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1.
Top Companion Anim Med ; 39: 100403, 2020 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-32482282

RESUMEN

Gastric dilation-volvulus (GDV) syndrome in dogs is associated with complex metabolic, acid-base, and electrolyte abnormalities. The aim of this study was to evaluate previously analyzed factors (lactate and BE) in combination with other acid-base parameters (pH, pCO2, bicarbonate, base excess [BE], anion gap [AG], and strong ion difference) and electrolyte concentrations and to evaluate their association with the incidence of gastric necrosis and outcome in dogs with GDV. A retrospective study in 75 dogs with gastric dilation-volvulus syndrome, University veterinary teaching hospital. Medical records were reviewed including signalment, history, initial plasma lactate, acid-base parameters, and electrolyte concentrations, surgical findings and outcome. The overall mortality was 18.7%. In dogs with gastric necrosis, higher initial plasma lactate (median 5.84 vs. 3.36 mmol/L) and AG (20.7 vs. 16.55 mmol/L) and lower pH (7.29 vs. 7.36), bicarbonate (18.7 vs. 22.9 mmol/L), and BE concentration (-8.1 vs. -1.85 mmol/L) were found compared to dogs without gastric necrosis. Anorganic phosphorus was the only electrolyte investigated for which a significant difference was noted between dogs with and without gastric necrosis (1.93 vs. 1.39 mmol/L). The initial plasma lactate concentration (3.36 mmol/L vs. 9.68 mmol/L) and AG (16.8 vs. 20.95 mmol/L) were lower in survivors than nonsurvivors. Survivors had higher pH (7.35 vs. 7.27), bicarbonate concentrations (22.9 vs. 17.35 mmol/L), and BE (-1.9 vs. -9.55 mmol/L) compared to nonsurvivors. Anorganic phosphorus was ultimately the only electrolyte with a significant difference between survivors and nonsurvivors (1.4 vs. 1.84 mmol/L). A multivariate logistic regression model of combination lactate, pH, bicarbonate, BE, AG, and anorganic phosphorus identified pH ≤7.331 and bicarbonate as factors independently associated with gastric necrosis. Similarly, pH ˃7.331, bicarbonate and anorganic phosphorus were independently associated with outcome. Higher initial plasma lactate, AG and anorganic phosphorus levels, and lower pH, BE and bicarbonate concentrations were found in GDV dogs with gastric necrosis. Similarly, initially higher plasma lactate, AG and anorganic phosphorus concentrations, and lower pH, BE and bicarbonate were found in GDV dogs who required euthanasia or who died after surgery. Of these parameters, pH and bicarbonate were strongly and independently associated with gastric necrosis, and pH, bicarbonate and phosphorus were independently associated with outcome.


Asunto(s)
Enfermedades de los Perros/mortalidad , Dilatación Gástrica/veterinaria , Vólvulo Gástrico/veterinaria , Animales , República Checa , Enfermedades de los Perros/sangre , Enfermedades de los Perros/patología , Perros , Electrólitos/sangre , Femenino , Dilatación Gástrica/mortalidad , Concentración de Iones de Hidrógeno , Ácido Láctico/sangre , Masculino , Necrosis , Registros/veterinaria , Estudios Retrospectivos , Estómago/patología , Vólvulo Gástrico/mortalidad , Análisis de Supervivencia , Síndrome
2.
J Vet Emerg Crit Care (San Antonio) ; 30(2): 232-238, 2020 Mar.
Artículo en Inglés | MEDLINE | ID: mdl-32077192

RESUMEN

INTRODUCTION: The primary study objective was to characterize the pattern of in-hospital mortality in dogs with gastric dilatation and volvulus (GDV), with a focus on preoperative nonsurvival. MATERIALS AND METHODS: A retrospective review of medical records from a 10-year period was undertaken at a university teaching hospital. Data collected included signalment, physical examination parameters at hospital presentation, blood lactate concentration, and outcome. RESULTS: A total of 498 dogs were included. Overall, 319 (64.1%) survived to discharge and 179 (35.9%) were nonsurvivors. Of the nonsurvivors, 149 (31.3% of all dogs) were euthanized and 30 (6%) died. Of those dogs euthanized, the majority (n = 116) were euthanized at the time of hospital presentation prior to surgery (ie, without intent to treat). When dogs that were euthanized prior to surgery were excluded, 83.5% of dogs survived to discharge. Median group age was higher in those euthanized than in the group of dogs that survived to discharge. CONCLUSIONS: Preoperative euthanasia and hence nonsurvival without intent to treat accounted for the majority of GDV mortality in this study. Given the high rate of nonsurvival without intent to treat it is likely that efforts focused at disease prevention will ultimately affect a much greater improvement in overall disease mortality than those focused on improving treatment.


