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1.
Int J Soc Psychiatry ; 69(8): 1845-1855, 2023 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-37497932

RESUMEN

BACKGROUND: Employment is an important social determinant of health and is associated with positive health outcomes. However, individuals who have been diagnosed with borderline personality disorder (BPD) are significantly underrepresented in the workforce. Whilst there is an array of evidence based therapeutic interventions, there remains a gap in knowledge regarding the most effective ways to enhance employment outcomes for people with a diagnosis of BPD. AIM: To explore employment interventions for people with BPD, map the available evidence and identify key concepts and knowledge gaps. METHODS: A scoping review was conducted to identify and map the relevant literature. Findings were summarised using a narrative approach. Consultation was provided by a reference group including peer support workers with lived experience of BPD and mental health clinicians. RESULTS: Seven articles met the inclusion criteria, including non-randomised and case study/series designs and a randomised controlled trial protocol, with participant numbers generally low. All programmes combined a psychotherapeutic component with work related goals; however, there were notable differences in relation to the conceptual/theoretical approach of the psychotherapeutic component and delivery of the work-related components. Barriers and enablers to programme participation and success are explored. CONCLUSIONS: This review provides important insights into the characteristics of vocational rehabilitation interventions for people diagnosed with BPD. The findings will inform the co-production of approaches to support people with BPD to engage in employment.


Asunto(s)
Trastorno de Personalidad Limítrofe , Humanos , Trastorno de Personalidad Limítrofe/diagnóstico , Trastorno de Personalidad Limítrofe/rehabilitación , Empleo , Rehabilitación Vocacional , Proyectos de Investigación , Ensayos Clínicos Controlados Aleatorios como Asunto
2.
Psychopathology ; 53(5-6): 239-253, 2020.
Artículo en Inglés | MEDLINE | ID: mdl-33166987

RESUMEN

Difficulty with boredom was eliminated from the formal diagnostic criteria for borderline personality disorder (BPD) in 1994 based on significantly limited, unpublished data. However, it is apparent in clinical practice that boredom remains relevant to BPD. This review synthesizes empirical research, with consideration of theoretical accounts, to critically examine the relevance of boredom to BPD. We first briefly review issues in defining and measuring boredom and offer an expanded conceptualization for BPD, which includes the notion of boredom reactivity, before turning to boredom's differentiation from and overlap with feelings of emptiness, with which it was paired prior to its removal from the DSM. We then discuss perspectives on boredom's significance in BPD, briefly touching on its relevance in other personality disorders. We propose a Boredom Cascade Model that articulates how boredom and boredom reactivity interact with identity disturbance and chronic emptiness to create escalating patterns of behavioral dysregulation and make recommendations for research and treatment.


Asunto(s)
Trastorno de Personalidad Limítrofe/diagnóstico , Tedio , Trastorno de Personalidad Limítrofe/psicología , Trastorno de Personalidad Limítrofe/rehabilitación , Femenino , Humanos , Masculino
3.
Rev. chil. neuropsicol. (En línea) ; 15(1): 12-17, oct. 2020. graf
Artículo en Español | LILACS | ID: biblio-1353767

RESUMEN

La rehabilitación neuropsicológica es una terapia que busca mejorar la independencia y autonomía en pacientes que presentan dificultades cognitivas. El objetivo de la investigación fue determinar la eficacia de un programa de rehabilitación neuropsicológica en una paciente con diagnóstico de trastorno neurocognitivo leve, tipo ejecutivo, asociado a trastorno límite de la personalidad, mediante el fortalecimiento de la atención y de los procesos ejecutivos implicados en la memoria, bajo los principios de sustitución y restitución. Los instrumentos para establecer línea base y para medir el efecto del tratamiento fueron la escala de trastornos de la memoria y la escala de criterios del trastorno límite de la personalidad (TLP) basados en el DSM-V; estos instrumentos se le aplicaron a la paciente y también a su informador para comparar los datos. Los resultados arrojaron una mejoría estadística en las puntuaciones de la escala de trastornos de la memoria y de la escala de criterios para el TLP-DSM-V; pasando de tener una puntuación en memoria de 36 en línea base a 16 después de la intervención, también pasó de tener 3 criterios para impulsividad a 1 criterio después de la intervención. Finalmente se establece la eficacia de la rehabilitación neuropsicológica en los pacientes con TLP, no solo se evidencia mejoría en los síntomas cognitivos asociados a las dificultades en la memoria, sino que también se muestra disminución en los síntomas psiquiátricos asociados con el control de los impulsos.


