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1.
World J Urol ; 42(1): 553, 2024 Sep 30.
Artículo en Inglés | MEDLINE | ID: mdl-39347813

RESUMEN

INTRODUCTION: Urethral strictures and fistulas arising after gender-affirming surgery in transmen require meticulous management strategies. This study evaluates the safety and efficacy of urethral reconstruction and patient satisfaction post-surgery. METHODS: A retrospective analysis examined peri- and postoperative data from transmen undergoing urethral reconstruction for urethral fistula and/or strictures at the distal urethral anastomosis between December 2017 and April 2023. Follow-up involved clinical examinations, uroflowmetry, and voiding cystourethrography. Patient satisfaction and quality of life were assessed using USS PROM and ICIQ-S questionnaires. RESULTS: Among 25 patients, 88% (n = 23) had urethral fistulas, and 48% (n = 12) had urethral strictures. 41% of fistula patients also had strictures, while 75% of stricture patients had concurrent fistulas. Previous surgeries for fistula or stricture repair were noted in 26% of cases. Techniques for stricture included modified flap (50%), buccal oral mucosal grafting (33%), and primary anastomosis (17%). Post-operative urethrogram revealed urethral strictures in 15% (n = 3) and urinary extravasation in an equal number. Postoperative uroflow parameters showed improvement (Qmax 18 ml/s, Qave 7.9 ml, time 37 s, volume 332 ml). Perioperative complications were low (n = 6, 24%), all grade one (Clavien-Dindo). Follow-up revealed that 33% required another surgical intervention. The mean six-item LUTS score was 6.7 (SD 3.9). Mean ICIQ-S overall satisfaction score was 8.6 (SD 1.6) and outcome score was 20 (SD 2.8). DISCUSSION: Our study found a significant recurrence rate of urethral strictures and fistulas post-surgery. Despite this, patient satisfaction remains high and complications are generally low-grade, highlighting the importance of expert surgical intervention.


Asunto(s)
Medición de Resultados Informados por el Paciente , Complicaciones Posoperatorias , Cirugía de Reasignación de Sexo , Uretra , Estrechez Uretral , Fístula Urinaria , Humanos , Estrechez Uretral/cirugía , Estrechez Uretral/etiología , Masculino , Estudios Retrospectivos , Adulto , Fístula Urinaria/cirugía , Fístula Urinaria/etiología , Uretra/cirugía , Cirugía de Reasignación de Sexo/métodos , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/epidemiología , Femenino , Persona de Mediana Edad , Enfermedades Uretrales/cirugía , Enfermedades Uretrales/etiología , Satisfacción del Paciente , Pene/cirugía , Adulto Joven , Procedimientos de Cirugía Plástica/métodos , Procedimientos Quirúrgicos Urológicos Masculinos/métodos , Faloplastia
3.
J Pediatr Urol ; 20(4): 692.e1-692.e6, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-38951046

RESUMEN

BACKGROUND: Urethrocutaneous fistula (UCF) formation is a known complication following hypospadias repair, affecting between 5 and 70% of cases. Moreover, approximately 30% of patients experience refistulization after UCF repair. The use of extracellular matrices, such as AmnioCord, a dehydrated human umbilical cord allograft manufactured by MiMedx®, may mitigate high rates of refistulization. OBJECTIVE: To determine whether the use of AmnioCord during UCF repair is associated with reduced incidence of subsequent UCFs among pediatric patients. DESIGN, SETTING, AND PARTICIPANTS: Electronic medical records were retrospectively reviewed among 60 patients who underwent at least one UCF repair at a pediatric hospital in a large urban setting in the U.S. between January 2012-June 2018. Patients were followed through January 2024. OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS: Adjusted generalized estimating equation regression models were used to assess the association between AmnioCord use and rates of refistulization, while controlling for confounding variables. RESULTS: The number of fistula presentations per patient ranged from one to four; 53.3% had one fistula, 30.0% had two, and 16.6% had three or more. Overall fistula repair success rate was 56.8% but significantly differed by AmnioCord use in adjusted modelling; 69.4% of cases that received AmnioCord were successfully repaired, compared to 47.2% of cases that did not receive AmnioCord. In adjusted models, patients who received AmnioCord had 2.66 times greater odds of surgical success than patients who did not receive AmnioCord (95% CI:1.13-6.24; p = 0.02). CONCLUSIONS: This study demonstrates a positive association between AmnioCord use and successful UCF closure among pediatric patients.