Asunto(s)
Enfermedades de los Perros/mortalidad , Dilatación Gástrica/veterinaria , Vólvulo Intestinal/veterinaria , Vólvulo Gástrico/veterinaria , Animales , Enfermedades de los Perros/sangre , Enfermedades de los Perros/patología , Perros , Femenino , Dilatación Gástrica/mortalidad , Vólvulo Intestinal/mortalidad , Ácido Láctico/sangre , Masculino , Estudios Retrospectivos , Vólvulo Gástrico/mortalidad
3.
Dig Dis Sci ; 63(11): 3091-3096, 2018 11.
Artículo en Inglés | MEDLINE | ID: mdl-30027515

RESUMEN

BACKGROUND AND AIMS: Gastric volvulus (GV) is a life-threatening condition that warrants prompt diagnosis and treatment. GV is a radiologic diagnosis. The role of preoperative upper gastrointestinal endoscopy (UGIE) for individuals with radiologically confirmed GV is poorly defined. Our objective was to assess the diagnostic yield of UGIE in the preoperative evaluation of patients presenting with radiologically confirmed GV. METHODS: Retrospective review of all adult patients undergoing surgery for GV between July 1996 and August 2016 has been carried out. We performed analyses evaluating diagnostic yield of preoperative UGIE and compared outcomes in patients who did and did not undergo preoperative UGIE. Outcomes were diagnostic yield of preoperative UGIE, length of hospital stay, postoperative complications, and mortality at 30 days and 1 year. RESULTS: In the preoperative UGIE group, the diagnostic yield was 34.6% (27/78). The most common endoscopic findings were erosive esophagitis (13/27) and clean based gastric or duodenal ulcers (5/27). There were no cases of esophago-gastric malignancy. Three patients had ulcers with stigmata of recent bleeding, and three patients had features suggestive of gastric ischemia. Endoscopic findings did not influence surgical management. There was no statistically significant difference in mortality between patients who did and did not undergo preoperative UGIE, both at 30 days (0 vs. 2.5%) and 1 year (3.8 vs. 7.5%). CONCLUSION: Among patients with radiologically confirmed GV, preoperative UGIE rarely demonstrates clinically significant findings and can potentially delay definitive surgical intervention.


Asunto(s)
Gastroscopía/estadística & datos numéricos , Vólvulo Gástrico/diagnóstico , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Humanos , Masculino , Persona de Mediana Edad , Minnesota/epidemiología , Radiografía , Estudios Retrospectivos , Vólvulo Gástrico/complicaciones , Vólvulo Gástrico/mortalidad , Adulto Joven
4.
J Small Anim Pract ; 58(11): 629-638, 2017 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-28833166

RESUMEN

OBJECTIVE: To report prevalence, risk factors and clinical outcomes for presumptive gastric dilation-volvulus diagnosed among an emergency-care population of UK dogs. METHODS: The study used a cross-sectional design using emergency-care veterinary clinical records from the VetCompass Programme spanning September 1, 2012 to February 28, 2014 and risk factor analysis using multivariable logistic regression modelling. RESULTS: The study population comprised 77,088 dogs attending 50 Vets Now clinics. Overall, 492 dogs had presumptive gastric dilation-volvulus diagnoses, giving a prevalence of 0·64% (95% Confidence interval: 0·58 to 0·70%). Compared with cross-bred dogs, breeds with the highest odds ratios for the diagnosis of presumptive gastric dilation-volvulus were the great Dane (odds ratio: 114·3, 95% Confidence interval 55·1 to 237·1, P<0·001), akita (odds ratio: 84·4, 95% Confidence interval 33·6 to 211·9, P<0·001) and dogue de Bordeaux (odds ratio: 82·9, 95% Confidence interval 39·0 to 176·3, P<0·001). Odds increased as dogs aged up to 12 years and neutered male dogs had 1·3 (95% Confidence interval 1·0 to 1·8, P=0·041) times the odds compared with entire females. Of the cases that were presented alive, 49·7% survived to discharge overall, but 79·3% of surgical cases survived to discharge. CLINICAL SIGNIFICANCE: Approximately 80% of surgically managed cases survived to discharge. Certain large breeds were highly predisposed.


Asunto(s)
Enfermedades de los Perros/epidemiología , Dilatación Gástrica/veterinaria , Vólvulo Gástrico/veterinaria , Animales , Cruzamiento , Estudios Transversales , Enfermedades de los Perros/mortalidad , Enfermedades de los Perros/cirugía , Perros , Femenino , Dilatación Gástrica/epidemiología , Dilatación Gástrica/mortalidad , Dilatación Gástrica/cirugía , Masculino , Prevalencia , Factores de Riesgo , Vólvulo Gástrico/epidemiología , Vólvulo Gástrico/mortalidad , Vólvulo Gástrico/cirugía , Reino Unido/epidemiología
5.
J Vet Emerg Crit Care (San Antonio) ; 21(1): 36-44, 2011 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-21288292

