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Braz. j. biol ; 84: e246463, 2024. tab
Artículo en Inglés | LILACS, VETINDEX | ID: biblio-1355899


Abstract Quilombola communities are present in many Brazilian states living in precarious health conditions. This is due to geographic isolation, limitations to the access of the area in which they live in, and the lack of quality in the service when it is needed to be provided. Therefore, the aim of this study was to analyze the quality of life of women from a quilombola community in northeastern Brazil. It is an observational, cross-sectional and descriptive study. 160 adult women were first interviewed through a form to collect a profile and then it was applied the WHOQOL Quality of Life questionnaire - bref. It was observed that the women were on average 40.7 years old (±17.25), married, self-declared black, who did not finish elementary school, housewife, had no income, with their own masonry house, with up to 6 rooms, supplied by a box of community treated water. Quality of Life had median scores in the domains: physical (3.18), psychological (3.4), social relationships (3.45) and environment (2.59). With this research, it was possible to characterize the quilombola community of Santa Luzia do Norte-AL regarding the difficulties of access to health and income generation, issues that affect their health condition. The problems described in this study can contribute to health actions being planned and carried out in order to improve socioeconomic and health conditions in this community, considering the social, political and environmental context, valuing their traditional knowledge and practices.

Resumo As comunidades quilombolas, estão presentes em diversos estados brasileiros, vivendo em condições de saúde mais precárias. Isto ocorre por conta do isolamento geográfico, das limitações de acesso e da falta de qualidade no serviço quando este é prestado. Nesse sentido, o objetivo do estudo foi analisar a qualidade de vida de mulheres de uma comunidade quilombola do nordeste brasileiro. Estudo observacional, transversal e descritivo. Foram entrevistadas 160 mulheres adultas, através de um formulário para a coleta de perfil e do questionário de Qualidade de Vida WHOQOL - bref. Foi observado que as mulheres tinham em média 40,7 anos (±17,25), casadas, autodeclaradas negras, com fundamental incompleto, do lar, sem renda, com moradia de alvenaria, própria, com até 6 cômodos, abastecidas por caixa de água comunitária, tratada. A Qualidade de Vida, apresentou escores medianos nos domínios: físico (3,18), psicológico (3,4), relações sociais (3,45) e meio ambiente (2,59). Com a realização desta pesquisa foi possível caracterizar a comunidade quilombola de Santa Luzia do Norte-AL quanto as dificuldades de acesso a saúde e geração de renda, fatos que repercutem na sua condição de saúde. Os problemas descritos neste estudo podem contribuir para que ações de saúde sejam planejadas e efetivadas com o intuito de melhorar as condições socioeconômicas e de saúde nessa comunidade, considerando-se o contexto social, político e ambiental, valorizando seus saberes e práticas tradicionais.

Humanos , Femenino , Adulto , Calidad de Vida , Brasil , Estudios Transversales , Encuestas y Cuestionarios
Arch Argent Pediatr ; 121(1): e202202595, 2023 02 01.
Artículo en Inglés, Español | MEDLINE | ID: mdl-35984671


Introduction. In Argentina, health care workers have been the first ones to receive the COVID-19 vaccine, but there are still few data on the production of anti-S IgG antibodies. Objectives. To assess specific IgG against the SARS-CoV-2 spike protein (anti-S IgG) after the vaccination of health care workers from a children's hospital. To explore the association between the presence of these antibodies, age, and history of prior infection. Population and methods. Cross-sectional study in 193 workers who received both doses of the two- component Sputnik V vaccine. The anti-S IgG antibody titer was measured and age, history of prior SARS-CoV-2 infection, and date of vaccination were recorded. Results. Anti-S IgG antibodies were produced in 98.6% of the subjects. The titer was higher in those with prior infection (p < 0.001), but no relationship was established with subjects' age. Conclusion. We provide data on post-vaccination production of IgG anti-S antibodies among health care workers from a children's hospital and explore some predictors.

