RESUMEN
Two dogs presented to the emergency service after accidental ingestion of afloqualone tablets, a muscle relaxant used for back pain in humans. Toxic effects of the drug in these dogs included vomiting, respiratory depression, seizures, ataxia, bradycardia, and hematuria. Treatment consisted of fluid diuresis, furosemide, and propofol. Flumazenil, a gamma-amino butyric acid antagonist, was administered intravenously; however, it was not effective in stopping the seizures in these dogs. Both dogs recovered with supportive treatment. To the authors' knowledge, this is the first documented report of afloqualone intoxication in dogs.
Asunto(s)
Enfermedades de los Perros/inducido químicamente , Quinazolinas/envenenamiento , Animales , Ataxia/inducido químicamente , Ataxia/veterinaria , Bradicardia/inducido químicamente , Bradicardia/veterinaria , Perros , Flumazenil/uso terapéutico , Masculino , Quinazolinas/antagonistas & inhibidores , Insuficiencia Respiratoria/inducido químicamente , Insuficiencia Respiratoria/veterinaria , Convulsiones/inducido químicamente , Convulsiones/veterinaria , Vómitos/inducido químicamente , Vómitos/veterinariaAsunto(s)
Parasimpatolíticos/envenenamiento , Centros de Control de Intoxicaciones/estadística & datos numéricos , Propiofenonas/envenenamiento , Quinazolinas/envenenamiento , Enfermedad Aguda , Factores de Edad , Humanos , Japón/epidemiología , Intoxicación/epidemiología , Intoxicación/etiología , Factores de TiempoRESUMEN
Priapism is a rare but recognized complication of certain antihypertensive agents. An association between the antihypertensive, prazosin, and priapism has been reported in the European literature but not in the American urologic literature.