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1.
J Health Care Poor Underserved ; 35(2): 564-582, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38828582

RESUMEN

Background Black individuals with chronic musculoskeletal (MSK) pain tend to experience worse pain and opioid use-related outcomes, including other substance co-use, compared with non-Hispanic White individuals. Co-using cannabis with opioids could instigate a cascade of pain-related vulnerabilities and poor outcomes. Here, we test associations between cannabis/opioid co-use and pain-related outcomes among Black individuals with chronic MSK pain. Methods Black adults with chronic MSK pain who use opioids (N=401; 51.62% female, Mage=35.90, SD=11.03) completed online measures of pain intensity/interference, emotional distress, opioid dependence, and risky use of other substances. Results Compared with opioid use alone, opioid and cannabis co-use was associated with elevated anxiety and depression symptoms, opioid dependence, and risky substance use, but not pain. Conclusions Black individuals with chronic MSK pain who co-use opioids and cannabis warrant targeted interventions that address their needs. Tailored interventions could help address disparities in pain-related outcomes and opioid morbidity and mortality rates.


Asunto(s)
Analgésicos Opioides , Negro o Afroamericano , Dolor Crónico , Trastornos Relacionados con Opioides , Humanos , Femenino , Dolor Crónico/tratamiento farmacológico , Dolor Crónico/etnología , Adulto , Masculino , Analgésicos Opioides/administración & dosificación , Analgésicos Opioides/efectos adversos , Negro o Afroamericano/estadística & datos numéricos , Negro o Afroamericano/psicología , Trastornos Relacionados con Opioides/etnología , Trastornos Relacionados con Opioides/epidemiología , Persona de Mediana Edad , Dolor Musculoesquelético/etnología , Dolor Musculoesquelético/epidemiología , Trastornos Relacionados con Sustancias/epidemiología , Trastornos Relacionados con Sustancias/etnología , Depresión/epidemiología , Depresión/etnología
2.
Rural Remote Health ; 24(2): 8025, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38872100

RESUMEN

INTRODUCTION: Nepali-speaking Bhutanese refugees have been subject to one of the largest resettlement programs in the world and experience higher rates of chronic pain when compared to the general population. The purpose of this study was to explore qualitative conceptualisations of chronic pain among a group of Nepali-speaking Bhutanese adults with a refugee background who relocated to rural and regional Australia. METHODS: Participants included 22 individuals (females n=15) with chronic pain, who took part in structured qualitative focus groups exploring their experiences of chronic pain. Data were analysed using thematic analysis and five main themes were developed. RESULTS: The themes were: (1) pain is persistent and creates suffering, (2) pain is subjective and poorly understood, (3) pain is a biomedical problem that needs to be solved, (4) pain is complex and more than a biomedical problem, and (5) coping with pain is multi-faceted.Some participants viewed pain through a predominantly biomedical lens, and some recognised social and psychological factors as contributors to pain. Overwhelmingly, the participants believed pain is complex and multifaceted, requiring active and passive strategies for management, some of which are culturally informed. CONCLUSION: The experiences of resettled Nepali-speaking Bhutanese refugees living with pain are important to elucidate to improve healthcare inequalities among this marginalised group. This research will inform future assessment guidelines and treatment programs for Nepali-speaking Bhutanese adults living with chronic pain.


Asunto(s)
Dolor Crónico , Grupos Focales , Refugiados , Población Rural , Humanos , Bután/etnología , Femenino , Refugiados/psicología , Refugiados/estadística & datos numéricos , Masculino , Adulto , Dolor Crónico/etnología , Dolor Crónico/psicología , Persona de Mediana Edad , Población Rural/estadística & datos numéricos , Australia , Investigación Cualitativa , Adaptación Psicológica , Nepal/epidemiología , Anciano
3.
Artículo en Inglés | MEDLINE | ID: mdl-38767217

RESUMEN

OBJECTIVES: This study examines how family relationships convey risk or resilience for pain outcomes for aging African Americans, and to replicate and extend analyses across 2 nationally representative studies of aging health. METHODS: African American participants in Midlife in the United States (MIDUS, N = 755) and the Health and Retirement Study (HRS, N = 2,585) self-reported chronic pain status at 2006 waves and then again 10 years later. Logistic regression was used to estimate the odds of pain incidence and persistence explained by family, intimate partner, and parent-child strain and support, as well as average support and average strain across relationships. RESULTS: On average, MIDUS participants were younger (M = 52.35, SD = 12.06; 62.1% female) than HRS (M = 66.65, SD = 10.92; 63.7% female). Family support and average support were linked to decreased odds of pain incidence in MIDUS, but only when tested without accounting for strain, whereas parent-child strain was a risk factor for pain incidence in HRS, as was average strain. Family support protected against pain persistence in MIDUS, whereas average support was linked to reduced odds of pain persisting in HRS. DISCUSSION: Chronic pain outcomes are worse for African Americans for a number of reasons, but parent-child strain may contribute to the risk of new pain developing over time for older adults. Conversely, family support may offer a protective benefit for pain incidence and persistence among aging African Americans. Findings implicate family relationships as a potential target of pain management interventions.