Asunto(s)
Fístula Cutánea , Hipospadias , Complicaciones Posoperatorias , Cordón Umbilical , Enfermedades Uretrales , Fístula Urinaria , Humanos , Masculino , Estudios Retrospectivos , Fístula Urinaria/etiología , Fístula Urinaria/cirugía , Fístula Urinaria/epidemiología , Fístula Cutánea/etiología , Fístula Cutánea/cirugía , Fístula Cutánea/epidemiología , Preescolar , Hipospadias/cirugía , Enfermedades Uretrales/cirugía , Enfermedades Uretrales/etiología , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/etiología , Cordón Umbilical/cirugía , Lactante , Resultado del Tratamiento , Niño , Procedimientos Quirúrgicos Urológicos Masculinos/métodos , Aloinjertos
4.
F1000Res ; 13: 222, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38984015

RESUMEN

Introduction: A urethral diverticulum can be defined as a pocket that forms from the lining of the urethra and protrudes into the surrounding tissue, a condition which causes voiding dysfunction and may result as a rare complication of hypospadias repair surgery. Case report: We report the case of a 2-year-old child who presented to us in 2019 complaining of a thin forceful stream, ballooning of the ventral aspect of the penis while voiding, and post-void dribbling. He has a history of undergoing a tubularised incised plate urethroplasty for distal penile hypospadias at 18-months-old. Ultrasound showed increased post-void residual volume and cystourethroscopy confirmed a urethral diverticulum extending from the subcorona to the base of the penis. The patient underwent partial excision of diverticulum, urethroplasty, and meatoplasty. He was followed-up 3 months later with complete resolution of his symptoms and a normal urinary stream with no urethral ballooning or dribbling. Conclusion: Urethral diverticulum may present as a complication post hypospadias repair. Although it is rare, we believe that it is important for the patient's parents to understand the possibility and know of the signs and symptoms in addition to attending regular outpatient clinic appointments in order to facilitate early management if needed. Furthermore, it is highly important for physicians to assess newborns for hypospadias before carrying out circumcision as it is a contraindication for the procedure.


Asunto(s)
Divertículo , Hipospadias , Enfermedades Uretrales , Humanos , Masculino , Hipospadias/cirugía , Divertículo/etiología , Divertículo/cirugía , Preescolar , Enfermedades Uretrales/etiología , Complicaciones Posoperatorias/etiología , Uretra/cirugía
5.
Urology ; 191: 130-135, 2024 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-38834146

RESUMEN

OBJECTIVE: To present our experience with a novel technique that combines the York-Mason transsphincteric approach with dartos muscle flap interposition to treat rectourethral fistulas. METHODS: We extracted records from our prospectively kept database of 35 procedures conducted for treating rectourethral fistulas during 2002-2023; the York-Mason approach was combined with dartos muscle flap interposition in 5 cases, performed for treating rectourethral fistulas due to radical prostatectomy, all of which were referral cases. RESULTS: All 5 patients were successfully treated and followed up for a median of 70.0 months without recurrence. Before the fistula repair, all had a diverting stoma. In all cases, the first voiding cystourethrogram revealed a healed fistula. The posterior and the scrotal incisions healed uneventfully. All patients reported normal voiding and no urinary incontinence. To date, the stoma has closed in 3 patients, all of whom had intact fecal continence and no postoperative anal stenosis. CONCLUSION: The transsphincteric modified York-Mason approach combined with dartos muscle flap interposition resulted in complete healing of rectourethral fistulas.


Asunto(s)
Prostatectomía , Fístula Rectal , Colgajos Quirúrgicos , Enfermedades Uretrales , Fístula Urinaria , Humanos , Masculino , Fístula Rectal/cirugía , Fístula Rectal/etiología , Prostatectomía/métodos , Prostatectomía/efectos adversos , Fístula Urinaria/cirugía , Fístula Urinaria/etiología , Enfermedades Uretrales/cirugía , Enfermedades Uretrales/etiología , Colgajos Quirúrgicos/trasplante , Persona de Mediana Edad , Anciano , Escroto/cirugía , Procedimientos Quirúrgicos Urológicos Masculinos/métodos , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/cirugía , Estudios Retrospectivos , Resultado del Tratamiento
7.
BMC Urol ; 24(1): 121, 2024 Jun 11.
Artículo en Inglés | MEDLINE | ID: mdl-38862925