Neuropsychological rehabilitation is a therapy that seeks to improve independence and autonomy in patients with cognitive difficulties. The objective of the investigation was to determine the efficacy of a neuropsychological rehabilitation program in a patient diagnosed with a mild neurocognitive disorder, executive type, associated with borderline disorder personality, by strengthening attention and executive processes involved in memory, under the principles of substitution and restitution. The instruments to establish a baseline and to measure the effect of treatment were the memory disorders scale and the DSM-V-based borderline personality disorder (BPD) criteria scale; these instruments were applied to the patient and also to her informant to compare the data. The results showed a statistical improvement in the scores of the memory disorders scale and the criteria scale for the BPD-DSM-V; going from having a memory score of 36 at baseline to 16 after the intervention, it also went from having three criteria for impulsivity to one criterion after the intervention. Finally, the efficacy of neuropsychological rehabilitation in patients with BPD is established, not only is there an improvement in the cognitive symptoms associated with memory difficulties, but also a decrease in the psychiatric symptoms associated with impulse control.


Asunto(s)
Humanos , Femenino , Persona de Mediana Edad , Trastorno de Personalidad Limítrofe/rehabilitación , Disfunción Cognitiva/rehabilitación , Trastorno de Personalidad Limítrofe/fisiopatología , Resultado del Tratamiento , Disfunción Cognitiva/fisiopatología , Conducta Impulsiva/fisiología , Neuropsicología/métodos
4.
Trials ; 21(1): 583, 2020 Jun 26.
Artículo en Inglés | MEDLINE | ID: mdl-32591007

RESUMEN

BACKGROUND: The clinical onset of borderline personality disorder (BPD) usually occurs in young people (aged 12-25 years) and commonly leads to difficulty achieving and maintaining vocational (education and/or employment) engagement. While current psychosocial interventions lead to improvements in psychopathology, they have little effect upon functioning. Individual Placement and Support (IPS) is a client-driven model that assists individuals with severe mental illness to engage with education and/or employment appropriate to their personal goals, and that provides ongoing support to maintain this engagement. The objective of the INdividual Vocational and Educational Support Trial (INVEST) is to evaluate the effectiveness of adding IPS to an evidence-based early intervention programme for BPD, with the aim of improving vocational outcomes. METHODS/DESIGN: INVEST is a single-blind, parallel-groups, randomised controlled trial (RCT). The randomisation is stratified by gender and age and uses random permuted blocks. The interventions are 39 weeks of either IPS, or 'usual vocational services' (UVS). Participants will comprise 108 help-seeking young people (aged 15-25 years) with three or more DSM-5 BPD features and a desire to study or work, recruited from the Helping Young People Early (HYPE) early intervention programme for BPD at Orygen, in Melbourne, Australia. All participants will receive the HYPE intervention. After baseline assessment, staff who are blind to the intervention group allocation will conduct assessments at 13, 26, 39 and 52 weeks. At the 52-week primary endpoint, the primary outcome is the number of days in mainstream education/employment since baseline. Secondary outcomes include the cost-effectiveness of the intervention, quality of life, and BPD severity. DISCUSSION: Current treatments for BPD have little impact on vocational outcomes and enduring functional impairment is prevalent among this patient group. IPS is a targeted functional intervention, which has proven effective in improving vocational outcomes for adults and young people with psychotic disorders. This trial will investigate whether IPS is effective for improving vocational (employment and educational) outcomes among young people with subthreshold or full-syndrome BPD. TRIAL REGISTRATION: Australian New Zealand Clinical Trials Registry, ID: ACTRN12619001220156 . 13 September 2019.


Asunto(s)
Trastorno de Personalidad Limítrofe/rehabilitación , Educación , Empleo , Rehabilitación Vocacional/métodos , Adolescente , Adulto , Australia , Trastorno de Personalidad Limítrofe/diagnóstico , Servicios Comunitarios de Salud Mental , Análisis Costo-Beneficio , Intervención Médica Temprana , Humanos , Evaluación de Resultado en la Atención de Salud , Calidad de Vida , Ensayos Clínicos Controlados Aleatorios como Asunto , Método Simple Ciego , Adulto Joven
5.
Early Interv Psychiatry ; 14(5): 619-624, 2020 10.
Artículo en Inglés | MEDLINE | ID: mdl-32026614