Asunto(s)
Negro o Afroamericano , Dolor Crónico , Relaciones Familiares , Humanos , Femenino , Masculino , Negro o Afroamericano/estadística & datos numéricos , Negro o Afroamericano/psicología , Dolor Crónico/etnología , Dolor Crónico/psicología , Dolor Crónico/epidemiología , Persona de Mediana Edad , Incidencia , Anciano , Estudios Longitudinales , Relaciones Familiares/psicología , Estados Unidos/epidemiología , Apoyo Social , Factores de Riesgo , Envejecimiento/psicología , Envejecimiento/etnología , Adulto
4.
J Pain ; 25(7): 104487, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-38336030

RESUMEN

Understanding patient goals and preferences is critical in the context of complex conditions such as chronic pain. This need may be especially pronounced for Black patients, who experience significant health and healthcare disparities. The primary aim of this study was to describe the treatment goals and preferences of Black veterans with chronic musculoskeletal pain who were enrolled in the intervention arm of a randomized controlled trial testing a coaching intervention. In the coaching sessions, participants (n = 106) identified their most important pain-related treatment goals and preferences. Participants' top treatment goals were to improve physical functioning (61%), increase engagement in valued activities (45%), and reduce pain intensity (37%). Most participants (73%) preferred non-pharmacological treatments (eg, physical therapy, exercise, acupuncture, yoga). The 17% of participants who identified medications as a preferred treatment demonstrated higher levels of depression and anxiety compared to those who did not. Approximately 42% and 21% of participants stated a preference to avoid pharmacological and surgical pain treatments, respectively. Black patients with chronic pain prioritize improving physical functioning and pain intensity in service of increasing their engagement in exercise, work, relationships, and leisure activities. Also, in the current study, patients expressed a clear preference for non-pharmacological pain treatments. Future research should investigate ways to improve communication of goals and preferences with providers and facilitate access to non-pharmacological treatments for Black patients with chronic pain. PERSPECTIVE: This article describes the treatment goals and preferences of Black veterans with chronic pain. Most patients prioritized goals to improve physical functioning, pain severity, and participation in valued activities. Patients primarily preferred non-pharmacological treatments. This emphasizes the need for clear communication with Black patients regarding pain-related goals and non-pharmacological treatment options.


Asunto(s)
Negro o Afroamericano , Dolor Crónico , Dolor Musculoesquelético , Prioridad del Paciente , Veteranos , Humanos , Persona de Mediana Edad , Masculino , Dolor Crónico/terapia , Dolor Crónico/etnología , Femenino , Dolor Musculoesquelético/terapia , Dolor Musculoesquelético/etnología , Negro o Afroamericano/etnología , Anciano , Adulto , Objetivos , Manejo del Dolor/métodos
5.
Pain ; 165(7): 1513-1522, 2024 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-38323608

RESUMEN

ABSTRACT: Chronic low back pain (cLBP) is a global health crisis that disproportionately burdens non-Hispanic Black (NHB) individuals, compared with those who identify as non-Hispanic White (NHW). Despite the growing personal and societal impact of cLBP, its biological underpinnings remain poorly understood. To elucidate the biological factors that underlie the racial disparities in cLBP, this study sought to determine whether inflammatory mediators associated with pain interference (PI), pain at rest (PAR), and movement-evoked pain (MEP) differ as a function of racial identity. Blood samples were collected from 156 individuals with cLBP (n = 98 NHB participants, n = 58 NHW participants). Enzyme-linked immunosorbent assay and multiplex assays were used to quantify concentrations of proinflammatory (fibrinogen, C-reactive protein [CRP], serum amyloid A, tumor necrosis factor α [TNF-α], and interleukin [IL]-1α, IL-1ß, and IL-6) and anti-inflammatory markers (IL-4 and IL-13). Spearman rho correlations were used to assess associations among markers of inflammation and PI, PAR, and MEP using the Brief Pain Inventory-Short Form. Analyses revealed that for NHW patients, CRP, serum amyloid A, and IL-6 were positively associated with cLBP outcomes and IL-4 was inversely associated with PAR and MEP. However, for NHB patients, only IL-1α was positively associated with PAR. Our findings suggest that, while there are associations between inflammation and cLBP outcomes, the biomarkers that underlie the inflammation could very well differ as a function of racialized minority group. However, more research with racially inclusive samples is needed to elucidate the mechanisms that may contribute to racial disparities in cLBP.


Asunto(s)
Dolor Crónico , Dolor de la Región Lumbar , Población Blanca , Humanos , Masculino , Dolor de la Región Lumbar/sangre , Dolor de la Región Lumbar/etnología , Femenino , Persona de Mediana Edad , Adulto , Dolor Crónico/sangre , Dolor Crónico/etnología , Mediadores de Inflamación/sangre , Negro o Afroamericano , Biomarcadores/sangre , Dimensión del Dolor/métodos , Anciano , Inflamación/sangre
6.
Pain ; 165(6): 1372-1379, 2024 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-38189183

RESUMEN

ABSTRACT: The number of people immigrating from one country to another is increasing worldwide. Research has shown that immigration background is associated with chronic pain (CP) and pain disability in adults. However, research in this issue in children and adolescents has yielded inconsistent results. The aims of this study were to examine (1) the association between immigration background, CP, high-impact chronic pain (HICP) in a community sample of children and adolescents; and (2) the extent these associations differed as a function of sex and age. Participants of this cross-sectional study were 1115 school children and adolescents (mean age = 11.67; 56% girls). Participants were asked to provide sociodemographic information and respond to a survey including measures of pain (location, extension, frequency, intensity, and interference). Results showed that having an immigration background was associated with a greater prevalence of CP (OR = 1.91, p <.001) and HICP (OR = 2.55, p <. 01). Furthermore, the association between immigration background and CP was higher in children (OR = 6.92, p <.001) and younger adolescents (OR = 1.66, p <.05) than in older adolescents. Children and adolescents with an immigration background are at higher risk for having CP -especially younger children- and HICP. More resources should be allocated in the prevention of CP and HICP in children and adolescents with an immigration background.