RESUMEN

PURPOSE: Various complications following hypospadias surgery present distinct manifestations when examined with ultrasound. Utilizing high-frequency ultrasound, clinicians can promptly identify these complications and initiate appropriate treatment. The aim of this study is to catalogue the ultrasonographic presentations of various postoperative complications following hypospadias surgery, thereby providing a reference for ultrasonographic diagnosis. METHODS: Ultrasonic images of post-hypospadias surgery from October 1, 2015, to June 30, 2023, recorded at the Plastic Surgery Hospital of the Chinese Academy of Medical Sciences, serve as the basis for this investigation. Drawing on patient clinical diagnoses, this study compiles and selects representative ultrasound images of diverse complications. RESULTS: The study encompassed a total of 121 subjects; 26 demonstrated urethral stricture on ultrasonic images, two presented local urethral dilation, six showed intraurethral hair-like structures, 17 revealed intraurethral septum, two exhibited intraurethral fold, one had urethral calculus, one displayed urethral calcification, 12 indicated intraurethral urine accumulation, and two showed urethral diverticulum. CONCLUSION: Ultrasound examination is helpful for postoperative diagnosis following hypospadias, detecting complications such as urethral stricture, urethral hair growth, and urethral diverticulum, which can help doctors choose appropriate clinical treatment strategies.


Asunto(s)
Hipospadias , Complicaciones Posoperatorias , Ultrasonografía , Humanos , Hipospadias/cirugía , Masculino , Complicaciones Posoperatorias/diagnóstico por imagen , Complicaciones Posoperatorias/etiología , Preescolar , Lactante , Niño , Estrechez Uretral/etiología , Estrechez Uretral/diagnóstico por imagen , Adolescente , Enfermedades Uretrales/etiología , Enfermedades Uretrales/diagnóstico por imagen , Estudios Retrospectivos
8.
Croat Med J ; 65(3): 288-292, 2024 Jun 13.
Artículo en Inglés | MEDLINE | ID: mdl-38868974

RESUMEN

We report on a case of a two-year-old male dog, breed chow-chow, who suffered from urethral fistula as a result of ureterolithiasis. The urethral defect was identified intraoperatively with methylene blue. An autologous regenerative approach was combined with surgical closure of the defect, due to the well-known healing issues of the urethral wall in such conditions. A part of abdominal fat tissue was dissected to produce microfragmented adipose tissue containing mesenchymal stem cells, which was combined with platelet-rich plasma. The final product was applied in the area around the urethral defect closure. One month after the procedure, healing was confirmed with positive-contrast cystography. This therapeutic approach yielded success, and the follow-up period of one year was uneventful. The observed positive outcome of this approach in the canine model may be considered as a starting point for investigating the translational potential of the treatment in human medicine.


Asunto(s)
Trasplante de Células Madre Mesenquimatosas , Masculino , Animales , Perros , Tejido Adiposo/citología , Fístula Urinaria/etiología , Fístula Urinaria/terapia , Fístula Urinaria/veterinaria , Fístula Urinaria/cirugía , Enfermedades de los Perros/terapia , Enfermedades de los Perros/cirugía , Enfermedades de los Perros/etiología , Enfermedades Uretrales/etiología , Enfermedades Uretrales/veterinaria , Enfermedades Uretrales/terapia , Enfermedades Uretrales/cirugía , Resultado del Tratamiento , Humanos
9.
BJU Int ; 134(4): 589-595, 2024 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-38817129

RESUMEN

OBJECTIVE: To evaluate the effect of a new strategy of transperineal anastomotic urethroplasty (TAU) with proximal transection in treating pelvic fracture urethral injury (PFUI) associated with urethrorectal fistula (URF). PATIENTS AND METHODS: A retrospective review of all patients treated by TAU with proximal transection and fistula repair for PFUI associated with URF was performed between August 2013 and July 2022. Information on demographics, peri-operative variables, and postoperative follow-up outcomes was collected. Successful surgery was defined as restoration of a uniform urethral calibre using flexible cystoscopy (third postoperative month) without strictures or leakage, with no further interventions required. Functional outcomes, including erectile function (assessed using the five-item International Index of Erectile Function) and urinary continence, were assessed. RESULTS: Forty patients diagnosed with PFUI associated with URF and treated by TAU with proximal transection and rectal fistula repair were enrolled. Six patients (15.0%) had a history of failed urethral reconstruction. The mean stenosis length and fistula diameter were 2.9 cm and 1.2 cm, respectively. All patients underwent faecal diversion before urethroplasty. After a median (range) follow-up of 45 (3-115) months, the final success rate was 90.0% (36/40). Postoperative complications included haematoma in three patients, epididymo-orchitis in three, wound infection in one, wound bleeding in one, delayed wound healing in three, and wound numbness in three. The overall incidence of postoperative erectile dysfunction reached 75.0%, with a median (range) score of 9 (0-19). Normal continence was achieved in 31 patients (77.5%). Occasional incontinence without the need for urinal pads occurred in eight patients, whereas one patient required urinal pads. CONCLUSIONS: Transperineal anastomotic urethroplasty with proximal transection is a precise and effective surgical strategy for treating PFUI associated with URF. This strategy ensures a high success rate and improves surgical efficiency.