Introducción. En Argentina, el personal de salud ha sido el primero en vacunarse contra COVID-19, pero todavía existen pocos datos sobre la producción de anticuerpos IgG anti-S. Objetivos. Evaluar IgG específica contra glicoproteína spike del SARS-CoV-2 (IgG anti-S) posvacunación en personal de un hospital pediátrico. Explorar la asociación entre presencia de dichos anticuerpos, edad y antecedente de infección previa. Población y métodos. Estudio transversal que incluyó 193 trabajadores vacunados con los dos componentes de la vacuna Sputnik V. Se pesquisó el título de IgG anti-S y se registraron edad, antecedente de infección previa por SARS-CoV-2 y fecha de la vacunación. Resultados. El 98,6 % de los sujetos generó IgG anti-S. El título fue mayor en quienes habían cursado infección previamente (p <0,001), pero no hubo relación con la edad de los sujetos. Conclusión. Aportamos datos de generación de anticuerpos IgG anti-S posvacunación en personal de salud de un hospital pediátrico y exploramos algunos predictores.

COVID-19 , Personal de Salud , SARS-CoV-2 , Anticuerpos Antivirales , COVID-19/inmunología , Vacunas contra la COVID-19 , Estudios Transversales , Hospitales Pediátricos , Humanos , Inmunoglobulina G , SARS-CoV-2/inmunología , Glicoproteína de la Espiga del Coronavirus
Braz. j. oral sci ; 22: e237434, Jan.-Dec. 2023. ilus
Artículo en Inglés | LILACS, BBO | ID: biblio-1393428


Aim: To determine the prevalence of dental development anomalies and type of influence on the smile of adolescent students. Method: This was a cross-sectional and analytical study carried out in two public (A1) and two private (A2) schools chosen by lot in the city of Parnaíba-Piauí. The sample calculation was based on the target population: number of people enrolled in public and private schools between 15 and 19 years, in the city of Parnaíba-PI, which totaled 6209 students in 2020, according to a survey carried out by the Brazilian Institute of Geography and Statistics ­ IBGE. A questionnaire on epidemiological data and aesthetic self-perception of the smile was applied to 160 adolescents between 15 and 19 years old, from August 2020 to July 2021. The clinical examination was carried out under natural light, to check for the presence of anomaly(s) in the dental development. Students who presented only one pathology would be called group 1 (G1), those who presented two would be called group 2 (G2) and those who presented 3 or more would be called group 3 (G3). On the other hand, adolescents in whom no anomaly was evidenced would participate in the control group (CG), both in A1 and A2. Results: It was observed that 37.5% of the sample had only a type of dental anomaly, corresponding to 60 individuals. The most prevalent were enamel hypoplasia, fusion, transposition, agenesis, ectopic eruption, microdent and dens-in-dent. It was possible to verify a higher prevalence in the maxilla, private schools (76.6%) and females (86.6%). In 45% of adolescents with dental anomalies, embarrassment was observed when smiling. Conclusion: The prevalence was relatively high, highlighting the enamel hypoplasia, influencing the smile esthetics of a reasonable number of adolescents, whether for acquaintances, strangers or even for photographs

Humanos , Masculino , Femenino , Adolescente , Adulto , Sonrisa , Anomalías Dentarias/epidemiología , Estudios Transversales , Encuestas y Cuestionarios , Esmalte Dental/anomalías , Diagnóstico Bucal , Estética Dental
Braz. j. biol ; 83: e248778, 2023. tab, graf
Artículo en Inglés | LILACS, VETINDEX | ID: biblio-1339371


Abstract This study aimed to analyze the socio-environmental characteristics, executive and nutritional functions in children aged 6 to 7 years, from public schools in Alagoas, Brazil. A quantitative, cross-sectional and descriptive study was performed involving 64 children of the mentioned age group, from public schools located in Alagoas: Maceió, on the coast; Major Isidoro, in the hinterland and Palmeira dos Índios, in the country. Such analyzes were made through the application of neuropsychological tests and anthropometric assessment with children and food and socio-environmental surveys with their parents. As for the type of housing, 100% were made of masonry, with a bathroom present in 98.4%. All children reported with the habit of bathing in the river / lagoon, presented some pathology. There was no significant difference between cities in terms of the sociodemographic characteristics evaluated, with the same result occurring with the factors associated with the occurrence of diseases in children. The subtests of WISC-IV, were below the average in all municipalities, and the TAC and SCC were classified within the average. However, even though the ranking were divided between below average and average, it is possible to identify from the subtests of WISC-IV, that the general IQ showed a cognitive level below the average. There was also no significant difference in the anthropometric assessment (weight, height, BMI and IMCI) between the evaluated students. The average weight was 23.3 kg to 25 kg, the height between 1.23 m to 1.24 m, the BMI between 16.4 to 17; the IMCI from 2.8 to 3.0. Children were classified within the average. Regarding micronutrients (Ca, Fe, K, Mg and Na, and vitamins A, C, D, B1, B9 and B12) and calories, there was also no significant difference between the cities evaluated. The same occurred with macronutrients (proteins, carbohydrates and lipids). This study showed that in general there was no difference between the students of the three municipalities. Probably, even though they are all public schools and from different cities, children have similar social conditions.