Asunto(s)
Dolor Crónico , Humanos , Masculino , Adolescente , Femenino , Dolor Crónico/epidemiología , Dolor Crónico/etnología , Niño , España/epidemiología , Factores de Riesgo , Estudios Transversales , Emigración e Inmigración/estadística & datos numéricos , Factores de Edad , Prevalencia , Dimensión del Dolor/métodos , Emigrantes e Inmigrantes/estadística & datos numéricos
7.
J Pain ; 25(7): 104480, 2024 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-38246252

RESUMEN

Social stereotypes are more likely to influence decision-making under conditions of high cognitive load (ie, mental workload), such as in medical settings. We examined how patient race, patient socioeconomic status (SES), physician cognitive load, and physician implicit beliefs about race and SES differences in pain tolerance impacted physicians' pain treatment decisions. Physician residents and fellows (N = 120) made treatment decisions for 12 computer-simulated patients with back pain that varied by race (Black/White) and SES (low/high). Half of the physicians were randomized to be interrupted during the decision task to make hypertension medication conversion calculations (high cognitive load group), while the other half completed the task without interruptions (low cognitive load group). Both groups were given equal time to make pain care decisions (2.5 minutes/patient). Results of multilevel ordinal logistic regression analyses indicated that physicians prescribed weaker analgesics to patients with high vs. low SES (odds ratio = .68, 95% confidence interval [.48, .97], P = .03). There was also a patient SES-by-cognitive load interaction (odds ratio = .56, 95% confidence interval [.31, 1.01], P = .05) that is theoretically and potentially practically meaningful but was not statistically significant at P < .05. These findings shed light on physician cognitive load as a clinically-relevant factor in the context of pain care quality and equity. PERSPECTIVE: These findings highlight the clinical relevance of physician cognitive load (eg, mental workload) when providing pain care for diverse patients. This line of work can support the development of interventions to manage physician cognitive load and its impact on pain care, which may ultimately help reduce pain disparities.


Asunto(s)
Dolor Crónico , Clase Social , Humanos , Masculino , Femenino , Dolor Crónico/terapia , Dolor Crónico/etnología , Adulto , Persona de Mediana Edad , Internado y Residencia , Manejo del Dolor , Cognición/fisiología , Médicos , Toma de Decisiones Clínicas , Toma de Decisiones/fisiología
8.
J Immigr Minor Health ; 24(2): 342-350, 2022 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-33725221

RESUMEN

Little is known about the pain experience of the Mexican American (MA) population. We investigated the associations between language use and generation status with chronic pain prevalence, health insurance coverage, and analgesic medication use. We examined 3373 MA respondents from the National Health and Nutrition Examination Survey. We found higher levels of English use and generation status were associated with higher odds of reporting chronic pain. For respondents reporting chronic pain, higher levels of English use and generation status were associated with higher odds of being covered by health insurance, lower odds of having a period of time last year without health insurance, and higher odds of being prescribed any analgesic medication, especially opioid medications. We found language use and generation status play a role in MAs' experience, access, and treatment of chronic pain. Patient-, provider-, and systems-level interventions may be needed to reduce these disparities.


Asunto(s)
Dolor Crónico , Americanos Mexicanos , Humanos , Aculturación , Dolor Crónico/tratamiento farmacológico , Dolor Crónico/etnología , Lenguaje , Encuestas Nutricionales
9.
J Pain ; 23(2): 248-262, 2022 02.
Artículo en Inglés | MEDLINE | ID: mdl-34425249

RESUMEN

Chronic pain is variably associated with brain structure. Phenotyping based on pain severity may address inconsistencies. Sociodemographic groups also differ in the experience of chronic pain severity. Whether differences by chronic pain severity and/or sociodemographic groups are indicated in pain-related areas of the brain is unknown. Relations between 2 measures of chronic pain severity and brain structure via T1-weighted MRI were investigated and sociodemographic group differences explored. The observational study included 142 community-dwelling (68 non-Hispanic Black [NHB] and 74 non-Hispanic White [NHW]) adults with/at risk for knee osteoarthritis. Relationships between chronic pain severity, sociodemographic groups, and a priori selected brain structures (postcentral gyrus, insula, medial orbitofrontal, anterior cingulate, rostral middle frontal gyrus, hippocampus, amygdala, thalamus) were explored. Chronic pain severity associated with cortical thickness. NHB participants reported lower sociodemographic protective factors and greater clinical pain compared to NHWs who reported higher sociodemographic protective factors and lower clinical pain. Greater chronic pain severity was associated with smaller amygdala volumes in the NHB group and larger amygdala volumes in the NHW group. Brain structure by chronic pain stage differed between and within sociodemographic groups. Overall, chronic pain severity and sociodemographic factors are associated with pain-related brain structures. Our findings highlight the importance of further investigating social and environmental contributions in the experience of chronic pain to unravel the complex array of factors contributing to disparities. PERSPECTIVE: The study presents data demonstrating structural brain relationships with clinical pain severity, characteristic pain intensity and chronic pain stage, differ by sociodemographic groups. Findings yield insights into potential sources of previous inconsistent pain-brain relationships and highlights the need for future investigations to address social and environmental factors in chronic pain disparities research.