RESUMEN

AIM: Borderline personality disorder and severe emotion dysregulation in adolescence is a major public health concern. Dialectical Behaviour Therapy is a promising treatment for suicidality in adolescents. The aim of this work is to present an adaptation of this intervention to the Spanish national health system, Actions for the Treatment of Adolescent Personality (ATraPA). METHOD: Data consists of a description of the different ATraPA subprogrammes, including interventions for adolescents aged 13 to 17 and their families. Participants were referred to ATraPA from different hospitals within the region of Madrid, Spain. RESULTS: ATraPA has been developed as an intensive outpatient treatment and it comprises different subprogrammes. ATraPA-TAI is an intensive outpatient treatment, including a skills-based group, individual therapy and email therapy. ATraPA-FAL is a psychoeducational intervention for families, including emotion regulation strategies for parents themselves. Finally, the Alternatives Group is offered to adolescents during the hospital admission, with the aim of promoting alternative coping skills. The group of therapists provides a support network to the professionals involved in ATraPA. CONCLUSIONS: ATraPA has been successfully implemented in a Child and Adolescent Psychiatry Service within the Spanish national health system. Future studies should address the efficacy of ATraPA using a controlled design.


Asunto(s)
Síntomas Afectivos/rehabilitación , Trastorno de Personalidad Limítrofe/rehabilitación , Terapia Conductual Dialéctica/métodos , Terapia Conductual Dialéctica/organización & administración , Intervención Médica Temprana/métodos , Intervención Médica Temprana/organización & administración , Terapia Familiar/métodos , Responsabilidad Parental/psicología , Adaptación Psicológica , Adolescente , Síntomas Afectivos/psicología , Trastorno de Personalidad Limítrofe/psicología , Niño , Terapia Combinada , Relaciones Familiares/psicología , Femenino , Humanos , Masculino , Resultado del Tratamiento
6.
J Pers Disord ; 34(3): 289-307, 2020 06.
Artículo en Inglés | MEDLINE | ID: mdl-30179577

RESUMEN

Longitudinal studies provide substantial evidence for a high rate of symptomatic remission in borderline personality disorder (BPD), while social and vocational functioning seems to remain consistently impaired. Less data is available on recovery and the associated objective and personal indicators. We examined 58 patients 12-18 years after their diagnosis of BPD and compared two different recovery criteria: observer-based global assessment of functioning and self-rated satisfaction with life (SWL). Symptomatic remission was observed in 81% of the participants (according to DSM-IV), but only 44% of them achieved a GAF level > 60, and only 49% reported SWL within the range of one standard deviation of the normal population. In line with previous research, our data show that DSM symptom remission alone is an insufficient indicator for recovery from BPD. Replacing the GAF with patient-reported satisfaction with life considers empowerment in BPD and offers an efficient alternative criterion for recovery.


Asunto(s)
Trastorno de Personalidad Limítrofe/psicología , Satisfacción del Paciente/estadística & datos numéricos , Satisfacción Personal , Funcionamiento Psicosocial , Ajuste Social , Adulto , Trastorno de Personalidad Limítrofe/rehabilitación , Manual Diagnóstico y Estadístico de los Trastornos Mentales , Humanos , Estudios Longitudinales , Masculino , Persona de Mediana Edad
7.
PLoS One ; 14(7): e0220233, 2019.
Artículo en Inglés | MEDLINE | ID: mdl-31335909

RESUMEN

BACKGROUND: Borderline personality disorder (BPD) is associated with unemployment and impaired functioning. However, a comprehensive understanding of barriers and facilitators to employment from a multidisciplinary perspective is currently lacking. Therefore, the aim of this qualitative study was to explore barriers and facilitators in gaining and maintaining employment in BPD from the perspectives of patients, mental health practitioners (MHPs) and insurance physicians (IPs). METHODS: Fifteen semi-structured interviews were conducted in patients with BPD and two focus groups were carried out among MHPs (n = 7) and IPs (n = 6) following a thematic content analysis approach. RESULTS: All participants described barriers and facilitators relating to three overall themes: characteristics of BPD, stigma, and support to employment. Barriers to employment mainly related to characteristics of BPD, such as low self-image, difficulty posing personal boundaries, difficulty regulating emotions, and lack of structure. MHPs and IPs additionally mentioned externalization and overestimation of competencies on the part of patients. Enhancing emotion regulation and self-reflection by successful treatment was suggested as a facilitator to enhance employment. Increasing collaboration between mental health and vocational rehabilitation services, and increasing knowledge about BPD, were suggested to increase sustainable employment and decrease stigma. CONCLUSIONS: The present findings revealed that both facilitators and barriers are important in gaining and maintaining employment in BPD in which diminishing symptoms, examining stigma and increasing support to employment are key. As a next step, supported employment strategies that follow patient preferences and integrate employment and mental health services, should be studied in the context of BPD.