Resumo Este estudo teve como objetivo analisar as características socioambientais, funções executivas e nutricionais de crianças de 6 a 7 anos, de escolas públicas de Alagoas, Brasil. Foi realizado um estudo quantitativo, transversal e descritivo envolvendo 64 crianças, na referida faixa etária, de escolas públicas localizadas em Alagoas: Maceió, no litoral; Major Isidoro, no sertão e Palmeira dos Índios, no país. Tais análises foram feitas por meio da aplicação de testes neuropsicológicos e avaliação antropométrica com crianças e inquéritos alimentares e socioambientais com seus pais. Quanto ao tipo de habitação, 100% eram de alvenaria, com banheiro presente em 98,4%. Todas as crianças relataram o hábito de tomar banho no rio / lagoa, apresentavam alguma patologia. Não houve diferença significativa entre os municípios quanto às características sociodemográficas avaliadas, ocorrendo o mesmo resultado com os fatores associados à ocorrência de doenças em crianças. Os subtestes do WISC-IV, ficaram abaixo da média em todos os municípios, e o TAC e SCC foram classificados dentro da média. Porém, mesmo que a classificação tenha sido dividida entre abaixo da média e média, é possível identificar a partir dos subtestes do WISC-IV, que o QI geral apresentou um nível cognitivo abaixo da média. Também não houve diferença significativa na avaliação antropométrica (peso, altura, IMC e AIDPI) entre os alunos avaliados. O peso médio foi de 23,3 kg a 25 kg, a altura entre 1,23 ma 1,24 m, o IMC entre 16,4 a 17; A AIDPI de 2.8 a 3.0. As crianças foram classificadas dentro da média. Em relação aos micronutrientes (Ca, Fe, K, Mg e Na e vitaminas A, C, D, B1, B9 e B12) e calorias, também não houve diferença significativa entre os municípios avaliados. O mesmo ocorreu com os macronutrientes (proteínas, carboidratos e lipídios). Este estudo mostrou que de maneira geral não houve diferença entre os alunos dos três municípios. Provavelmente, mesmo sendo todas escolas públicas e de diferentes cidades, as crianças têm condições sociais semelhantes.

Humanos , Niño , Ingestión de Energía , Función Ejecutiva , Sodio , Brasil , Estudios Transversales
Braz. j. biol ; 83: e249911, 2023. tab, graf
Artículo en Inglés | LILACS, VETINDEX | ID: biblio-1339366


Abstract Hematological and hematopoietic cells malignancies of the genes and hematopoietic cells are associated with the genetic mutation, often at the chromosomal level. The standard cytogenetic study is widely accepted as one of the main diagnostics and prognostic determinants in patients. Therefore, the current descriptive and cross-sectional study sought to determine the cytogenetic analysis of frequent hematological malignancies in Pakistan. A total of 202 peripheral bone marrow or blood samples from patients with benign and malignant hematological malignancy were taken using a conventional G-banding technique. Among enrolled patients, the mean age was 21.5 years ± 23.4, and gender-wise distribution showed a marked predominance of the male 147 (73%) population compared to the female 55 (27%). Patients in the age group (2-10 years) had the highest frequency, 48 (24%), of hematological neoplasms, followed by age (11-20 years) with 40 (20%). Normal karyotypes (46, XX/46, XY) was found in 51% (n=103) patients. Furthermore, the frequency of complex karyotype was 30 (15%), while normal was seen in 171 (85%) patients. Pre-B Acute Lymphoblastic Leukemia (Pre-B ALL) was the most prevalent malignancy of 66 (33%), followed by Chronic Myelogenous Leukemia (CML) of 41 (20%) and Acute Lymphocytic Leukemia of 29 (14%). Translocation was the most prevalent 50 (25%), followed by hypotriploidy 14 (7%) and monosomy 8 (4%) on chromosome aberration analysis. In addition, t(9:22) translocation was found to be 20 (10%) in CML, with the majority in the age group (31-40 years). This study recommends that karyotyping should be tested frequently in hematological conditions because it may provide insight into the relative chromosomal changes associated with particular malignancies.