Asunto(s)
Fracturas Óseas , Huesos Pélvicos , Fístula Rectal , Uretra , Enfermedades Uretrales , Fístula Urinaria , Humanos , Masculino , Estudios Retrospectivos , Adulto , Fracturas Óseas/complicaciones , Fracturas Óseas/cirugía , Uretra/cirugía , Uretra/lesiones , Fístula Urinaria/cirugía , Fístula Urinaria/etiología , Huesos Pélvicos/lesiones , Huesos Pélvicos/cirugía , Enfermedades Uretrales/cirugía , Enfermedades Uretrales/etiología , Enfermedades Uretrales/complicaciones , Persona de Mediana Edad , Fístula Rectal/cirugía , Fístula Rectal/complicaciones , Anastomosis Quirúrgica , Adulto Joven , Resultado del Tratamiento
10.
Int Urogynecol J ; 35(6): 1327-1329, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38733381

RESUMEN

INTRODUCTION AND HYPOTHESIS: This video illustrates a rare surgical case involving a urethral diverticulum, urethrovaginal fistula, and mesh erosion. METHODS: We present a 58-year-old patient attending a tertiary care center with a suspected urethrovaginal fistula. Her concerns included stress urinary incontinence (SUI), recurrent urinary tract infection, and vaginal pain. The surgical history was notable for the placement of two different mesh slings during the same procedure to treat SUI. Preoperative evaluation and findings are illustrated in detail. The video uses a high-definition surgical camera to emphasize the initial intraoperative evaluation with localization of the fistula and diverticulum. We then demonstrate the approach to the dissection with the goal of ensuring complete resection of the diverticulum, fistula, and mesh, while preserving healthy tissue for subsequent closure. The utilization of unique and specialized tools for each portion of the procedure is also illustrated. A layered vaginal closure, including a Martius flap, is created to prevent recurrence. RESULTS: The surgery was accomplished without complications. CONCLUSIONS: To our knowledge, concomitant findings of a urethral diverticulum, urethrovaginal fistula, and mesh erosion are unique in the literature. We postulate that this triad could have resulted from the mesh burden in this particular patient.


Asunto(s)
Divertículo , Mallas Quirúrgicas , Enfermedades Uretrales , Fístula Urinaria , Fístula Vaginal , Humanos , Femenino , Persona de Mediana Edad , Divertículo/cirugía , Fístula Vaginal/cirugía , Fístula Vaginal/etiología , Enfermedades Uretrales/cirugía , Enfermedades Uretrales/etiología , Mallas Quirúrgicas/efectos adversos , Fístula Urinaria/cirugía , Fístula Urinaria/etiología , Incontinencia Urinaria de Esfuerzo/cirugía , Incontinencia Urinaria de Esfuerzo/etiología , Cabestrillo Suburetral/efectos adversos
11.
PLoS Med ; 21(5): e1004385, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38768094

RESUMEN

BACKGROUND: Syndromic management is widely used to treat symptomatic sexually transmitted infections in settings without aetiologic diagnostics. However, underlying aetiologies and consequent treatment suitability are uncertain without regular assessment. This systematic review estimated the distribution, trends, and determinants of aetiologies for vaginal discharge, urethral discharge, and genital ulcer in sub-Saharan Africa (SSA). METHODS AND FINDINGS: We searched Embase, MEDLINE, Global Health, Web of Science, and grey literature from inception until December 20, 2023, for observational studies reporting aetiologic diagnoses among symptomatic populations in SSA. We adjusted observations for diagnostic test performance, used generalised linear mixed-effects meta-regressions to generate estimates, and critically appraised studies using an adapted Joanna Briggs Institute checklist. Of 4,418 identified records, 206 reports were included from 190 studies in 32 countries conducted between 1969 and 2022. In 2015, estimated primary aetiologies for vaginal discharge were candidiasis (69.4% [95% confidence interval (CI): 44.3% to 86.6%], n = 50), bacterial vaginosis (50.0% [95% CI: 32.3% to 67.8%], n = 39), chlamydia (16.2% [95% CI: 8.6% to 28.5%], n = 50), and trichomoniasis (12.9% [95% CI: 7.7% to 20.7%], n = 80); for urethral discharge were gonorrhoea (77.1% [95% CI: 68.1% to 84.1%], n = 68) and chlamydia (21.9% [95% CI: 15.4% to 30.3%], n = 48); and for genital ulcer were herpes simplex virus type 2 (HSV-2) (48.3% [95% CI: 32.9% to 64.1%], n = 47) and syphilis (9.3% [95% CI: 6.4% to 13.4%], n = 117). Temporal variation was substantial, particularly for genital ulcer where HSV-2 replaced chancroid as the primary cause. Aetiologic distributions for each symptom were largely the same across regions and population strata, despite HIV status and age being significantly associated with several infection diagnoses. Limitations of the review include the absence of studies in 16 of 48 SSA countries, substantial heterogeneity in study observations, and impeded assessment of this variability due to incomplete or inconsistent reporting across studies. CONCLUSIONS: In our study, syndrome aetiologies in SSA aligned with World Health Organization guidelines without strong evidence of geographic or demographic variation, supporting broad guideline applicability. Temporal changes underscore the importance of regular aetiologic re-assessment for effective syndromic management. PROSPERO NUMBER: CRD42022348045.