RESUMEN

OBJECTIVE: To test whether an initial plasma lactate ≥ 6.0 mmol/L is associated with the presence of macroscopic gastric wall necrosis and overall survival in dogs presenting with gastric dilatation-volvulus (GDV). Additionally, if no association was identified we sought to identify a different predictive initial plasma lactate concentration and to examine whether serial plasma lactate concentrations provide better prediction of survival. DESIGN: Retrospective study over a 5-year period (2003-2007). SETTING: Urban private referral small animal teaching hospital. ANIMALS: Eighty-four client-owned dogs with a diagnosis of GDV and plasma lactate measurements. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: There was no statistically significant relationship found between survival and the presence of macroscopic gastric wall necrosis with the initial plasma lactate ≥ 6 mmol/L. There was a significant relationship between the initial plasma lactate >2.9 mmol/L for predicting necrosis and <4.1 mmol/L for predicting survival to discharge. Forty dogs that had an increased initial plasma lactate (>2.5 mmol/L) also had a subsequent plasma lactate measured within 12 hours of presentation, with 37/40 dogs surviving and 70% of these surviving dogs having the subsequent lactate decrease by ≥ 50% within 12 hours. The 3/40 that died failed to decrease their plasma lactate by ≥ 50% from the initial blood lactate. CONCLUSION: The results of this study indicate that an initial presenting plasma lactate concentration ≥ 6.0 mmol/L is not predictive of macroscopic gastric wall necrosis or survival in dogs presenting with GDV. A decrease in plasma lactate concentrations ≥ 50% within 12 hours may be a good indicator for survival. Limitations to the study include its retrospective nature, the small number of patients, and the number of dogs that were euthanized rather than allowed to progress to a natural outcome.


Asunto(s)
Enfermedades de los Perros/sangre , Enfermedades de los Perros/mortalidad , Dilatación Gástrica/veterinaria , Ácido Láctico/sangre , Vólvulo Gástrico/veterinaria , Animales , Perros , Femenino , Dilatación Gástrica/sangre , Dilatación Gástrica/mortalidad , Masculino , Necrosis/sangre , Necrosis/mortalidad , Necrosis/veterinaria , Estudios Retrospectivos , Vólvulo Gástrico/sangre , Vólvulo Gástrico/mortalidad , Análisis de Supervivencia
6.
J Small Anim Pract ; 51(7): 376-81, 2010 Jul.
Artículo en Inglés | MEDLINE | ID: mdl-20626784

RESUMEN

OBJECTIVES: To estimate breed-specific risk of death due to, and prevalence of, gastric dilatation-volvulus (GDV) in UK pedigree dogs. METHODS: Data were available on the reported cause of and age at death and occurrence of and age at diagnosis of disease from the 2004 purebred dog health survey. A total of 15,881 dogs of 165 breeds had died in the previous 10 years; GDV was the cause of death in 65 breeds. There were 36,006 live dogs of 169 breeds of which 48 breeds had experienced > or =1 episodes of GDV. Prevalence ratios were used to estimate breed-specific GDV mortality and morbidity risks. RESULTS: Gastric dilatation-volvulus was the cause of death for 389 dogs, representing 2.5% (95% CI: 2.2-2.7) of all deaths reported and the median age at death was 7.92 years. There were 253 episodes in 238 live dogs. The median age at first diagnosis was five years. Breeds at greatest risk of GDV mortality were the bloodhound, Grand Bleu de Gascogne, German longhaired pointer and Neapolitan mastiff. Breeds at greatest risk of GDV morbidity were the Grand Bleu de Gascogne, bloodhound, otterhound, Irish setter and Weimaraner. CLINICAL SIGNIFICANCE: These results suggest that 16 breeds, mainly large/giant, are at increased risk of morbidity/mortality due to GDV.


Asunto(s)
Tamaño Corporal/fisiología , Enfermedades de los Perros/mortalidad , Dilatación Gástrica/veterinaria , Linaje , Vólvulo Gástrico/veterinaria , Factores de Edad , Animales , Perros , Femenino , Dilatación Gástrica/mortalidad , Masculino , Prevalencia , Factores de Riesgo , Vólvulo Gástrico/mortalidad , Reino Unido/epidemiología
7.
J Am Anim Hosp Assoc ; 46(2): 97-102, 2010.
Artículo en Inglés | MEDLINE | ID: mdl-20194364

RESUMEN

Gastric dilatation-volvulus (GDV) is a life-threatening condition in dogs that has been associated with high mortality rates in previous studies. Factors were evaluated in this study for their influence on overall and postoperative mortality in 306 confirmed cases of GDV between 2000 and 2004. The overall mortality rate was 10%, and the postoperative mortality rate was 6.1%. The factor that was associated with a significant increase in overall mortality was the presence of preoperative cardiac arrhythmias. Factors that were associated with a significant increase in postoperative mortality were postoperative cardiac arrhythmias, splenectomy, or splenectomy with partial gastric resection. The factor that was associated with a significant decrease in the overall mortality rate was time from presentation to surgery. This study documents that certain factors continue to affect the overall and postoperative mortality rates associated with GDV, but these mortality rates have decreased compared to previously reported rates.