Asunto(s)
Trastorno de Personalidad Limítrofe/psicología , Empleo/psicología , Personal de Salud/psicología , Pacientes/psicología , Adulto , Trastorno de Personalidad Limítrofe/epidemiología , Trastorno de Personalidad Limítrofe/rehabilitación , Empleo/estadística & datos numéricos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Asistencia Social en Psiquiatría/estadística & datos numéricos
8.
Australas Psychiatry ; 27(1): 56-59, 2019 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-30226078

RESUMEN

OBJECTIVES:: A lack of compassion for oneself, or harsh self-criticism, is associated with a range of psychiatric disorders including borderline personality disorder (BPD). Personal recovery in the context of a mental illness such as BPD involves building a life that is subjectively meaningful and satisfying. Limited self-compassion or harsh self-criticism may be an impediment to recovery from BPD. The association between self-compassion and recovery and self- criticism and recovery were examined. METHOD:: Nineteen individuals diagnosed with BPD completed the Neff Self-Compassion Scale, the Forms of Self-Criticising/Attacking and Self-Reassuring Scale and the Recovery Assessment Scale at a single time point. RESULTS:: There was a strong positive correlation between self-compassion and recovery ( r = 0.75) and a strong negative correlation ( rho = -0.67) between self- criticism and recovery. CONCLUSIONS:: Although preliminary in nature, these results suggest the importance of fostering self-compassion and working to address self-criticism within clinical interventions supporting recovery from BPD.


Asunto(s)
Trastorno de Personalidad Limítrofe/fisiopatología , Trastorno de Personalidad Limítrofe/rehabilitación , Empatía/fisiología , Evaluación de Resultado en la Atención de Salud , Autoimagen , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven
9.
Early Interv Psychiatry ; 13(4): 961-968, 2019 08.
Artículo en Inglés | MEDLINE | ID: mdl-30019851

RESUMEN

AIM: Most mental disorders have their onset by age 25, disrupting normative vocational engagement. Factors associated with vocational disengagement at first contact with specialist treatment are important for service planning. The aim of this paper was to investigate the association between theoretically important factors and vocational disengagement for youth entering mental health treatment. METHODS: A file audit was used to extract vocational data of 145 young people aged 15 to 25 years entering treatment in 2011 at a public youth mental health service in Melbourne, Australia. Comparisons were made across three specialist programs for: psychosis (n = 50), mood disorders (n = 52) and borderline personality pathology (n = 43). Individual characteristics were entered into univariate and multivariate logistic regressions to investigate their associations with vocational disengagement. RESULTS: Educational disengagement was associated with being older (OR = 4.38, P = 0.004) and not living with parents (OR = 2.87, P = 0.038). Unemployment and being NEET (Not in Education, Employment or Training) were both associated with not having commenced tertiary education (OR = 0.23, P = 0.022; OR = 0.05, P = 0.002; respectively). Being NEET was also associated with being older (OR = 6.18, P = 0.004). Primary diagnostic grouping was not associated with vocational disengagement, once accounting for other factors. CONCLUSIONS: The likelihood of vocational disengagement did not differ across disorder groups, implying that intervention should be "transdiagnostic" and might best target education first, specifically post-secondary qualifications. Other domains or variables not measured in this study are also likely to be important, and this might include young people's support systems and symptom severity. Qualitative studies may be useful for exploring further factors relevant to vocational engagement.


Asunto(s)
Trastorno de Personalidad Limítrofe/rehabilitación , Selección de Profesión , Servicios de Salud Mental , Trastornos del Humor/rehabilitación , Trastornos Psicóticos/rehabilitación , Rehabilitación Vocacional , Adolescente , Adulto , Actitud , Trastorno de Personalidad Limítrofe/diagnóstico , Trastorno de Personalidad Limítrofe/psicología , Estudios Transversales , Escolaridad , Empleo/psicología , Femenino , Humanos , Masculino , Trastornos del Humor/diagnóstico , Trastornos del Humor/psicología , Trastornos Psicóticos/diagnóstico , Trastornos Psicóticos/psicología , Victoria , Adulto Joven
10.
Br J Clin Psychol ; 57(4): 473-490, 2018 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-29659031