Asunto(s)
Amígdala del Cerebelo/patología , Corteza Cerebral/patología , Dolor Crónico , Factores Sociodemográficos , Adulto , Negro o Afroamericano/etnología , Anciano , Amígdala del Cerebelo/diagnóstico por imagen , Corteza Cerebral/diagnóstico por imagen , Dolor Crónico/diagnóstico por imagen , Dolor Crónico/etnología , Dolor Crónico/patología , Dolor Crónico/fisiopatología , Humanos , Imagen por Resonancia Magnética , Masculino , Persona de Mediana Edad , Osteoartritis de la Rodilla/diagnóstico por imagen , Osteoartritis de la Rodilla/etnología , Osteoartritis de la Rodilla/patología , Osteoartritis de la Rodilla/fisiopatología , Dimensión del Dolor , Gravedad del Paciente , Población Blanca/etnología
10.
J Pain ; 23(1): 25-44, 2022 01.
Artículo en Inglés | MEDLINE | ID: mdl-34280570

RESUMEN

Disparities in the experience of chronic musculoskeletal pain in the United States stem from a confluence of a broad array of factors. Organized within the National Institute on Aging Health Disparity Research Framework, a literature review was completed to evaluate what is known and what is needed to move chronic musculoskeletal pain research forward specific to disproportionately affected populations. Peer-reviewed studies published in English, on human adults, from 2000 to 2019, and conducted in the United States were extracted from PubMed and Web of Science. Articles were reviewed for key words that focused on underrepresented ethnic/race groups with chronic musculoskeletal pain applying health factor terms identified in the NIAHealth Disparity Research Framework four levels of analysis: 1) environmental, 2) sociocultural, 3) behavioral, and 4) biological. A total of 52 articles met inclusion criteria. There were limited publications specific to underrepresented ethnic/race groups with chronic musculoskeletal pain across all levels with particular research gaps under sociocultural and biological categories. Current limitations in evidence may be supplemented by a foundation of findings specific to the broader topic of "chronic pain" which provides guidance for future investigations. Study designs including a focus on protective factors and multiple levels of analyses would be particularly meritorious. PERSPECTIVE: Chronic musculoskeletal pain unequally burdens underrepresented ethnic/race groups. In order to move research forward and to systematically investigate the complex array of factors contributing toward health disparities, an organized approach is necessary. Applying the NIA Health Disparities Research Framework, an overview of the current state of evidence specific to chronic musculoskeletal pain and underrepresented ethnic/race groups is provided with future directions identified.


Asunto(s)
Investigación Biomédica , Dolor Crónico/etnología , Minorías Étnicas y Raciales , Disparidades en el Estado de Salud , Dolor Musculoesquelético/etnología , Humanos , National Institute on Aging (U.S.) , Estados Unidos/etnología
11.
Respir Med ; 190: 106682, 2021 12.
Artículo en Inglés | MEDLINE | ID: mdl-34788736

RESUMEN

BACKGROUND: Sarcoidosis has been well studied in multiple races and ethnic groups. However, there is a paucity of data that describes sarcoidosis in Hispanics. We aimed to determine the prevalence of Hispanic ethnicity, clinical characteristics and impact of sarcoidosis among Hispanics from a US based national registry. METHODS: We conducted a national registry-based study investigating 3835 respondents to the Sarcoidosis Advanced Registry for Cures questionnaire. This registry is a web-based, self-reported questionnaire that provides data related to demographics, diagnostics, organ involvement, treatment modalities, and the physical and psychosocial impact of sarcoidosis. We compared Hispanic patients to non-Hispanics. We performed multivariate logistic regression analysis adjusting for age, gender, education, income and insurance status and looked at the association between Hispanic ethnicity with depression, chronic pain syndrome, chronic fatigue syndrome, impact on family finances, employment-based disability and job termination. RESULTS: Nine percent of the patients reported a Hispanic ethnicity and the majority of these patients self-identified as white women. The most common organs involved were the lungs (74.9%), central lymph nodes (53.8%), and peripheral lymph nodes (37.1%). Hispanics reported more peripheral nerves and peripheral lymph nodes involvement than non-Hispanics. Hispanics experienced more depression, sleep apnea, and chronic pain syndrome than non-Hispanics. The use of mobility assistive devices was more common among Hispanics, as well as employment-based disability, and disease-related job termination compared to non-Hispanics. The majority of Hispanics reported significantly more pain that interfered with the enjoyment of life than non-Hispanics. On multivariate logistic regression analysis, Hispanic ethnicity was associated with depression (adjusted odds ratio (aOR) = 1.5; 95% CI: 1.01-2.2), chronic pain syndrome (aOR = 1.7; 1.1-2.6), job termination due to sarcoidosis (aOR = 1.7; 1.1-2.7) and higher impact on family finances (aOR = 1.7; 1.1-2.5). CONCLUSION: The clinical presentation of sarcoidosis in Hispanic patients differs from that in non-Hispanic patients living in the United States. These differences should be considered when managing Hispanic patients with sarcoidosis. We encourage more studies that investigate phenotyping among Hispanics with sarcoidosis.