Asunto(s)
Enfermedades de los Perros/mortalidad , Enfermedades de los Perros/cirugía , Dilatación Gástrica/veterinaria , Complicaciones Posoperatorias/veterinaria , Vólvulo Gástrico/veterinaria , Animales , Perros , Femenino , Estudios de Seguimiento , Dilatación Gástrica/mortalidad , Dilatación Gástrica/cirugía , Modelos Logísticos , Masculino , Complicaciones Posoperatorias/mortalidad , Estudios Retrospectivos , Factores de Riesgo , Vólvulo Gástrico/mortalidad , Vólvulo Gástrico/cirugía , Tasa de Supervivencia , Resultado del Tratamiento
8.
Zentralbl Chir ; 133(1): 76-8, 2008 Feb.
Artículo en Alemán | MEDLINE | ID: mdl-18278707

RESUMEN

BACKGROUND: Hepatic portal venous gas, which may occur in conjunction with severe intra-abdominal infections, is associated with a high mortality rate and is considered as an alarm signal. HISTORY: CT diagnostics revealed hepatic portal venous gas in a 65-year-old patient with advanced perforated sigmoid diverticulitis. This phenomenon was also observed in a 75-year-old patient in association with an upside-down stomach incarceration. Both patients underwent emergency surgery and survived this life-threatening disease. CONCLUSION: Since hepatic portal gas is usually caused by severe intra-abdominal diseases with a high mortality rate, this warning sign should, at the latest, result in urgent laparotomy, if the indication has not already been established for other reasons.


Asunto(s)
Absceso Abdominal/diagnóstico por imagen , Diverticulitis del Colon/diagnóstico por imagen , Embolia Aérea/diagnóstico por imagen , Perforación Intestinal/diagnóstico por imagen , Absceso Hepático/diagnóstico por imagen , Vena Porta/diagnóstico por imagen , Enfermedades del Sigmoide/diagnóstico por imagen , Vólvulo Gástrico/diagnóstico por imagen , Infecciones Estreptocócicas/diagnóstico por imagen , Streptococcus , Tomografía Computarizada Espiral , Absceso Abdominal/mortalidad , Absceso Abdominal/cirugía , Anciano , Diverticulitis del Colon/mortalidad , Diverticulitis del Colon/cirugía , Gastrectomía , Humanos , Perforación Intestinal/mortalidad , Perforación Intestinal/cirugía , Absceso Hepático/mortalidad , Absceso Hepático/cirugía , Masculino , Complicaciones Posoperatorias/diagnóstico por imagen , Complicaciones Posoperatorias/mortalidad , Complicaciones Posoperatorias/cirugía , Reoperación , Enfermedades del Sigmoide/mortalidad , Enfermedades del Sigmoide/cirugía , Vólvulo Gástrico/mortalidad , Vólvulo Gástrico/cirugía , Infecciones Estreptocócicas/mortalidad , Infecciones Estreptocócicas/cirugía , Tasa de Supervivencia
10.
J Am Vet Med Assoc ; 230(9): 1334-9, 2007 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-17472559

RESUMEN

OBJECTIVE: To determine clinical features, outcome, risk factors for death, and efficacy of IV administration of lidocaine as a prophylactic treatment for ischemic reperfusion injury in gastric dilatation and volvulus (GDV) in dogs. DESIGN: Retrospective case series. ANIMALS: 112 dogs with GDV. PROCEDURES: Data pertaining to breed; time lag to admission; clinical, clinicopathologic, and surgical findings; lidocaine treatment; and postoperative complications were assessed for association with outcome. RESULTS: German Shepherd Dogs (28.6%) and Great Danes (17%) were significantly over-represented. Risk factors for death included time lag (> or = 5 hours vs < 5 hours) from onset of clinical signs to admission (46.0% vs 11.3%), rectal temperature (< or = 38 degrees C vs > 38 degrees C [< 100.4 degrees F vs > 100.4 degrees F]) at admission (40.0% vs 14.9%), presence or absence of ARF (67.0% vs 23.3%), presence or absence of suspected gastric wall necrosis (59.3% vs 16.0%), and untreated gastric wall necrosis, compared with treated gastric wall necrosis (100% vs 47.6%). Overall mortality rate was 26.8%; no significant differences were detected in mortality rate or postoperative complications between dogs that received lidocaine IV prior to surgical intervention (52.0%) and dogs that did not (48.0%). Mean +/- SD hospitalization time was longer in the lidocaine treatment group (3.5 +/- 1.9 days vs 2.5 +/- 1.4 days). CONCLUSIONS AND CLINICAL RELEVANCE: Presence of the identified risk factors should warrant aggressive treatment. Lidocaine treatment was not associated with mortality rate or postoperative complications, but was associated with prolonged hospitalization time.


