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1.
Environ Health Perspect ; 117(10): 1535-40, 2009 Oct.
Artículo en Inglés | MEDLINE | ID: mdl-20019903

RESUMEN

BACKGROUND AND OBJECTIVES: Between November 2007 and March 2008, 18 children died from a rapidly progressive central nervous system disease of unexplained origin in a community involved in the recycling of used lead-acid batteries (ULAB) in the suburbs of Dakar, Senegal. We investigated the cause of these deaths. METHODS: Because autopsies were not possible, the investigation centered on clinical and laboratory assessments performed on 32 siblings of deceased children and 23 mothers and on 18 children and 8 adults living in the same area, complemented by environmental health investigations. RESULTS: All 81 individuals investigated were poisoned with lead, some of them severely. The blood lead level of the 50 children tested ranged from 39.8 to 613.9 microg/dL with a mean of 129.5 microg/dL. Seventeen children showed severe neurologic features of toxicity. Homes and soil in surrounding areas were heavily contaminated with lead (indoors, up to 14,000 mg/kg; outdoors, up to 302,000 mg/kg) as a result of informal ULAB recycling. CONCLUSIONS: Our investigations revealed a mass lead intoxication that occurred through inhalation and ingestion of soil and dust heavily contaminated with lead as a result of informal and unsafe ULAB recycling. Circumstantial evidence suggested that most or all of the 18 deaths were due to encephalopathy resulting from severe lead intoxication. Findings also suggest that most habitants of the contaminated area, estimated at 950, are also likely to be poisoned. This highlights the severe health risks posed by informal ULAB recycling, in particular in developing countries, and emphasizes the need to strengthen national and international efforts to address this global public health problem.


Asunto(s)
Conservación de los Recursos Energéticos , Fuentes Generadoras de Energía , Exposición a Riesgos Ambientales , Intoxicación del Sistema Nervioso por Plomo en la Infancia/sangre , Plomo/sangre , Adolescente , Adulto , Niño , Preescolar , Femenino , Humanos , Lactante , Plomo/toxicidad , Intoxicación del Sistema Nervioso por Plomo en la Infancia/epidemiología , Intoxicación del Sistema Nervioso por Plomo en la Infancia/mortalidad , Masculino , Persona de Mediana Edad , Senegal , Adulto Joven
2.
ScientificWorldJournal ; 7: 479-92, 2007 Mar 30.
Artículo en Inglés | MEDLINE | ID: mdl-17450310

RESUMEN

One of the first steps in addressing the problem of childhood lead poisoning is to identify the possible sources of exposure in specific communities and target high-risk populations with appropriate interventions. Due to several factors, such as lack of funding and lack of blood lead reporting, little information exists regarding the occurrence of childhood lead poisoning and the prevalence of potential exposure sources in the state of Nevada. Following the recent establishment of a Nevada-based Lead Poisoning Program, we compiled the most current information available on Nevadans, and use this knowledge to suggest future research objectives and outreach activities for the state. Accordingly, we identify the characteristics of the vulnerable Nevada populations, explore possible sources of lead exposure unique to Nevada, and summarize the existing data on childhood lead poisoning. Emerging data indicates that Nevada is an area of rapid population growth, characterized by increasing immigration from Latin America, increasing numbers of children from low-income families with no health insurance. Also, childhood lead poisoning may arise from exposure to non-paint sources of lead. After presenting the Nevada statistics, we propose and recommend a set of research and outreach strategies that best suit the needs of Nevada residents.


Asunto(s)
Exposición a Riesgos Ambientales/estadística & datos numéricos , Vivienda/estadística & datos numéricos , Intoxicación del Sistema Nervioso por Plomo en la Infancia/mortalidad , Intoxicación del Sistema Nervioso por Plomo en la Infancia/prevención & control , Prevención Primaria/estadística & datos numéricos , Prevención Primaria/tendencias , Medición de Riesgo/métodos , Niño , Femenino , Humanos , Incidencia , Masculino , Nevada/epidemiología , Factores de Riesgo
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