Asunto(s)
Hispánicos o Latinos/estadística & datos numéricos , Sarcoidosis/etnología , Adulto , Dolor Crónico/etnología , Depresión/etnología , Femenino , Humanos , Enfermedades Pulmonares/etnología , Enfermedades Linfáticas/etnología , Masculino , Sistema de Registros , Dispositivos de Autoayuda , Síndromes de la Apnea del Sueño/etnología , Desempleo , Estados Unidos/epidemiología
12.
J Pain ; 22(11): 1452-1466, 2021 11.
Artículo en Inglés | MEDLINE | ID: mdl-34033964

RESUMEN

The current cross-sectional study investigates whether pain catastrophizing mediates the relationship between ethnicity/race and pain, disability and physical function in individuals with knee osteoarthritis. Furthermore, this study examined mediation at 2-year follow-up. Participants included 187 community-dwelling adults with unilateral or bilateral knee pain who screened positive for knee osteoarthritis. Participants completed several self-reported pain-related measures and pain catastrophizing subscale at baseline and 2-year follow-up. Non-Hispanic Black (NHB) adults reported greater pain, disability, and poorer functional performance compared to their non-Hispanic White (NHW) counterparts (Ps < .05). NHB adults also reported greater catastrophizing compared to NHW adults. Mediation analyses revealed that catastrophizing mediated the relationship between ethnicity/race and pain outcome measures. Specifically, NHB individuals reported significantly greater pain and disability, and exhibited lower levels of physical function, compared to NHW individuals, and these differences were mediated by higher levels of catastrophizing among NHB persons. Catastrophizing was a significant predictor of pain and disability 2-years later in both ethnic/race groups. These results suggest that pain catastrophizing is an important variable to consider in efforts to reduce ethnic/race group disparities in chronic pain. The findings are discussed in light of structural/systemic factors that may contribute to greater self-reports of pain catastrophizing among NHB individuals. PERSPECTIVE: The current study examines whether pain catastrophizing mediates the relationship between ethnicity/race and OA-related pain, disability, and functional impairment at baseline and during a 2-year follow-up period in non-Hispanic Black and non-Hispanic White adults with knee pain. These results point to the need for interventions that target pain catastrophizing.


Asunto(s)
Negro o Afroamericano/etnología , Catastrofización/etnología , Dolor Crónico/etnología , Osteoartritis de la Rodilla/etnología , Población Blanca/etnología , Anciano , Estudios Transversales , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Estados Unidos/etnología
13.
J Pain ; 22(11): 1429-1451, 2021 11.
Artículo en Inglés | MEDLINE | ID: mdl-34033965

RESUMEN

Native Americans (NAs) experience higher rates of chronic pain than the general U.S. population, but the risk factors for this pain disparity are unknown. NAs also experience high rates of stressors and cardiovascular and metabolic health disparities (eg, diabetes, cardiovascular disease) consistent with allostatic load (stress-related wear-and-tear on homeostatic systems). Given that allostatic load is associated with chronic pain, then allostatic load may contribute to their pain disparity. Data from 302 healthy, pain-free men and women (153 NAs, 149 non-Hispanic Whites [NHW]) were analyzed using structural equation modeling to determine whether cardiometabolic allostatic load (body mass index, blood pressure, heart rate variability) mediated the relationship between NA ethnicity and experimental measures of pronociceptive processes: temporal summation of pain (TS-pain) and the nociceptive flexion reflex (TS-NFR), conditioned pain modulation of pain (CPM-pain) and NFR (CPM-NFR), and pain tolerance. Results indicated that NAs experienced greater cardiometabolic allostatic load that was related to enhanced TS-NFR and impaired CPM-NFR. Cardiometabolic allostatic load was unrelated to measures of pain perception (CPM-pain, TS-pain, pain sensitivity). This suggests cardiometabolic allostatic load may promote spinal sensitization in healthy NAs, that is not concomitant with pain sensitization, perhaps representing a unique pain risk phenotype in NAs. PERSPECTIVE: Healthy, pain-free Native Americans experienced greater cardiometabolic allostatic load that was associated with a pronociceptive pain phenotype indicative of latent spinal sensitization (ie, spinal sensitization not associated with hyperalgesia). This latent spinal sensitization could represent a pain risk phenotype for this population.