Asunto(s)
Enfermedades de los Perros/tratamiento farmacológico , Dilatación Gástrica/veterinaria , Lidocaína/efectos adversos , Lidocaína/uso terapéutico , Vólvulo Gástrico/veterinaria , Animales , Cruzamiento , Enfermedades de los Perros/mortalidad , Enfermedades de los Perros/cirugía , Perros , Femenino , Dilatación Gástrica/tratamiento farmacológico , Dilatación Gástrica/mortalidad , Dilatación Gástrica/cirugía , Predisposición Genética a la Enfermedad , Masculino , Complicaciones Posoperatorias/epidemiología , Complicaciones Posoperatorias/veterinaria , Pronóstico , Estudios Prospectivos , Daño por Reperfusión/prevención & control , Daño por Reperfusión/veterinaria , Factores de Riesgo , Vólvulo Gástrico/tratamiento farmacológico , Vólvulo Gástrico/mortalidad , Vólvulo Gástrico/cirugía , Tasa de Supervivencia , Resultado del Tratamiento
11.
J Am Vet Med Assoc ; 229(12): 1934-9, 2006 Dec 15.
Artículo en Inglés | MEDLINE | ID: mdl-17173533

RESUMEN

OBJECTIVE: To evaluate risk factors associated with death and development of perioperative complications in dogs undergoing surgery for treatment of gastric dilatation-volvulus (GDV). DESIGN: Retrospective case series. ANIMALS: 166 dogs. PROCEDURES: Records of dogs with confirmed GDV that underwent surgery were reviewed. Logistic regression was performed to identify factors associated with development of complications (ie, hypotension, arrhythmias, gastric necrosis necessitating gastrectomy, disseminated intravascular coagulation, peritonitis, sepsis, postoperative dilatation, postoperative vomiting, and incisional problems) and with short-term outcome (ie, died vs survived to the time of suture removal). RESULTS: Short-term mortality rate was 16.2% (27/166). Risk factors significantly associated with death prior to suture removal were clinical signs for > 6 hours prior to examination, combined splenectomy and partial gastrectomy, hypotension at any time during hospitalization, peritonitis, sepsis, and disseminated intravascular coagulation. Partial gastrectomy was not a significant risk factor for death but was for peritonitis, disseminated intravascular coagulation, sepsis, and arrhythmias. Age, gastrectomy, and disseminated intravascular coagulation were risk factors for development of hypotension. Use of a synthetic colloid or hypertonic saline solution was associated with a significantly decreased risk of hypotension. CONCLUSIONS AND CLINICAL RELEVANCE: Results suggest that the prognosis for dogs undergoing surgery because of GDV is good but that certain factors are associated with an increased risk that dogs will develop perioperative complications or die.


Asunto(s)
Enfermedades de los Perros/cirugía , Dilatación Gástrica/veterinaria , Complicaciones Posoperatorias/veterinaria , Vólvulo Gástrico/veterinaria , Animales , Enfermedades de los Perros/mortalidad , Perros , Femenino , Dilatación Gástrica/mortalidad , Dilatación Gástrica/cirugía , Modelos Logísticos , Masculino , Atención Perioperativa , Pronóstico , Estudios Retrospectivos , Factores de Riesgo , Vólvulo Gástrico/mortalidad , Vólvulo Gástrico/cirugía , Tasa de Supervivencia , Resultado del Tratamiento
12.
Prev Vet Med ; 60(4): 319-29, 2003 Sep 12.
Artículo en Inglés | MEDLINE | ID: mdl-12941556

RESUMEN

The lifetime probability of death from gastric dilation-volvulus (GDV) for five dog breeds was estimated based on published breed-specific longevity and GDV incidence. These breeds were Great Dane, Irish Setter, Rottweiler, Standard Poodle and Weimaraner. Lifetime risk (95% CI) of GDV in these breeds ranged from 3.9% (0-11.2%) for Rottweiler to 36.7% (25.2-44.6%) for Great Dane. A decision-tree analysis for prophylactic gastropexy--using lifetime probability of death from GDV and expected cost savings for veterinary services as outcome measures--was undertaken to determine the preferred course of action in several dog breeds. Prophylactic gastropexy was the preferred choice of action for all breeds examined, with the reduction in mortality (versus no gastropexy) ranging from 2.2-fold (Rottweiler) to 29.6-fold (Great Dane). Assuming a prophylactic gastropexy costs US$ 400, the procedure was cost-effective when the lifetime risk of GDV was > or = 34%. The maximum and minimum estimated breakeven costs for the gastopexy procedure ranged from US$ 20 (Rottweiler) to US$ 435 (Great Dane). The cost-effectiveness of prophylactic gastropexy was most sensitive to the cost of treating GDV (US$ 1500). Prophylactic gastropexy raises ethical issues that need to be considered by veterinarians and dog breeders.


Asunto(s)
Enfermedades de los Perros/mortalidad , Dilatación Gástrica/veterinaria , Vólvulo Gástrico/veterinaria , Animales , Cruzamiento , Análisis Costo-Beneficio , Árboles de Decisión , Enfermedades de los Perros/economía , Enfermedades de los Perros/etiología , Enfermedades de los Perros/cirugía , Perros , Procedimientos Quirúrgicos Electivos/economía , Procedimientos Quirúrgicos Electivos/veterinaria , Dilatación Gástrica/economía , Dilatación Gástrica/etiología , Dilatación Gástrica/mortalidad , Dilatación Gástrica/cirugía , Factores de Riesgo , Vólvulo Gástrico/economía , Vólvulo Gástrico/etiología , Vólvulo Gástrico/mortalidad , Vólvulo Gástrico/cirugía , Estados Unidos/epidemiología
13.
J Am Vet Med Assoc ; 215(1): 49-52, 1999 Jul 01.
Artículo en Inglés | MEDLINE | ID: mdl-10397065