Resumo As neoplasias hematológicas e de células hematopoiéticas dos genes e as células hematopoiéticas estão associadas à mutação genética, geralmente em nível cromossômico. O estudo citogenético padrão é amplamente aceito como um dos principais determinantes diagnósticos e prognósticos em pacientes. Portanto, o presente estudo descritivo e transversal buscou determinar a análise citogenética de neoplasias hematológicas frequentes no Paquistão. Um total de 202 amostras de medula óssea periférica ou sangue de pacientes com malignidade hematológica benigna e maligna foi coletado usando uma técnica convencional de banda G. Entre os pacientes inscritos, a média de idade foi de 21,5 anos ± 23,4, e a distribuição por gênero mostrou uma marcada predominância da população masculina de 147 (73%) em comparação com a feminina de 55 (27%). Pacientes na faixa etária (2-10 anos) tiveram a maior frequência, 48 (24%), de neoplasias hematológicas, seguida da idade (11-20 anos) com 40 (20%). Cariótipos normais (46, XX / 46, XY) foram encontrados em 51% (n = 103) dos pacientes. Além disso, a frequência de cariótipo complexo foi de 30 (15%), enquanto normal foi observada em 171 (85%) pacientes. Leucemia linfoblástica aguda pré-B (LLA Pré-B) foi a doença maligna mais prevalente de 66 (33%), seguida por leucemia mieloide crônica (LMC) de 41 (20%) e leucemia linfocítica aguda de 29 (14%). A translocação foi o 50 mais prevalente (25%), seguido por hipotriploidia 14 (7%) e monossomia 8 (4%) na análise de aberração cromossômica. Além disso, a translocação t (9:22) encontrada foi de 20 (10%) na LMC, com a maioria na faixa etária (31-40 anos). Este estudo recomenda que o cariótipo deve ser testado com frequência em condições hematológicas porque pode fornecer informações sobre as alterações cromossômicas relativas associadas a doenças malignas específicas.

Humanos , Masculino , Femenino , Preescolar , Niño , Adolescente , Adulto , Adulto Joven , Aberraciones Cromosómicas , Neoplasias Hematológicas/genética , Neoplasias Hematológicas/epidemiología , Pakistán/epidemiología , Estudios Transversales , Cariotipificación
Braz. j. biol ; 83: e249209, 2023.
Artículo en Inglés | LILACS, VETINDEX | ID: biblio-1339360


Abstract Alo vera is a centenary remedy use for minor wounds and burns, but its mechanism of wound healing has not been know since. This article will evaluate and gather evidence of the effectiveness and safety of the use of aloe vera in the treatment of burns. A systematic review was carried out on the databases: MEDLINE, LILACS, DECS, SCIELO, in the last 7 years, with the descriptors: "Aloe", "Burns" and "treatment". 16 articles were found. After using the exclusion criteria; research in non-humans and literature review; 5 articles were selected. The article Teplick et al. (2018) performed an in vitro clinical experiment in A. Vera solution, and demonstrated that there was proliferation and cell migration of human skin fibroblasts and keratinocytes, in addition to being protective in the death of keratonocytes. That is, it accelerates the healing of wounds. Muangman et al. (2016), evaluated 50 patients with 20% of the total body surface area burned with second-degree burns, between 18-60 years old, with half of the group receiving gauze dressings with soft paraffin containing 0.5% chlorhexidine acetate and the other half receiving polyester dressings containing extracts of medicinal plants mainly Aloe Vera. It had positive results, a higher healing speed and shorter hospital stay compared to the control group. Hwang et al. (2015) investigated the antioxidant effects of different extracts from 2,4,6,8,12 months of Aloe Vera. And the 6-month concentrated extract of 0.25 mg / mL had a higher content of flavonoids (9.750 mg catechin equivalent / g extract) and polyphenols (23.375 mg gallic acid equivalent / g extract) and the greater ferric reducing antioxidant power (0.047 mM equivalent ferrous sulfate / mg extract), that is, greater potential for free radical scavenging and also a protective effect against oxidative stress induced by tert-butyl hydroperoxide (t-BHP), suggesting evidence of a bioactive potential of A. vera . However, in the article Kolacz et al. (2014) suggested as an alternative treatment the use of Aloe Vera dressing in combination with honey, lanolin, olive oil, wheat germ oil, marshmallow root, wormwood, comfrey root, white oak bark, lobelia inflata, glycerin vegetable oil, beeswax and myrrh, without obtaining significant and conclusive results that would allow the conventional treatment of burns to be subsidized. Finally, in the article by Zurita and Gallegos (2017), it carried out a descriptive cross-sectional study with 321 people, both sexes between 17-76 years of age, of an inductive nature, exploring the experience of this population and their behavioral attitudes regarding the treatment of dermatoses. Aloe vera had 13.8% cited by individuals in the treatment of acne and 33.6% in the treatment of burns. Even with evidence that suggests the efficacy in the treatment of burns with the use of Aloe Vera extract, further clinical trials with larger sample space on the use of Aloe vera dressings in medium burns are suggested for further conclusions.