Asunto(s)
Alostasis/fisiología , Indio Americano o Nativo de Alaska/etnología , Factores de Riesgo Cardiometabólico , Sensibilización del Sistema Nervioso Central/fisiología , Dolor Crónico/etnología , Dolor Crónico/fisiopatología , Nocicepción/fisiología , Umbral del Dolor/fisiología , Adulto , Femenino , Humanos , Análisis de Clases Latentes , Masculino , Persona de Mediana Edad , Oklahoma/etnología
14.
N Z Med J ; 134(1533): 11-20, 2021 04 16.
Artículo en Inglés | MEDLINE | ID: mdl-33927420

RESUMEN

AIM: To evaluate outcomes from chronic pain services in New Zealand based on patient ethnicity. METHOD: Clinical and demographic data were obtained from 4,876 patients from the Electronic Persistent Pain Outcomes Collaboration (ePPOC) database, a database of standardised assessments from chronic pain services across New Zealand. Clinical questionnaires included the Brief Pain Inventory (BPI); Depression, Anxiety and Stress Scale - 21 items (DASS-21); Pain Catastrophising Scale (PCS); and the Pain Self-Efficacy Questionnaire (PSEQ). Regression analysis (adjusting for age, body mass index, and baseline values) was used to determine whether patient ethnicity was associated with clinical questionnaire data at treatment end and at 3-6-month follow-up. RESULTS: At treatment end, there were significantly poorer scores for Pacific people compared to Europeans for several of the DASS-21 and PCS subscales, while there were no differences between European and Maori and Asian ethnicities. At follow-up, almost all outcome measures were poorer for Maori compared to European, and several of the DASS-21 and PCS subscales were poorer for Asian and Pacific people compared to Europeans. CONCLUSION: There are ethnic inequalities in the efficacy of treatment for chronic pain services in New Zealand. The cultural safety of the chronic pain clinics should be reviewed regarding both assessment and management procedures.


Asunto(s)
Dolor Crónico/etnología , Dolor Crónico/terapia , Disparidades en Atención de Salud/etnología , Adulto , Pueblo Asiatico , Asistencia Sanitaria Culturalmente Competente , Femenino , Estudios de Seguimiento , Encuestas de Atención de la Salud , Equidad en Salud , Humanos , Masculino , Persona de Mediana Edad , Nativos de Hawái y Otras Islas del Pacífico , Nueva Zelanda , Evaluación de Resultado en la Atención de Salud , Clínicas de Dolor/organización & administración , Población Blanca
15.
J Neurosci Res ; 99(5): 1207-1235, 2021 05.
Artículo en Inglés | MEDLINE | ID: mdl-33606287

RESUMEN

Chronic musculoskeletal (MSK) pain is disabling to individuals and burdensome to society. A relationship between telomere length and resilience was reported in individuals with consideration for chronic pain intensity. While chronic pain associates with brain changes, little is known regarding the neurobiological interface of resilience. In a group of individuals with chronic MSK pain, we examined the relationships between a previously investigated resilience index, clinical pain and functioning measures, and pain-related brain structures, with consideration for sex and ethnicity/race. A cross-sectional analysis of 166 non-Hispanic Black and non-Hispanic White adults, 45-85 years of age with pain ≥ 1 body site (s) over the past 3 months was completed. Measures of clinical pain and functioning, biobehavioral and psychosocial resilience, and structural MRI were completed. Our findings indicate higher levels of resilience associate with lower levels of clinical pain and functional limitations. Significant associations between resilience, ethnicity/race, and/or sex, and pain-related brain gray matter structure were demonstrated in the right amygdaloid complex, bilateral thalamus, and postcentral gyrus. Our findings provide compelling evidence that in order to decipher the neurobiological code of chronic pain and related protective factors, it will be important to improve how chronic pain is phenotyped; to include an equal representation of females in studies including analyses stratifying by sex, and to consider other sociodemographic factors.


Asunto(s)
Encéfalo/diagnóstico por imagen , Dolor Crónico/diagnóstico por imagen , Dolor Crónico/etnología , Dimensión del Dolor/métodos , Resiliencia Psicológica/fisiología , Factores Sociodemográficos , Anciano , Anciano de 80 o más Años , Población Negra/etnología , Población Negra/psicología , Encéfalo/fisiología , Dolor Crónico/psicología , Estudios Transversales , Femenino , Humanos , Masculino , Persona de Mediana Edad , Dimensión del Dolor/psicología , Estudios Prospectivos , Población Blanca/etnología , Población Blanca/psicología
16.
Arch Phys Med Rehabil ; 102(6): 1049-1058, 2021 06.
Artículo en Inglés | MEDLINE | ID: mdl-33556352