RESUMEN

OBJECTIVE: To determine relationships between plasma lactate concentration and gastric necrosis and between plasma lactate concentration and outcome for dogs with gastric dilatation-volvulus. DESIGN: Retrospective study. ANIMALS: 102 dogs. PROCEDURE: Information on signalment, history, plasma lactate concentration, medical and surgical treatment, cost of hospitalization, and outcome was retrieved from medical records. RESULTS: 69 of 70 (99%) dogs with plasma lactate concentration < 6.0 mmol/L survived, compared with 18 of 31 (58%) dogs with plasma lactate concentration > 6.0 mmol/L (1 dog euthanatized for economic reasons was not included). Gastric necrosis was identified in 38 (37%) dogs. Median plasma lactate concentration in dogs with gastric necrosis (6.6 mmol/L) was significantly higher than concentration in dogs without gastric necrosis (3.3 mmol/L). Specificity and sensitivity of using plasma lactate concentration (with a cutoff of 6.0 mmol/L) to predict which dogs had gastric necrosis were 88 and 61%, respectively. Sixty-two of 63 (98%) dogs without gastric necrosis survived, compared with 25 of 38 (66%) dogs with gastric necrosis. CONCLUSIONS AND CLINICAL RELEVANCE: Preoperative plasma lactate concentration was a good predictor of gastric necrosis and outcome for dogs with GDV. Preoperative measurement of plasma lactate concentration may assist in determining prognosis of dogs with GDV.


Asunto(s)
Enfermedades de los Perros/patología , Dilatación Gástrica/veterinaria , Ácido Láctico/sangre , Vólvulo Gástrico/veterinaria , Estómago/patología , Animales , Enfermedades de los Perros/mortalidad , Enfermedades de los Perros/cirugía , Perros , Femenino , Dilatación Gástrica/mortalidad , Dilatación Gástrica/patología , Masculino , Necrosis , Valor Predictivo de las Pruebas , Cuidados Preoperatorios/veterinaria , Curva ROC , Estudios Retrospectivos , Vólvulo Gástrico/mortalidad , Vólvulo Gástrico/patología , Tasa de Supervivencia
14.
J Am Anim Hosp Assoc ; 34(3): 253-9, 1998.
Artículo en Inglés | MEDLINE | ID: mdl-9590454

RESUMEN

Dogs (n = 136) with gastric dilatation-volvulus (GDV) syndrome were followed over time to measure recurrence and mortality rates and to identify prognostic factors. Thirty-three (24.3%) died or were euthanized during the first seven days. Of 85 cases that were followed for up to three years, nine (10.6%) cases each had a recurrence of GDV and seven (8.2%) cases died or were euthanized. The median survival times for cases that had gastropexies and those that did not were 547 and 188 days, respectively. Depressed or comatose cases on admission were three and 36 times, respectively, more likely to die than alert cases, while cases with gastric necrosis were 11 times more likely to die.


Asunto(s)
Enfermedades de los Perros/mortalidad , Dilatación Gástrica/veterinaria , Vólvulo Gástrico/veterinaria , Enfermedad Aguda , Animales , Estudios de Casos y Controles , Intervalos de Confianza , Enfermedades de los Perros/cirugía , Perros , Femenino , Estudios de Seguimiento , Dilatación Gástrica/mortalidad , Dilatación Gástrica/cirugía , Masculino , Oportunidad Relativa , Pronóstico , Estudios Prospectivos , Recurrencia , Factores de Riesgo , Vólvulo Gástrico/mortalidad , Vólvulo Gástrico/cirugía , Análisis de Supervivencia , Síndrome
15.
J Am Vet Med Assoc ; 208(11): 1855-8, 1996 Jun 01.
Artículo en Inglés | MEDLINE | ID: mdl-8675474

RESUMEN

OBJECTIVE: To evaluate factors associated with perioperative mortality in dogs with gastric dilatation-volvulus and to determine the influence of treatment differences between university and private specialty practices on outcome. DESIGN: Retrospective analysis of medical records. ANIMALS: 137 dogs with gastric dilatation-volvulus. PROCEDURE: Signalment; frequency of preoperative and postoperative treatments and complications; intraoperative findings; surgical technique; and hematologic, serum biochemical, and electrocardiographic results were recorded, evaluated for association with mortality, and compared between institutions. RESULTS: Mortality did not differ between institutions, and overall mortality was 18% (24/137). Surgical techniques differed between institutions, but were not associated with mortality. Gastric necrosis was associated with significantly higher mortality (46%; 13/28). When partial gastrectomy or splenectomy was performed, mortality (35 and 32% or 8/23 and 10/31, respectively) was significantly increased. Splenectomy was performed in 11 of 23 dogs requiring partial gastrectomy, and when both procedures were performed, mortality (55%; 6/11) was significantly increased. Preoperative cardiac arrhythmias were associated with significantly higher mortality (38%; 6/16). Mortality in dogs > 10 years old was not significantly greater than that in younger dogs. CLINICAL IMPLICATIONS: Patient management differences between practices did not seem to influence survival in dogs with surgically managed gastric dilatation-volvulus. Signalment, including age, did not influence mortality. Gastric necrosis, gastric resection, splenectomy, and preoperative cardiac arrhythmias were associated with mortality > 30%.