RESUMEN

OBJECTIVES: This study was the first to explore how staff that work with people diagnosed with borderline personality disorder (BPD) perceive recovery in this client group. These views are important because of the crucial role that staff play in the care of people with BPD, and the challenges that staff experience with these clients. DESIGN: A Q methodology design was used, containing 58 statements about recovery. METHODS: Twenty-nine mental health staff sorted recovery statements according to perceived importance to recovery in BPD. RESULTS: There were two different viewpoints about recovery in BPD. A medically oriented group viewed coping with symptoms and behaviours specific to BPD as being most important to recovery, whereas participants who were more well-being oriented viewed achieving overall well-being that was universally valued regardless of diagnosis as more important. Both groups reported that engaging in socially valued activities such as work and education was not an important aspect of recovery and that people with BPD could be considered to have recovered despite continued impairments in everyday functioning. CONCLUSIONS: Staff perceptions of recovery in BPD can differ, which poses risks for consistent team working, a particularly important issue in this client group due to the relational difficulties associated with the diagnosis. Multidisciplinary teams working with people diagnosed with BPD therefore need to find a forum to promote a shared understanding of each patient's needs and support plans. We advocate that team formulation is a promising approach to achieve more consistent ways of working within teams. PRACTITIONER POINTS: Findings Multidisciplinary teams working with people with borderline personality disorder should use team formulations to create a shared understanding of individual patient's needs and goals for recovery, so they can deliver a consistent approach to care. Recovery questionnaires should be used to develop an understanding of a patient's individual recovery goals. Limitations Opportunity sampling was utilized in recruitment, and the sample was not representative of the general population of staff working with borderline personality disorder. Although views from a wide range of professions were sampled in this research, the views of psychiatrists were not represented.


Asunto(s)
Actitud del Personal de Salud , Trastorno de Personalidad Limítrofe/rehabilitación , Adulto , Trastorno de Personalidad Limítrofe/psicología , Femenino , Personal de Salud , Humanos , Masculino , Percepción , Psicoterapia/métodos , Q-Sort , Encuestas y Cuestionarios
11.
Psychiatry Res ; 262: 459-464, 2018 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-28927866

RESUMEN

'Metacognitive training for borderline personality disorder' (B-MCT) represents a complementary group intervention. It aims at raising awareness for cognitive biases that may play an important role in the development and maintenance of borderline symptomatology. For the present study, we evaluated the effectiveness of this new approach against a control condition. Seventy-four inpatients with borderline personality disorder (BPD) were randomly assigned to metacognitive training for BPD or progressive muscle relaxation training as an add-on intervention to treatment as usual. Severity of symptomatology was assessed at baseline, four weeks after beginning and six months after completion of the intervention. The per-protocol and intention-to-treat analyses revealed that patients in the metacognitive training group showed significantly greater reductions on the primary outcome (Borderline Symptom List-23) after six months. Progressive muscle relaxation was superior in alleviating depressive symptoms (secondary outcome: Beck Depression Inventory) at the long-term follow-up. Findings provide preliminary evidence that metacognitive training for BPD yields surplus effects to standard treatment.


Asunto(s)
Trastorno de Personalidad Limítrofe/terapia , Terapia Cognitivo-Conductual/métodos , Metacognición , Adulto , Entrenamiento Autogénico/métodos , Trastorno de Personalidad Limítrofe/rehabilitación , Femenino , Humanos , Masculino , Resultado del Tratamiento , Adulto Joven
12.
Neuropsychol Rehabil ; 28(3): 416-428, 2018 Apr.
Artículo en Inglés | MEDLINE | ID: mdl-26872501

RESUMEN

Several studies have demonstrated that borderline personality disorder (BPD) is associated with neuropsychological deficits and there is evidence that the neurocognitive profile of patients with BPD may be related to the outcome of this disorder. The aim of this study was to investigate the feasibility and the effectiveness of a cognitive remediation intervention in patients with BPD. Thirty patients with a DSM-IV-TR diagnosis of BPD were assessed on clinical, neuropsychological and functional outcome measures at baseline and after 16 weeks of a computer-assisted cognitive remediation (CACR) intervention or treatment as usual (TAU). Patients who received CACR showed a greater improvement in working memory and psychosocial functioning measures than patients treated with TAU. Symptom severity was not significantly affected by CACR treatment. The findings of this pilot study suggest the feasibility and potential effectiveness on specific cognitive domains, but modest clinical usefulness of a computerised modality of cognitive remediation in the treatment of BPD.