RESUMEN

OBJECTIVE: To determine and compare the effect of yoga, physical therapy (PT), and education on depressive and anxious symptoms in patients with chronic low back pain (CLBP). DESIGN: Secondary analysis of a randomized controlled trial. SETTING: Academic safety net hospital and 7 community health centers. PARTICIPANTS: A total of 320 adults with CLBP. INTERVENTION: Yoga classes, PT sessions, or an educational book. OUTCOME MEASURE: Depression and anxiety were measured using the Patient Health Questionnaire and Generalized Anxiety Disorder 7-item Scale, respectively, at baseline, 12, and 52 weeks. We identified baseline and midtreatment (6-wk) factors associated with clinically meaningful improvements in depressive (≥3 points) or anxious (≥2 points) symptoms at 12 weeks. RESULTS: Participants (female=64%; mean age, 46.0±10.7 years) were predominantly non-White (82%), low-income (<$30,000/year, 59%), and had not received a college degree (71%). Most participants had mild or worse depressive (60%) and anxious (50%) symptoms. At 12 weeks, yoga and PT participants experienced modest within-group improvements in depressive symptoms (mean difference [MD]=-1.23 [95% CI, -2.18 to -0.28]; MD=-1.01 [95% CI, -2.05 to -0.03], respectively). Compared with the education group, 12-week differences were not statistically significant, although trends favored yoga (MD=-0.71 [95% CI, -2.22 to 0.81]) and PT (MD= -0.32 [95% CI, -1.82 to 1.18]). At 12 weeks, improvements in anxious symptoms were only found in participants who had mild or moderate anxiety at baseline. Independent of treatment arm, participants who had 30% or greater improvement in pain or function midtreatment were more likely to have a clinically meaningful improvement in depressive symptoms (odds ratio [OR], 1.82 [95% CI, 1.03-3.22]; OR, 1.79 [95% CI, 1.06-3.04], respectively). CONCLUSIONS: In our secondary analysis we found that depression and anxiety, common in this sample of underserved adults with CLBP, may improve modestly with PT and yoga. However, effects were not superior to education. Improvements in pain and function are associated with a decrease in depressive symptoms. More research is needed to optimize the integration of physical and psychological well-being in PT and yoga.


Asunto(s)
Ansiedad/rehabilitación , Dolor Crónico/psicología , Depresión/rehabilitación , Dolor de la Región Lumbar/psicología , Educación del Paciente como Asunto/métodos , Modalidades de Fisioterapia/psicología , Yoga/psicología , Adulto , Ansiedad/etnología , Ansiedad/etiología , Dolor Crónico/etnología , Dolor Crónico/rehabilitación , Depresión/etnología , Depresión/etiología , Femenino , Humanos , Dolor de la Región Lumbar/etnología , Dolor de la Región Lumbar/rehabilitación , Masculino , Persona de Mediana Edad , Cuestionario de Salud del Paciente , Pobreza/psicología , Grupos Raciales/psicología , Resultado del Tratamiento
17.
J Pain ; 22(7): 826-851, 2021 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-33636375

RESUMEN

We provide national surveillance estimates of pain chronicity, severity and impact in adult subpopulations defined by both Hispanic Ancestry and Race. Data are from 144,434 adults who completed validated questionnaires in the 2010-2017 National Health Interview Survey asking about pain status within the last 3 (N = 84,664) or 6 months (N = 59,770). Multivariable logistic regression was used to assess the relationship between pain and ethnicity/race. Compared to White Puerto Rican participants, White participants with Central/South American and Mexican ancestry had reduced odds of reporting Category 3-4 pain and High-Impact Chronic Pain (HICP), while those of Cuban ancestry had reduced odds of only HICP - eg, White participants with Mexican ancestry had 32% lower odds of having Category 3-4 pain and 50% lower odds of having HICP. While no differences were seen between White Puerto Rican and White Non-Hispanic participants for Category 3-4 pain, White Non-Hispanics had 40% lower odds of reporting HICP. Asian Non-Hispanic and Black Non-Hispanic participants had significantly lower odds of reporting Category 3-4 pain and HICP compared to White Puerto Rican participants, eg, Black Non-Hispanic participants had 26% lower odds off having Category 3-4 pain and 42% lower odds of having HICP. Perspective: By examining pain status in discrete demographic groups based on Hispanic Ancestry and Race, this report further documents substantial difference in health status among underserved populations and provides a baseline for continuing surveillance research on pain, with the eventual goal of eliminating disparities in pain assessment and treatment.


Asunto(s)
Negro o Afroamericano/estadística & datos numéricos , Dolor Crónico/etnología , Hispánicos o Latinos/estadística & datos numéricos , Población Blanca/estadística & datos numéricos , Adolescente , Adulto , Anciano , América Central/etnología , Femenino , Encuestas Epidemiológicas , Humanos , Modelos Logísticos , Masculino , México/etnología , Persona de Mediana Edad , Prevalencia , Puerto Rico/etnología , Factores Socioeconómicos , América del Sur/etnología , Estados Unidos/epidemiología , Adulto Joven
18.
Spine (Phila Pa 1976) ; 46(9): E528-E533, 2021 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-33315774

RESUMEN

STUDY DESIGN: Cultural adaptation and psychometric analysis. OBJECTIVE: This study determined the test-retest reliability, acceptability, internal consistency, divergent validity of the Yoruba pain self-efficacy questionnaire (PSEQ-Y). It also examined the ceiling and floor effects and the small detectable change (SDC) of the PSEQ-Y among patients with chronic low back pain (LBP). SUMMARY OF BACKGROUND DATA: There are various indigenous language translations of the PSEQ and none adapted to African language. However, translations of the PSEQ into Nigerian languages are not readily available. METHODS: The validity testing phase of the study involved 131 patients with LBP, while 83 patients with LBP took part in the reliability phase. Following the Beaton recommendation for cultural adaptation of instruments, the PSEQ was adapted into the Yoruba language. The psychometric properties of the PSEQ-Y determined comprised: internal consistency, divergent validity, test-retest reliability, and SDC. RESULTS: The mean age of the participants was 52.96 ±â€Š17.3 years. The PSEQ-Y did not correlate with the Yoruba version of Visual Analogue Scale (VAS-Y) scores (r = -0.05; P = 0.59). The values for the internal consistency and the test-retest reliability of the PSEQ-Y were 0.79 and 0.86, with the 95% confidence interval of the test-retest reliability ranging between 0.82 and 0.90. The standard error of measurement (SEM) and the SDC of the PSEQ-Y were 1.2 and 3.3, respectively. The PSEQ-Y had no floor or ceiling effect, as none of the respondents scored either the minimal or maximal scores. CONCLUSION: This is the first study in Nigeria to culturally adapt PSEQ. The PSEQ-Y showed adequate psychometric properties similar to existing versions. Therefore, the tool can be used to assess pain self-efficacy in clinical and research settings and help to improve the health outcomes of patients chronic LBP.Level of Evidence: 3.