Asunto(s)
Enfermedades de los Perros/mortalidad , Enfermedades de los Perros/cirugía , Dilatación Gástrica/veterinaria , Vólvulo Gástrico/veterinaria , Animales , Arritmias Cardíacas/complicaciones , Arritmias Cardíacas/veterinaria , Perros , Femenino , Dilatación Gástrica/complicaciones , Dilatación Gástrica/mortalidad , Dilatación Gástrica/cirugía , Masculino , Necrosis/veterinaria , Complicaciones Posoperatorias/veterinaria , Estudios Retrospectivos , Factores de Riesgo , Esplenectomía/veterinaria , Estómago/patología , Estómago/cirugía , Vólvulo Gástrico/complicaciones , Vólvulo Gástrico/mortalidad , Vólvulo Gástrico/cirugía , Vómitos/veterinaria
16.
J Am Vet Med Assoc ; 207(4): 460-4, 1995 Aug 15.
Artículo en Inglés | MEDLINE | ID: mdl-7591946

RESUMEN

Two hundred ninety-five case records were included in an analysis of dogs treated by a standardized protocol for gastric dilatation/volvulus syndrome between 1986 and 1992. A breed predisposition was demonstrated for Great Danes, German Shepherd Dogs, large mixed-breed dogs, and Standard Poodles. One hundred and ninety-three dogs had gastric dilatation and volvulus (GDV) confirmed at surgery, 66 had simple gastric dilatation (GD), and 36 others had gastric dilatation but volvulus could not be proved or disproved (GD +/- V). Among dogs with GDV, the fatality rate was 15% (29/193). Twenty-six (13.5%) dogs with GDV underwent partial gastrectomy, and 8 (31%) died or were subsequently euthanatized. In comparing the group of dogs with GDV that survived to those that died, there were no statistical differences in the age of dog, time between onset of clinical signs and admission, time from admission to surgery, or duration of anesthesia. Cardiac arrhythmias were detected in 40% (78/193) of the dogs with GDV. There also was no statistical correlation between development of a cardiac arrhythmia and outcome in dogs with GDV. The causes of death in dogs with GDV were multiple and varied; presumed gastric necrosis was a common reason for intraoperative euthanasia (11 dogs). Among dogs with GD or GD +/- V, the fatality rate was 0.9% (1/102).


Asunto(s)
Enfermedades de los Perros/terapia , Dilatación Gástrica/veterinaria , Vólvulo Gástrico/veterinaria , Animales , Cruzamiento , Cuidados Críticos , Enfermedades de los Perros/mortalidad , Perros , Femenino , Dilatación Gástrica/mortalidad , Dilatación Gástrica/terapia , Masculino , Necrosis , Pronóstico , Estudios Retrospectivos , Estómago/patología , Estómago/cirugía , Vólvulo Gástrico/mortalidad , Vólvulo Gástrico/terapia , Síndrome
17.
Acta Vet Scand ; 36(2): 175-84, 1995.
Artículo en Inglés | MEDLINE | ID: mdl-7484545

RESUMEN

A retrospective study of 103 dogs with gastric dilatation-volvulus (GDV) treated conservatively during the period 1985-1989 was performed. The date and number of recurrences, and the date and cause of death along with breed, age and sex were collected from clinic records and from a questionnaire sent to the owners (77% response). The treatment consisted of emptying the stomach with a stomach tube, gastrocentesis if necessary and treating shock. All of the affected dogs were from moderate to large sized breeds and the study showed that particular breeds appear to be predisposed to GDV. The average age was 7.2 years and there was no gender predisposition. Sixty-six per cent of the dogs survived the initial treatment and 50% of the dogs were still alive 1 month after treatment. Thirty-nine dogs (71%) received recurrence between 5-760 days after initial treatment. Fifty-six per cent had recurrence within 3 months and all except 2 dogs, within 1 year. Data for the time of death, regardless of cause, was available for 68 dogs. Of these 59 (81%) died within a year after initial treatment. Conservative treatment was found to be an adequate life-saving procedure in the acute stage of GDV, but could not alone prevent recurrence of the disease.


