondrogenic differentiation potentials of two hNDP-SCs lineages (Zn001 and Zn002) were performed. Both lineages displayed similar morphology, proliferation rates, adipogenic, chondrogenic and osteogenic differentiation potential. Telomere shortening by 41.0% and 13.49% occurred from 3rd till 14th passage for lineages Zn001 and Zn002 respectively. Viability of both lineages was higher than 90%. Flow cytometry demonstrated that both lineages were positive to the majority of tested markers, including markers, which were negatively, expressed when hNDP-SCs were cultured previously in xenogeneic medium. Using immune-cytochemistry the cells were shown to express beta III-tubulin, nestin, neurofilaments and Nanog. PRP used as allogeneic medium is suitable for cultivation of hNDP-SCs.