Asunto(s)
Úlcera , Excreción Vaginal , Humanos , África del Sur del Sahara/epidemiología , Femenino , Excreción Vaginal/epidemiología , Excreción Vaginal/etiología , Úlcera/epidemiología , Enfermedades de Transmisión Sexual/epidemiología , Enfermedades de Transmisión Sexual/diagnóstico , Vaginosis Bacteriana/epidemiología , Vaginosis Bacteriana/diagnóstico , Vaginosis Bacteriana/complicaciones , Infecciones por Chlamydia/epidemiología , Infecciones por Chlamydia/complicaciones , Infecciones por Chlamydia/diagnóstico , Enfermedades Uretrales/epidemiología , Enfermedades Uretrales/etiología , Enfermedades de los Genitales Femeninos/epidemiología
12.
J Pediatr Urol ; 20(4): 675-679, 2024 Aug.
Artículo en Inglés | MEDLINE | ID: mdl-38670858

RESUMEN

INTRODUCTION: The most prevalent complication in hypospadias repair is fistula formation. Adhering to the principle of providing urethroplasty coverage to mitigate fistula occurrence, we implemented a modification by integrating a spongiosum layer between the urethroplasty and the dartos flap. Our hypothesis posited that this approach would result in a reduced fistula formation rate. METHODS: This study is a comparative analysis involving patients under 18 years of age who underwent primary hypospadias repair. The cases were allocated into two groups. In the study group, in addition to performing tubularized incised plate (TIP) repair, a spongiosum layer harvested from both sides of the urethra was used to cover the urethroplasty (modification of the Y-to-I urethroplasty). The control group underwent a standard TIP repair. The primary outcome was to assess urethrocutaneous fistula formation. Secondary outcomes included evaluating the development of meatal stenosis and glans dehiscence, along with assessing cosmetic results by the Hypospadias Objective Penile Evaluation (HOPE) score. RESULTS: Overall, 154 hypospadias cases were included in the study. Eighty-seven patients (56%) were allocated to the study group, and 67 (44%) were allocated to the control group. Urethrocutaneous fistula developed in 3 (3.4%) and 11 (16.4%) patients in the study and control group, respectively (p = 0.006). Glans dehiscence occurred in 2 (2.3%) patients in the study group and 4 (6%) patients in the control group (p = 0.198). Meatal stenosis was observed in 4 (4.6%) patients in the study group and 5 (7.5%) patients in the control (p = 0.452). The mean HOPE score was 59 in both groups (p = 0.36). DISCUSSION: This study details our encounters with the novel modification and compares the results with standard TIP. Our data suggest that adding a layer of spongiosum tissue over the urethroplasty reduces the complication of urethrocutaneous fistula without increasing the occurrence of dehiscence, significant meatal stenosis, or compromising cosmetic outcomes. CONCLUSION: We advocate for implementing the described surgical modification as a viable option for hypospadias repair.


Asunto(s)
Hipospadias , Complicaciones Posoperatorias , Colgajos Quirúrgicos , Fístula Urinaria , Procedimientos Quirúrgicos Urológicos Masculinos , Humanos , Hipospadias/cirugía , Masculino , Procedimientos Quirúrgicos Urológicos Masculinos/métodos , Fístula Urinaria/prevención & control , Fístula Urinaria/etiología , Preescolar , Complicaciones Posoperatorias/prevención & control , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/epidemiología , Niño , Lactante , Uretra/cirugía , Fístula Cutánea/prevención & control , Fístula Cutánea/etiología , Procedimientos de Cirugía Plástica/métodos , Estudios Retrospectivos , Resultado del Tratamiento , Adolescente , Enfermedades Uretrales/prevención & control , Enfermedades Uretrales/etiología , Enfermedades Uretrales/cirugía
13.
Pediatr Surg Int ; 40(1): 111, 2024 Apr 20.
Artículo en Inglés | MEDLINE | ID: mdl-38641738