Asunto(s)
Trastorno de Personalidad Limítrofe/etiología , Trastornos del Conocimiento/etiología , Trastornos del Conocimiento/rehabilitación , Remediación Cognitiva/métodos , Adolescente , Adulto , Anciano , Trastorno de Personalidad Limítrofe/psicología , Trastorno de Personalidad Limítrofe/rehabilitación , Femenino , Humanos , Masculino , Persona de Mediana Edad , Pruebas Neuropsicológicas , Escalas de Valoración Psiquiátrica , Factores de Tiempo , Adulto Joven
13.
Personal Ment Health ; 12(1): 38-48, 2018 02.
Artículo en Inglés | MEDLINE | ID: mdl-29024577

RESUMEN

Social-environmental factors have been found to be an integral part in the recovery process for individuals with psychiatric disabilities. There are few studies that have obtained patient perspectives of how their social and treatment environments help facilitate or impede the recovery process. The following study examined the self-reported interpersonal barriers to recovery among a sample of individuals (N = 31) with borderline personality disorder who were receiving dialectical behaviour therapy. The goal of study was to identify self-reported problematic behaviour that interferes with recovery goals and identify types of family, friend and/or provider behaviours that increased the likelihood of patients engaging in these problematic behaviours. A content analysis yielded three themes of problematic behaviour, and how these behaviours were reinforced by others, including (1) avoidance behaviours, (2) encouragement of negative coping and (3) communication of low behavioural expectations. Implications for the impact of these patterns of reinforcement within behavioural health settings are discussed. Copyright © 2017 John Wiley & Sons, Ltd.


Asunto(s)
Adaptación Psicológica , Terapia Conductista/métodos , Trastorno de Personalidad Limítrofe/rehabilitación , Relaciones Interpersonales , Investigación Cualitativa , Centros Médicos Académicos , Adulto , Trastorno de Personalidad Limítrofe/psicología , Femenino , Humanos , Masculino , Servicio Ambulatorio en Hospital
14.
Eur Arch Psychiatry Clin Neurosci ; 267(1): 51-62, 2017 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-27091455

RESUMEN

Neural underpinnings of emotion dysregulation in borderline personality disorder (BPD) are characterized by limbic hyperactivity and disturbed prefrontal activity. It is unknown whether neural correlates of emotion regulation change after a psychotherapy which has the goal to improve emotion dysregulation in BPD, such as dialectical behavioral therapy (DBT). We investigated distraction as a main emotion regulation strategy before and after DBT in female patients with BPD. Thirty-one BPD patients were instructed to either passively view or memorize letters before being confronted with negative or neutral pictures in a distraction task during functional magnetic resonance imaging. This paradigm was applied before and after a 12-week residential DBT-based treatment program. We compared the DBT group to 15 BPD control patients, who continued their usual, non-DBT-based treatment or did not have any treatment, and 22 healthy participants. Behaviorally, BPD groups and healthy participants did not differ significantly with respect to alterations over time. On the neural level, BPD patients who received DBT-based treatment showed an activity decrease in the right inferior parietal lobe/supramarginal gyrus during distraction from negative rather than neutral stimuli when compared to both control groups. This decrease was correlated with improvement in self-reported borderline symptom severity. DBT responders exhibited decreased right perigenual anterior cingulate activity when viewing negative (rather than neutral) pictures. In conclusion, our findings reveal changes in neural activity associated with distraction during emotion processing after DBT in patients with BPD. These changes point to lower emotional susceptibility during distraction after BPD symptom improvement.


Asunto(s)
Terapia Conductista/métodos , Trastorno de Personalidad Limítrofe/diagnóstico por imagen , Trastorno de Personalidad Limítrofe/rehabilitación , Mapeo Encefálico , Encéfalo/patología , Adulto , Encéfalo/diagnóstico por imagen , Femenino , Humanos , Procesamiento de Imagen Asistido por Computador , Imagen por Resonancia Magnética , Masculino , Oxígeno/sangre , Escalas de Valoración Psiquiátrica , Psicometría , Tiempo de Reacción/fisiología , Estadística como Asunto , Factores de Tiempo , Adulto Joven
15.
Sci Rep ; 6: 27617, 2016 06 08.
Artículo en Inglés | MEDLINE | ID: mdl-27272094

RESUMEN

Recovery is a personal process of growth that involves hope, self-identity, meaning in life and responsibility. Determinants of meaning have not been explored among populations of patients with persistent psychiatric conditions. However, an evidence-based approach aiming at assessing such determinants should provide some insight into the psychotherapeutic aspects of recovery. We tested a model hypothesizing that some symptoms and social parameters of patients are related to values, and secondarily to meaning in life, and in turn that meaning is associated with various parameters, such as depressiveness and self-esteem. We assessed 176 patients with schizophrenia, anorexia, borderline personality disorder and bipolar disorder. Overall, our hypotheses proved correct: firstly, characteristics such as depression, hopelessness, self-esteem and the number of relationships influenced values; secondly, the presence and an enactment of values were associated with meaning, and thirdly, meaning was associated with some symptoms and social characteristics. This model was confirmed in the four psychiatric populations under study. These results support the relevance of addressing values and meaning in the recovery-oriented care of patients with persistent psychiatric disorders, in addition to other psychosocial interventions which are more systematically considered in this area.