Asunto(s)
Enfermedades de los Perros/terapia , Dilatación Gástrica/veterinaria , Vólvulo Gástrico/veterinaria , Distribución por Edad , Animales , Enfermedades de los Perros/mortalidad , Perros , Femenino , Dilatación Gástrica/complicaciones , Dilatación Gástrica/terapia , Vaciamiento Gástrico , Masculino , Recurrencia , Estudios Retrospectivos , Distribución por Sexo , Especificidad de la Especie , Vólvulo Gástrico/complicaciones , Vólvulo Gástrico/mortalidad , Vólvulo Gástrico/terapia , Análisis de Supervivencia , Factores de Tiempo , Resultado del Tratamiento
18.
J Am Vet Med Assoc ; 204(9): 1465-71, 1994 May 01.
Artículo en Inglés | MEDLINE | ID: mdl-8050972

RESUMEN

The Veterinary Medical Data Base was usd to conduct an epidemiologic study of gastric dilatation and dilatation-volvulus (GDV) to describe changes over time in frequency of canine hospital admissions, to identify risk factors, and to estimate their relative importance. Cases in this case-control study included 1,934 dogs with GDV that were admitted to 12 participating veterinary hospitals from 1980 to 1989. The controls were 3,868 dogs with other diagnoses that were randomly selected from the same hospitals. Frequency of GDV per 1,000 canine hospital admissions ranged from 2.9 to 6.8. The case fatality rate was 28.6 and 33.3% for gastric dilatation alone and for gastric dilatation with volvulus, respectively. Using logistic regression analysis, the odds ratio (OR) and its 95% confidence limits (95% CL) for GDV associated with purebred vs mixed-breed dogs were 2.5 and 2.1, 3.0, respectively. The risk of GDV was associated with increasing age (chi 2 = 305.6, P < 0.0001) and increasing weight (chi 2 = 627.8, P < 0.0001). Significant association of GDV risk with sex or neuter status was not found. The 5 breeds having at least 10 cases and 8 controls and with the highest risk of GDV were Great Dane (OR, 10.0; 95% CL, 6.4, 15.6), Weimaraner (OR, 4.6; 95% CL, 2.3, 9.2), Saint Bernard (OR, 4.2; 95% CL, 2.3, 7.4), Gordon Setter (OR, 4.1; 95% CL, 1.8, 9.3), and Irish Setter (OR, 3.5; 95% CL, 2.4, 5.0). The effect of increasing body weight on GDV risk was less than that of increasing ideal adult breed weight, determined by published breed standards.(ABSTRACT TRUNCATED AT 250 WORDS)


Asunto(s)
Enfermedades de los Perros/epidemiología , Dilatación Gástrica/veterinaria , Vólvulo Gástrico/veterinaria , Factores de Edad , Animales , Peso Corporal , Cruzamiento , Estudios de Casos y Controles , Castración/veterinaria , Bases de Datos Factuales , Enfermedades de los Perros/mortalidad , Perros , Femenino , Dilatación Gástrica/complicaciones , Dilatación Gástrica/epidemiología , Dilatación Gástrica/mortalidad , Masculino , Análisis de Regresión , Factores de Riesgo , Factores Sexuales , Vólvulo Gástrico/complicaciones , Vólvulo Gástrico/epidemiología , Vólvulo Gástrico/mortalidad , Estados Unidos/epidemiología
19.
Br J Surg ; 77(12): 1379-81, 1990 Dec.
Artículo en Inglés | MEDLINE | ID: mdl-2276024

RESUMEN

From 1981 to 1988, 138 patients with hiatal hernia were treated surgically at our centre. Twenty-one (mean age 76.6 years, 17 women, four men) had an associated intrathoracic gastric volvulus. Eleven patients (mean age 73.2 years), of whom eight were asymptomatic, had an elective procedure. Ten patients (mean age 80.3 years) had emergency surgery, six for acute complications of the volvulus (five cases of strangulation and one of perforated ulcer) and four because of other, unrelated causes of acute abdomen. There were four deaths after operation, all in the emergency surgery group. Four other patients had significant morbidity, all in the emergency group. In the elective cases, all hernias were easily reduced. In one emergency case a gastrotomy was necessary for decompression, and in another gastrectomy was necessary because of gastric gangrene. Our results indicate the need for elective intervention when intrathoracic gastric volvulus is first diagnosed.


Asunto(s)
Hernia Hiatal/cirugía , Vólvulo Gástrico/cirugía , Anciano , Anciano de 80 o más Años , Urgencias Médicas , Femenino , Hernia Hiatal/complicaciones , Humanos , Masculino , Complicaciones Posoperatorias/etiología , Factores de Riesgo , Vólvulo Gástrico/etiología , Vólvulo Gástrico/mortalidad
20.
Tijdschr Diergeneeskd ; 112(19): 1101-5, 1987 Oct 01.
Artículo en Holandés | MEDLINE | ID: mdl-3672469

RESUMEN

Increased mortality occurred among sows in a pig-breeding unit during a few months. It was concluded that gastric torsion was one of the causes of death. This disease is becoming increasingly important in large intensive units, also in the Netherlands. Little is so far known of the origin of this syndrome. The feeding system and the quality of the food (fine-grained feed, contamination by toxic agents) could be a factor in the pathogenesis. Closer investigation of this economic problem would appear to be advisable.


Asunto(s)
Dilatación Gástrica/veterinaria , Vólvulo Gástrico/veterinaria , Enfermedades de los Porcinos/mortalidad , Animales , Conducta Alimentaria , Femenino , Dilatación Gástrica/mortalidad , Vólvulo Gástrico/mortalidad , Porcinos , Síndrome
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