Resumo Alo vera é um remédio centenário usado para pequenas feridas e queimaduras, mas seu mecanismo de cicatrização de feridas não foi conhecido desde então. Este artigo avaliará e reunirá evidências da eficácia e segurança do uso de aloe vera no tratamento de queimaduras. Realizada revisão Sistemática nas bases de dados: MEDLINE, LILACS, DECS, SCIELO, nos últimos 7 anos, com os descritores: "Aloe", "Burns" and "treatment". Foram encontrados 16 trabalhos. Após utilizarmos os critérios de exclusão; pesquisa em nao humanos e revisão da literatura ; foram selecionados 5 artigos. O artigo Teplick et al. (2018) realizou um experimento clinico in vitro em solução de A. Vera, e demonstrou que houve proliferação e migração celular de fibroblastos e queratinócitos de pele humana, além de ser protetor na morte de queratonócitos. Ou seja, acelera a cicatrização das feridas. Já Muangman et al. (2016), avaliou 50 pacientes com 20% do total da área superficial corporal queimada com queimaduras de segundo grau, entre 18-60 anos, tendo metade do grupo como controle recebendo curativos de gaze com parafina mole contendo 0,5% acetado de clorexidina e a outra metade recebendo curativos com poliéster contendo extratos de plantas medicinais principalmente Aloe Vera. Teve resultados positivos, uma maior velocidade de cicatrização e menor tempo de internação comparado ao grupo controle. Já Hwang et al. (2015) investigou os efeitos antioxidante de diferentes extratos de 2,4,6,8,12 meses da Aloe Vera. E o extrato com 6 meses concentrado de 0,25 mg/mL teve maior teor de flavanóides (9,750 mg equivalente catequina / g extrato) e polifenóis (23,375 mg equivalente ácido gálico / g extrato) e o maior poder antioxidante redutor férrico (0,047 mM de sulfato ferroso equivalente / extrato mg), ou seja, maior potencial de eliminação de radicais livres e também efeito proteror contra o estresse oxidativo induzido por hidroperóxido de terc-butila (t-BHP), sugerindo indícios de um potencial bioativo da A. vera. Porém, no artigo Kolacz et al. (2014) sugeriu como tratamento alternativo o uso do curativo com Aloe Vera em conjunto de mel, lanolina, azeite de oliva, óleo de gérmen de trigo, raiz de marshmallow, absinto, raiz de confrei, casca de carvalho branco, lobelia inflata, glicerina vegetal, cera de abelha e mirra, não obtendo resultados significativos e conclusivos que permitam subsidiar o tratamento convencional das queimaduras. Por fim, no artigo de Zurita and Gallegos (2017), realizou um estudo descritivo transversal com 321 pessoas, ambos os sexos entre 17-76 anos, de natureza indutiva, explorando a vivência dessa população e suas atitudes comportamentais quanto ao tratamento de dermatoses. Aloe vera teve 13,8% citada pelos indivíduos no tratamento de acne e 33,6% no tratamento de queimaduras. Mesmo tendo evidências que sugerem a eficácia no tratamento de queimaduras com o uso do extrato da Aloe Vera, sugere-se mais ensaios clínicos com espaço amostral maior sobre o uso de curativos de Aloe vera em médio queimados para maiores conclusões.

Humanos , Plantas Medicinales , Quemaduras/tratamiento farmacológico , Aloe , Cicatrización de Heridas , Extractos Vegetales/uso terapéutico , Extractos Vegetales/farmacología , Estudios Transversales
Braz. j. biol ; 83: e246514, 2023. tab, graf
Artículo en Inglés | LILACS, VETINDEX | ID: biblio-1285640