Asunto(s)
Anorexia/psicología , Trastorno Bipolar/psicología , Esquizofrenia/rehabilitación , Psicología del Esquizofrénico , Adulto , Anorexia/rehabilitación , Trastorno Bipolar/rehabilitación , Trastorno de Personalidad Limítrofe/psicología , Trastorno de Personalidad Limítrofe/rehabilitación , Femenino , Humanos , Masculino , Autoimagen
16.
J Behav Ther Exp Psychiatry ; 52: 147-156, 2016 09.
Artículo en Inglés | MEDLINE | ID: mdl-27132175

RESUMEN

BACKGROUND AND OBJECTIVES: Dialectical behaviour therapy (DBT) trains participants to use behavioural skills for managing their emotions. The study aimed to evaluate whether skills use is associated with positive treatment outcomes independently of treatment processes that are common across different therapeutic models. METHOD: Use of the DBT skills and three common treatment processes (therapeutic alliance, treatment credibility and self-efficacy) were assessed every 2 months for a year in 70 individuals with borderline personality disorder receiving DBT. Mixed-multilevel modelling was used to determine the association of these factors with frequency of self-harm and with treatment dropout. RESULTS: Participants who used the skills less often at any timepoint were more likely to drop out of DBT in the subsequent two months, independently of their self-efficacy, therapeutic alliance or perceived treatment credibility. More frequent use of the DBT skills and higher self-efficacy were each independently associated with less frequent concurrent self-harm. Treatment credibility and the alliance were not independently associated with self-harm or treatment dropout. LIMITATIONS: The skills use measure could not be applied to a control group who did not receive DBT. The sample size was insufficient for structural equation modelling. CONCLUSION: Practising the DBT skills and building an increased sense of self-efficacy may be important and partially independent treatment processes in dialectical behaviour therapy. However, the direction of the association between these variables and self-harm requires further evaluation.


Asunto(s)
Terapia Conductista/métodos , Trastorno de Personalidad Limítrofe/fisiopatología , Trastorno de Personalidad Limítrofe/rehabilitación , Desempeño Psicomotor/fisiología , Adulto , Trastorno de Personalidad Limítrofe/diagnóstico , Estudios de Cohortes , Femenino , Humanos , Masculino , Evaluación de Resultado en la Atención de Salud , Autoinforme , Conducta Autodestructiva/etiología , Adulto Joven
17.
Med Tr Prom Ekol ; (2): 1-6, 2016.
Artículo en Ruso | MEDLINE | ID: mdl-27164743

RESUMEN

The article covers treatment results of 417 patients (186 males and 231 females) aged 18 to 71 years, with borderline mental disorders. Findings are that using specified complementary methods, more when treatment complex is applied, causes better psycho-emotional state in patients with borderline mental disorders, that is supported by results of medical diagnostic tests including psychometry tests (abridged minnesota multiphasic personality inventory, Beck depression inventory, Spielberger-Hanin, test "feeling, activity, mood").


Asunto(s)
Trastorno de Personalidad Limítrofe/tratamiento farmacológico , Trastorno de Personalidad Limítrofe/rehabilitación , Homeopatía/métodos , Reflejoterapia/métodos , Adolescente , Adulto , Anciano , Femenino , Humanos , Masculino , Persona de Mediana Edad , Adulto Joven
18.
Soc Cogn Affect Neurosci ; 11(6): 952-60, 2016 06.
Artículo en Inglés | MEDLINE | ID: mdl-26833918

RESUMEN

With the use of real-time functional magnetic resonance imaging neurofeedback (NF), amygdala activitiy can be visualized in real time. In this study, continuous amygdala NF was provided to patients with borderline personality disorder (BPD) with the instruction to down-regulate. During four sessions of NF training, patients viewed aversive pictures and received feedback from a thermometer display, which showed the amygdala blood oxygenation level-dependent signal. Conditions of regulation and viewing without regulation were presented. Each session started with a resting-state scan and was followed by a transfer run without NF. Amygdala regulation, task-related and resting-state functional brain connectivity were analyzed. Self-ratings of dissociation and difficulty in emotion regulation were collected. BPD patients down-regulated right amygdala activation but there were no improvements over time. Task-related amygdala-ventromedial prefrontal cortex connectivity was altered across the four sessions, with an increased connectivity when regulating vs viewing pictures. Resting-state amygdala-lateral prefrontal cortex connectivity was altered and dissociation, as well as scores for 'lack of emotional awareness', decreased with training. Results demonstrated that amygdala NF may improve healthy brain connectivity, as well as emotion regulation. A randomized-controlled trial is needed to investigate whether amygdala NF is instrumental for improving neural regulation and emotion regulation in BPD patients.