RESUMEN

BACKGROUND: Long-term urinary outcomes after anorectal malformation (ARM) repair are affected by surgical approach and sacral anomalies. This study aimed to compare laparoscopic-assisted anorectoplasty (LAARP) and posterior sagittal anorectoplasty (PSARP) in terms of urinary complications. METHODS: Between 2001 and 2022, 45 patients were treated with LAARP or PSARP. The rectourethral fistula and inflow angle between the fistula and rectum was confirmed by preoperative colonography. The incidence of urinary complications and treatment were compared between the two groups. RESULTS: Four patients (14%) had remnant fistula and five patients (17%) had neurogenic bladder dysfunction in LAARP group, while three patients (18%) had urethral injury in PSARP group. All patients with remnant fistula were asymptomatic and followed without treatment. The incidence of remnant fistula improved between earlier decade and later decade. In all cases with urethral injury, suture repair was performed and no postoperative leakage was noted. All five patients with neurogenic bladder dysfunction had spine abnormalities that required clean intermittent catheterization (CIC) and two were free from CIC finally. CONCLUSIONS: It is important to check inflow angle preoperatively to prevent remnant fistula. For PSARP, meticulous dissection is required when separating fistula from urethra because they create common wall. The most contributing factor to neurogenic bladder is sacral anomalies. Preoperative evaluation and postoperative urinary drainage are important.


Asunto(s)
Malformaciones Anorrectales , Laparoscopía , Fístula Rectal , Enfermedades Uretrales , Vejiga Urinaria Neurogénica , Fístula Urinaria , Humanos , Lactante , Recto/cirugía , Recto/anomalías , Malformaciones Anorrectales/complicaciones , Malformaciones Anorrectales/cirugía , Malformaciones Anorrectales/epidemiología , Vejiga Urinaria Neurogénica/etiología , Laparoscopía/efectos adversos , Resultado del Tratamiento , Fístula Rectal/cirugía , Fístula Rectal/complicaciones , Fístula Urinaria/etiología , Fístula Urinaria/cirugía , Enfermedades Uretrales/etiología , Enfermedades Uretrales/cirugía , Complicaciones Posoperatorias/etiología , Uretra/cirugía , Estudios Retrospectivos , Canal Anal/anomalías
14.
Urologia ; 91(2): 243-248, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-38497528

RESUMEN

INTRODUCTION: Urogenital fistula is a physically, socially and psychologically devastating condition for the patient. In developed countries, these fistulae are typically related to gynecological surgery, pelvic pathology like malignancy or post radiation therapy. In contrast, classical teaching is that urogenital fistulae in the developing countries like India are usually associated with prolonged labor and obstetric complications. This retrospective study conducted at a tertiary care health Institute shows a paradigm shift in epidemiology, etiology and management of genitourinary fistulae in India in recent times. METHODS: This retrospective study included patients undergoing surgical repair for various genitourinary fistulae at our institute from 2016 to 2022. Epidemiology, etiology, site, size and number of fistulae, clinical presentation, and management records of these patients were recorded and reviewed retrospectively. RESULTS: In our study, the mean age of the patients was 38.4 ± 10.2 years. Vesicovaginal Fistula (VVF) was found to be most common fistula in the study population (87.5%) followed by vesicouterine (7.1%) and urethrovaginal fistula (5.4%). The causes of genitourinary fistula were iatrogenic (73.2%), carcinoma of cervix (16.1%), obstructed prolonged labor (7.1%), and genitourinary tuberculosis (3.57%). Among the 48 vesicovaginal fistulas that underwent surgery, 45.8% were treated using a transvaginal approach, 29.2% were managed through a laparoscopic transabdominal repair, and 25% were addressed using a robotic approach. Recurrence occurred in 7.1% of the operated patients. CONCLUSION: Enhanced healthcare services in the country have contributed to a decrease in the incidence of obstructed labor, subsequently reducing related injuries. Iatrogenic injuries resulting from gynecological surgeries and carcinoma cervix have given rise to more complex fistulas, necessitating the implementation of advanced treatment strategies.