Abstract The poultry sector in Pakistan is contributing mainly in bridging gap between demand and supply for protein. Mycoplasma gallisepticum is an emerging bacterium causing serious problems in poultry industry of Pakistan. A cross-sectional study was conducted to evaluate the M. gallisepticum load in poultry populated regions of Pakistan. Total 600 serum and 600 swab samples were collected, 200 from each broiler, layers and breeders poultry in Rawalpindi and Abbottabad districts. Serum samples were analyzed through ELISA for seroprevalence. Swabs were cultured on Frey's medium followed by PCR and partial mgc2 gene sequencing. Results of seroprevalence of M. gallisepticum showed that layers (75%, n=150) are more positive as compared to breeders (70%, n=140) and broilers (50%, n=100). Typical colonies of the M. gallisepticum were observed in breeder (26.5%), followed by layer (21%) and broilers (9%). A total of 37.1% (n=42) samples were identified positive through PCR out of total 113 cultured based positive samples. A total of six M. gallisepticum isolates of current study showed 98-99 percent similarity with previously reported isolates on the basis of mgc2 gene partial sequencing. The M. gallisepticum was found highly prevalent in different poultry breads. Results of this study would add into basic data and provide a direction for livestock sector to strengthen a control strategy for mycoplasmosis in poultry farms.

Resumo O setor avícola do Paquistão está contribuindo principalmente para preencher a lacuna entre a demanda e a oferta de proteína. Mycoplasma gallisepticum é uma bactéria emergente que causa sérios problemas na indústria avícola do Paquistão. Um estudo transversal foi conduzido para avaliar a carga de M. gallisepticum em regiões de avicultura do Paquistão. Um total de 600 amostras de soro e 600 amostras de esfregaço foi coletado, 200 de cada frango de corte, poedeiras e aves reprodutoras nos distritos de Rawalpindi e Abbottabad. Amostras de soro foram analisadas por ELISA para soroprevalência. As zaragatoas foram cultivadas em meio Frey, seguido de PCR e sequenciação parcial do gene mgc2. Os resultados da soroprevalência de M. gallisepticum mostraram que as poedeiras (75%, n = 150) são mais positivas em comparação com matrizes (70%, n = 140) e frangos de corte (50%, n = 100). Colônias típicas de M. gallisepticum foram observadas em reprodutoras (26,5%), seguidas de poedeiras (21%) e frangos de corte (9%). Um total de 37,1% (n = 42) das amostras foi identificado como positivas por PCR de um total de 113 amostras positivas baseadas em cultura. Um total de seis isolados de M. gallisepticum do estudo atual mostrou 98-99% de similaridade com isolados relatados anteriormente com base no sequenciamento parcial do gene mgc2. O M. gallisepticum foi encontrado com alta prevalência em diferentes pães de aves. Os resultados deste estudo acrescentariam dados básicos e forneceriam orientação para o setor pecuário fortalecer uma estratégia de controle da micoplasmose em granjas avícolas.

Animales , Enfermedades de las Aves de Corral/epidemiología , Mycoplasma gallisepticum/genética , Pakistán/epidemiología , Aves de Corral , Estudios Seroepidemiológicos , Pollos , Estudios Transversales
Horm Metab Res ; 54(2): 67-75, 2022 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-35130567


Resistance to thyroid hormone syndrome (RTHS) is defined as increased thyroxine and triiodothyronine associated with normal or increased thyrotropin. This is usually due to a pathogenic variant of the gene coding for thyroid hormone receptor B (THRB). THRB is a rare genetic disorder characterized by an altered response of target tissue to the thyroid hormone action. Retrospective cross-sectional observational study with diagnosis of RTHS evaluated in secondary and tertiary hospitals for 6 years, from 2014 to 2020, in order to describe variables including age, sex, anthropometric data, clinical and biochemical characteristics of patients, who were divided according to age, in a pediatric group from 0 to 14 years (index cases), and an adult group composed of adult relatives of index cases. A molecular analysis of the THRB gene was performed. The total retrospective cohort included 7 pediatric patients and 15 adults. We found 22 cases with a clear male predominance (14/22). Mean age is 24.8 years old (22 days-70 years). Patients were referred because of symptoms 18.2% (4/22), analysis results 22.7% (5/22), or familial study 59.1% (13/22). About 31.8% (7/22) cases show goiter, 31.8% (7/22) sympathetic symptoms and 13.6% (3/22) abnormalities in behavior. In most cases, 77.3%, (17/22) show familial background of thyroid abnormalities. It is important to remark that 18.2% (4/22) relatives received previous incorrect treatments such as thyroidectomy, because of wrong diagnosis. In conclusion, a better understanding of RTHS, its prompt molecular diagnosis and genetic counseling, could avoid unnecessary tests and inappropriate treatments.