Asunto(s)
Amígdala del Cerebelo/fisiopatología , Trastorno de Personalidad Limítrofe/fisiopatología , Interfaces Cerebro-Computador , Imagen por Resonancia Magnética/métodos , Red Nerviosa/fisiopatología , Neurorretroalimentación/fisiología , Corteza Prefrontal/fisiopatología , Adulto , Trastorno de Personalidad Limítrofe/rehabilitación , Humanos , Neurorretroalimentación/métodos
19.
Behav Res Ther ; 74: 60-71, 2015 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-26432172

RESUMEN

Knowing what predicts discontinuation or success of psychotherapies for Borderline Personality Disorder (BPD) is important to improve treatments. Many variables have been reported in the literature, but replication is needed and investigating what therapy process underlies the findings is necessary to understand why variables predict outcome. Using data of an RCT comparing Schema Therapy and Transference Focused Psychotherapy as treatments for BPD, variables derived from the literature were tested as predictors of discontinuation and treatment success. Participants were 86 adult outpatients (80 women, mean age 30.5 years) with a primary diagnosis of BPD who had on average received 3 previous treatment modalities. First, single predictors were tested with logistic regression, controlling for treatment type (and medication use in case of treatment success). Next, with multivariate backward logistic regression essential predictors were detected. Baseline hostility and childhood physical abuse predicted treatment discontinuation. Baseline subjective burden of dissociation predicted a smaller chance of recovery. A second study demonstrated that in-session dissociation, assessed from session audiotapes, mediated the observed effects of baseline dissociation on recovery, indicating that dissociation during sessions interferes with treatment effectiveness. The results suggest that specifically addressing high hostility, childhood abuse, and in-session dissociation might reduce dropout and lack of effectiveness of treatment.


Asunto(s)
Trastorno de Personalidad Limítrofe/terapia , Pacientes Desistentes del Tratamiento/psicología , Psicoterapia/métodos , Adulto , Trastorno de Personalidad Limítrofe/rehabilitación , Femenino , Humanos , Masculino , Pacientes Ambulatorios , Pronóstico , Escalas de Valoración Psiquiátrica , Resultado del Tratamiento
20.
BMC Psychiatry ; 15: 255, 2015 Oct 21.
Artículo en Inglés | MEDLINE | ID: mdl-26487284

RESUMEN

BACKGROUND: Follow-up studies revealed that subjects with borderline personality disorder (BPD) present high rates of clinical remission, although psychosocial functioning often remains impaired. The aim of this study is to evaluate the efficacy of a cognitive rehabilitation intervention versus a psychoeducational program on psychosocial functioning in subjects with BPD. METHODS: A multicenter, randomized, and positive-controlled clinical trial was conducted. Seventy outpatients with BPD were randomized to cognitive rehabilitation or psychoeducational group interventions. Participants were evaluated after completion of the intervention period (16 weeks) and after the follow-up period (6 months). Psychosocial functioning, clinical and neuropsychological outcomes were evaluated. RESULTS: No main effects of group or group x time were observed on functionality but a significant effect of time was found. Post-hoc analyses showed that only cognitive rehabilitation increased psychosocial functioning significantly at endpoint. Psychoeducation showed a significant enhancement of depressive symptoms. CONCLUSIONS: Cognitive rehabilitation and psychoeducational interventions appeared to show good efficacy in improving disabilities in daily life in subjects with BPD. These interventions are easily implemented in mental health settings and have the advantage of improving general functioning and clinical symptoms. TRIAL REGISTRATION: Clinicaltrials.gov: NCT02033044. Registered 9 January 2014.


Asunto(s)
Trastorno de Personalidad Limítrofe/rehabilitación , Terapia Cognitivo-Conductual/métodos , Adulto , Atención Ambulatoria , Trastorno de Personalidad Limítrofe/psicología , Depresión/rehabilitación , Función Ejecutiva/fisiología , Femenino , Estudios de Seguimiento , Humanos , Relaciones Interpersonales , Masculino , Memoria/fisiología , Educación del Paciente como Asunto/métodos , Resultado del Tratamiento
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