Asunto(s)
Centros de Atención Terciaria , Fístula Vesicovaginal , Adulto , Femenino , Humanos , Persona de Mediana Edad , India/epidemiología , Estudios Retrospectivos , Enfermedades Uretrales/epidemiología , Enfermedades Uretrales/etiología , Enfermedades Uretrales/terapia , Fístula Urinaria/epidemiología , Fístula Urinaria/etiología , Fístula Urinaria/terapia , Fístula Vaginal/epidemiología , Fístula Vaginal/etiología , Fístula Vaginal/terapia , Fístula Vesicovaginal/epidemiología , Fístula Vesicovaginal/etiología
15.
J Pediatr Urol ; 20(3): 437.e1-437.e6, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38369430

RESUMEN

INTRODUCTION: Urethrocutaneous fistula (UCF) is a common complication after hypospadias repair with an incidence of 5-10%. Several techniques are described for its repair: small UCFs are frequently corrected by isolation, excision, and closure with apposition of a protective second layer. In 2008 Malone described the PATIO technique: the fistula tract is turned inside out in the urethral lumen preventing contact with passing urine without direct urethral sutures. OBJECTIVE: Aim of our study is to present our outcomes using a modified version of the PATIO technique, with a more reproducible isolation of the tract and without its fixation at the urethral meatus. STUDY DESIGN: We retrospectively reviewed all cases of UCFs corrected with a modified PATIO technique at our center between 2016 and 2020. Data collected from electronical clinical notes were age at UCF closure, location of UCF, presence of meatal stenosis and clinical outcomes. Data are presented as median and IQR. RESULTS: In the study period we performed 425 urethroplasties for distal and mid penile hypospadias. The incidence of UCFs was 7% (30/425) and 25 patients underwent UCF correction with modified PATIO. Median age at repair was 4.5 years (IQR: 2.5-6.2). At a median follow-up of 3 years (IQR: 2-4) recurrence was observed in 5 cases out of 24 with one patient who was lost at follow-up (20.8%). One case was corrected successfully with re-do modified PATIO technique, while 4 are awaiting repair. One cases was lost at follow-up. UFC-recurrence was homogeneously distributed along the study period. DISCUSSION: Risk factors for UCF recurrence are mostly the type of hypospadias, neo-urethral length, and quality of the urethral plate. Among the many existing techniques, we propose a modified version of Malone's PATIO repair. We believe that the use of four stay-suture to isolate the fistula allows a well-defined dissection of the tract along its surface, compared to the use of a single stay-suture. In our experience, there is no need to keep and fix the traction on the fistula tract to the urethral meatus, probably reflecting the efficacy of the fistula closure during the introflection, which is then maintained without traction. Limitations to our study include the retrospective nature of the review, the small sample size of the cohort and the absence of control groups. CONCLUSIONS: Our results appear consistent with literature regarding the efficacy of PATIO principles in treating UCF. Modified PATIO seem to be particularly reproducible, showing encouraging results.


Asunto(s)
Fístula Cutánea , Hipospadias , Complicaciones Posoperatorias , Centros de Atención Terciaria , Enfermedades Uretrales , Fístula Urinaria , Procedimientos Quirúrgicos Urológicos Masculinos , Humanos , Hipospadias/cirugía , Masculino , Estudios Retrospectivos , Fístula Urinaria/etiología , Fístula Urinaria/cirugía , Fístula Cutánea/etiología , Fístula Cutánea/cirugía , Procedimientos Quirúrgicos Urológicos Masculinos/métodos , Procedimientos Quirúrgicos Urológicos Masculinos/efectos adversos , Preescolar , Enfermedades Uretrales/cirugía , Enfermedades Uretrales/etiología , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/etiología , Niño
16.
J Med Case Rep ; 17(1): 522, 2023 Dec 07.
Artículo en Inglés | MEDLINE | ID: mdl-38057872

RESUMEN

BACKGROUND: Otis urethrotomy can sometimes lead to troublesome bleeding after seemingly uneventful procedures. This case report highlights one such case which went unnoticed initially; the bleeding was erroneously ascribed to the prostate, thereby falsely indicting the "decoy" prostate. CASE PRESENTATION: A 78-year-old Asian gentleman was referred to our hospital with complaint of intractable bleeding after undergoing laser enucleation of prostate at another institute, wherein he further underwent unsuccessful bilateral angioembolization of pudendal arteries. On endoscopy (for hemostasis), we found a spurting vessel in the navicular fossa, which was effectively controlled. CONCLUSIONS: This case report highlights the importance of performing prompt endoscopy in case of uncontrolled bleeding after prostate endoscopic surgery.