Síndrome de Resistencia a Hormonas Tiroideas , Adolescente , Adulto , Niño , Preescolar , Estudios Transversales , Humanos , Lactante , Recién Nacido , Masculino , Mutación , Estudios Retrospectivos , Receptores beta de Hormona Tiroidea/genética , Síndrome de Resistencia a Hormonas Tiroideas/diagnóstico , Síndrome de Resistencia a Hormonas Tiroideas/genética , Tirotropina , Tiroxina , Triyodotironina , Adulto Joven
Horm Metab Res ; 54(2): 104-112, 2022 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-35130571


Some studies have suggested that diabetes may be a risk factor for osteoarthritis. However, whether prediabetes is also associated with osteoarthritis has not been comprehensively examined. We performed a meta-analysis to evaluate the relationship between prediabetes and osteoarthritis. This meta-analysis included relevant observational studies from Medline, Embase, and Web of Science databases. A random-effect model after incorporation of the intra-study heterogeneity was selected to pool the results. Ten datasets from six observational studies were included, which involved 41 226 general adults and 10 785 (26.2%) of them were prediabetic. Pooled results showed that prediabetes was not independently associated with osteoarthritis [risk ratio (RR): 1.07, 95% confidence interval (CI): 1.00 to 1.14, p=0.06, I2=0%]. Sensitivity limited to studies with adjustment of age and body mass index showed consistent result (RR: 1.06, 95% CI: 0.99 to 1.14, p=0.09, I2=0%). Results of subgroup analyses showed that prediabetes was not associated with osteoarthritis in cross-sectional or cohort studies, in studies including Asian or non-Asian population, or in studies with different quality scores (p for subgroup difference>0.10). Besides, prediabetes was not associated with osteoarthritis in men or in women, in studies with prediabetes defined as impaired fasting glucose, impaired glucose tolerance, or HbA1c (approximately 39-46 mmol/mol). Moreover, prediabetes was not associated with overall osteoarthritis, and knee or hip osteoarthritis. Current evidence does not support that prediabetes is independently associated with osteoarthritis in adult population.

Intolerancia a la Glucosa , Osteoartritis , Estado Prediabético , Adulto , Glucemia/metabolismo , Estudios Transversales , Femenino , Hemoglobina A Glucada/análisis , Humanos , Masculino , Estudios Observacionales como Asunto , Osteoartritis/complicaciones , Osteoartritis/epidemiología , Estado Prediabético/complicaciones , Estado Prediabético/epidemiología , Estado Prediabético/metabolismo , Factores de Riesgo
Rev. urug. enferm ; 17(2): 1-12, dic. 2022.
Artículo en Español | LILACS, BDENF, BNUY, BNUY-Enf | ID: biblio-1391808


La alimentación adecuada es un derecho humano que contribuye a una buena calidad de vida de las personas y uno de sus componentes básicos es la accesibilidad. En el Plan de cuidados de Enfermería, se valora el proceso de envejecimiento y las modifi caciones que éste genera pudiendo contribuir a situaciones de vulnerabilidad desde el punto de vista nutricional. La accesibilidad a la alimentación se puede ver afectada por diferentes factores, como es el acceso físico, alimentos sufi cientes y adecuados, y las dificultades económicas. El objetivo fue conocer la accesibilidad en la alimentación de personas mayores (65 años y más) que residen en complejos habitacionales para jubilados y pensionistas. Se realizó un estudio de tipo cuantitativo de corte transversal. La recolección de los datos se llevó a cabo en tres complejos habitacionales para jubilados y pensionistas, seleccionados dos de ellos en la ciudad de Montevideo y uno en la ciudad de Rivera. La muestra estuvo conformada por 68 personas (69% de los residentes) que residen en los complejos.Los resultados demuestran que un 18% de esta población tiene dificultades en la accesibilidad en la alimentación, las causas fueron la falta de dinero en un 70% y un 30% por problema en la movilidad. Es reconocido en Uruguay el derecho a la alimentación y en generar políticas públicas y programas que contribuyan a satisfacer esta necesidad vital y garantizar el acceso a la misma, en grupos de población vulnerables como puede ser en las personas mayores.