Asunto(s)
Dolor Crónico/diagnóstico , Comparación Transcultural , Dolor de la Región Lumbar/diagnóstico , Dimensión del Dolor/normas , Autoeficacia , Traducciones , Adaptación Fisiológica/fisiología , Adulto , Anciano , Dolor Crónico/etnología , Estudios Transversales , Femenino , Humanos , Dolor de la Región Lumbar/etnología , Masculino , Persona de Mediana Edad , Nigeria/etnología , Dimensión del Dolor/métodos , Psicometría/métodos , Psicometría/normas , Reproducibilidad de los Resultados , Encuestas y Cuestionarios/normas
19.
J Prim Health Care ; 12(3): 225-234, 2020 09.
Artículo en Inglés | MEDLINE | ID: mdl-32988444

RESUMEN

INTRODUCTION Chronic pain affects a large proportion of the adult population and people in pain need to learn how to manage it in order to maintain quality of life. AIM This study aimed to examine how well people with long-term conditions make use of self-management strategies to control their pain, and to identify personal attributes associated with a higher degree of success. METHODS People with chronic pain who participated in the first phase of a longitudinal long-term conditions study in the MidCentral region made up the study sample (N=326, response rate 21%). They completed a questionnaire by mail or online, which included items on pain management, general health, patient activation, experiences with general practice and demographics. RESULTS Pain control strategies were managed fairly well overall. Taking pain medication and avoiding caffeine, alcohol, heavy meals and exercise before bed were managed best, whereas sleep, relaxation breathing and remaining socially active were managed least well. A multiple regression analysis found higher scores on patient activation, self-rated overall pain management at home, mental health and older age (≥75 years) to be associated with better management. DISCUSSION This study identified pain control strategies that are managed well, and less well, outside of a specific intervention. Results highlight topics for discussion in consultations and identify areas where general practice could provide better self-management support, such as sleep and exercise. Better overall pain control strategy management was most strongly associated with patient activation; that is, a combination of knowledge, skills and confidence to manage health and health care that is amenable to intervention. Improving the level of activation in people with long-term conditions may enhance their use of pain control strategies.


Asunto(s)
Dolor Crónico/epidemiología , Dolor Crónico/terapia , Conductas Relacionadas con la Salud , Salud Mental , Manejo del Dolor/métodos , Adulto , Factores de Edad , Anciano , Anciano de 80 o más Años , Dolor Crónico/etnología , Femenino , Medicina General , Conocimientos, Actitudes y Práctica en Salud , Estado de Salud , Humanos , Estudios Longitudinales , Masculino , Persona de Mediana Edad , Participación del Paciente , Atención Primaria de Salud , Calidad de Vida , Sueño , Factores Socioeconómicos
20.
Int J Circumpolar Health ; 79(1): 1787022, 2020 12.
Artículo en Inglés | MEDLINE | ID: mdl-32780007

RESUMEN

In international studies, higher prevalence of persistent pain has been reported in indigenous populations compared to majority populations. The present study aimed to determine the prevalence of persistent pain within a Sami and a non-Sami population in northern Norway, with adjustment for the confounding factors of age, sex, marital status, education, income, mental health, smoking status and ethnic background. Using SAMINOR 2 survey data including Sami and non-Sami populations, we analysed 5,546 responses, from individuals aged 40-79 years, to questions concerning persistent pain (≥ 3 months). In total, 2,426 (43.7%) participants reported persistent pain with differences between Sami women and non-Sami women (44.1% versus 51.1%, respectively), but none between Sami men and non-Sami men (38.7% versus 38.2%, respectively). Elderly Sami women were less likely to report persistent pain than were elderly non-Sami women. In men, no ethnic differences in pain were observed according to age-group. Marital status, education levels, household income, psychological distress, and smoking status did not influence the association between ethnicity and pain. Pain severity and location did not differ between Sami and non-Sami participants. In this study, we found only minor ethnic differences in persistent pain. Similar living conditions and cultural features may explain these findings.


Asunto(s)
Dolor Crónico/etnología , Adulto , Anciano , Regiones Árticas/epidemiología , Estudios Transversales , Etnicidad , Femenino , Humanos , Pueblos Indígenas , Masculino , Persona de Mediana Edad , Noruega/epidemiología , Prevalencia , Índice de Severidad de la Enfermedad , Factores Sexuales , Factores Socioeconómicos
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