Asunto(s)
Uretra , Enfermedades Uretrales , Masculino , Humanos , Anciano , Uretra/cirugía , Enfermedades Uretrales/etiología , Enfermedades Uretrales/terapia , Hemorragia , Endoscopía Gastrointestinal
17.
Urol Int ; 107(10-12): 988-994, 2023.
Artículo en Inglés | MEDLINE | ID: mdl-37903477

RESUMEN

Rectourethral fistula (RUF) is an infrequent but severe complication of the treatment of prostate cancer. Herein, we describe a new surgical approach used successfully in 3 patients that incorporates a partially de-epithelialized mid-perineal scrotal flap (MPSF), used as interposition flap, that can be used in almost every patient with RUF after radiotherapy, regardless of having or not a concomitant posterior urethra or bladder neck stricture or contracture that might require a simultaneous urethroplasty. The interposition flap includes well vascularized subcutaneous fat tissue by distal vascular branches of the internal pudendal vessels that reaches without tension the deep perineum up to the posterior bladder neck. The MPSF is a time efficient procedure that allows excellent access to the bulbar urethra and to the surgical plane between rectum and prostate and it does not require a separate incision for the flap harvesting procedure when required.


Asunto(s)
Fístula Rectal , Enfermedades Uretrales , Fístula Urinaria , Masculino , Humanos , Perineo/cirugía , Estudios de Seguimiento , Colgajos Quirúrgicos , Fístula Rectal/cirugía , Fístula Rectal/etiología , Enfermedades Uretrales/cirugía , Enfermedades Uretrales/etiología , Fístula Urinaria/etiología , Fístula Urinaria/cirugía
18.
Tech Coloproctol ; 27(10): 937-944, 2023 10.
Artículo en Inglés | MEDLINE | ID: mdl-36800073

RESUMEN

BACKGROUND: Gracilis muscle interposition (GMI) has been associated with favorable outcomes in treating complex perianal fistulas. Outcomes of GMI may vary according to the fistula etiology, particularly between rectovaginal fistulas in women and rectourethral fistulas (RUF) in men. The aim of this study was to assess the outcome of GMI to treat RUF acquired after prostate cancer treatment. METHODS: This retrospective cohort study included male patients treated with GMI for RUF acquired after prostate cancer treatment between January 2000 and December 2018 in the Department of Colorectal Surgery, Cleveland Clinic Florida. The primary outcome was the success of GMI, defined as complete healing of RUF without recurrence. Secondary outcomes were length of hospital stay and postoperative complications. RESULTS: This study included 53 male patients with a median age of 68 (range, 46-85) years. Patients developed RUF after treatment of prostate cancer with radiation (52.8%), surgery (34%), or transurethral resection of the prostate (TURP) (13.2%). Median hospital stay was 5 (IQR, 4-7) days. Twenty (37.7%) patients experienced 25 complications, the most common being wound infection and dehiscence. Primary healing after GMI was achieved in 28 (52.8%) patients. Fifteen additional patients experienced successful healing of RUF after additional procedures, for a total success rate of 81.1%. Median time to complete healing was 8 (range, 4-56) weeks. The only significant factor associated with outcome of GMI was wound dehiscence (p = 0.008). CONCLUSIONS: Although the initial success rate of GMI was approximately 53%, it increased to 81% after additional procedures. Complications after GMI were mostly minor, with wound complications being the most common. Perianal wound dehiscence was significantly associated with failure of healing of RUF after GMI.


Asunto(s)
Músculo Grácil , Neoplasias de la Próstata , Fístula Rectal , Resección Transuretral de la Próstata , Enfermedades Uretrales , Fístula Urinaria , Humanos , Masculino , Femenino , Persona de Mediana Edad , Anciano , Anciano de 80 o más Años , Músculo Grácil/trasplante , Resección Transuretral de la Próstata/efectos adversos , Estudios Retrospectivos , Fístula Rectal/etiología , Fístula Rectal/cirugía , Fístula Urinaria/etiología , Fístula Urinaria/cirugía , Enfermedades Uretrales/etiología , Enfermedades Uretrales/cirugía , Complicaciones Posoperatorias/etiología , Complicaciones Posoperatorias/cirugía , Neoplasias de la Próstata/cirugía , Resultado del Tratamiento
20.
Urologie ; 62(3): 295-298, 2023 Mar.
Artículo en Alemán | MEDLINE | ID: mdl-36066612

RESUMEN

When taking into consideration the basic principles of fistula surgery, numerous options are available for the surgical repair of rectourethral fistulas. However, there is no standard regarding which surgical method should be used under which circumstances-due to the heterogeneity of this disease. This case report describes the individual adaptation of a surgical technique that is used for the treatment of vesicovaginal fistulas to treat a rectourethral fistula in a patient who had already undergone an unsuccessful fistula closure attempt. Successful closure of the fistula was achieved on the basis of an established method using tissue interposition.


Asunto(s)
Músculo Grácil , Fístula Rectal , Enfermedades Uretrales , Fístula Urinaria , Masculino , Femenino , Humanos , Próstata , Colgajos Quirúrgicos , Fístula Rectal/etiología , Enfermedades Uretrales/etiología , Fístula Urinaria/diagnóstico por imagen
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