Adequate food is a human right that contributes to a good quality of life for people and one of its basic components is accessibility. In the Nursing Care Plan, the aging process and the changes it generates are valued and may contribute to situations of vulnerability from the nutritional point of view. Accessibility to food can be affected by different factors, such as physical access, sufficient and adequate food, and economic difficulties. The objective was to know the accessibility in food of older people (65 years and over) who reside in housing complexes for retirees and pensioners. A quantitative cross-sectional study was carried out. Data collection was carried out in three housing complexes for retirees and pensioners, two of them selected in the city of Montevideo and one in the city of Rivera. The sample consisted of 68 people (69% of the residents) who reside in the complexes. The results show that 18% of this population has difficulties in food accessibility, the causes were lack of money in 70% and 30% due to mobility problems. The right to food is recognized in Uruguay and to generate public policies and programs that contribute to satisfying this vital need and guaranteeing access to it, in vulnerable population groups such as the elderly.

A alimentação adequada é um direito humano que contribui para uma boa qualidade de vida das pessoas e um de seus componentes básicos é a acessibilidade. No Plano de Assistência de Enfermagem, o processo de envelhecimento e as mudanças que ele gera são valorizados e podem contribuir para situações de vulnerabilidade do ponto de vista nutricional. A acessibilidade aos alimentos pode ser afetada por diversos fatores, como acesso físico, alimentação suficiente e adequada e dificuldades econômicas. O objetivo foi conhecer a acessibilidade na alimentação de pessoas idosas (65 anos ou mais) que residem em conjuntos habitacionais para aposentados e pensionistas. Foi realizado um estudo quantitativo transversal. A coleta de dados foi realizada em três conjuntos habitacionais para aposentados e pensionistas, dois deles selecionados na cidade de Montevidéu e um nacidade de Rivera. A amostra foi composta por 68 pessoas (69% dos moradores) que residem nos complexos. Os resultados mostram que 18% dessa população tem dificuldades na acessibilidade alimentar, as causas foram falta de dinheiro em 70% e 30% por problemas de locomoção. O direito à alimentação é reconhecido no Uruguai e para gerar políticas e programas públicos que contribuam para satisfazer esta necessidade vital e garantir o acesso a ela, em grupos populacionais vulneráveis como os idosos.

Humanos , Masculino , Femenino , Anciano , Anciano de 80 o más Años , Salud del Anciano Institucionalizado , Nutricion del Anciano , Acceso a Alimentos Saludables , Factores Socioeconómicos , Uruguay , Envejecimiento , Promoción de Salud Alimentaria y Nutricional , Estado Nutricional , Estudios Transversales , Cognición , Vulnerabilidad en Salud , Limitación de la Movilidad
Rev. urug. enferm ; 17(2): 1-20, dic. 2022.
Artículo en Español | LILACS, BDENF, BNUY, BNUY-Enf | ID: biblio-1392412


El contexto epidemiológico que se vive a nivel mundial desde el comienzo de la pandemia por COVID-19, puso de manifiesto factores de sobrecarga laboral en el personal de la salud, relacionados con la exposición diaria a situaciones que ponen en riesgo su integridad física y mental. Tomando en cuenta el valor social, la validez científica y el beneficio que se genera con la investigación en el campo de la salud, nos propusimos explorar y analizar en qué medida y en qué aspectos la situación de pandemia ha afectado las cargas en enfermería partiendo de la hipótesis de un aumento en la percepción de cargas desde el inicio de la pandemia por COVID-19. En función de los resultados obtenidos, elaboramos recomendaciones y una propuesta que contribuya al desarrollo de un entorno de trabajo saludable para el personal de enfermería, estableciendo medidas de prevención e intervención destinadas a minimizar los riesgos e incrementar la satisfacción laboral. Para el relevamiento de los datos se aplicó una encuesta online, anónima, auto administrada dirigida al personal de enfermería de Uruguay que trabaja en los tres niveles de atención, la cual nos permitió un acercamiento a los principales indicadores de carga física y mental. En términos absolutos se encuestaron 304 licenciados en enfermería y 677 auxiliares. Si se comparan los encuestados con el Registro de Habilitación del MSP (2017), la participación alcanzó el 3,29 % de la población total en enfermería. Se logró la cobertura de los 19 departamentos de Uruguay. Los resultados obtenidos, evidenciaron un incremento en la carga física y mental, a partir del contexto generado por COVID-19, relacionado principalmente con aspectos institucionales, alteraciones fisiológicas, psicoafectivas y sociofamiliares.

The epidemiological context that has been experienced worldwide since the beginning of the COVID-19 pandemic has revealed factors of work overload in health personnel, related to daily exposure to situations that put their physical and mental integrity at risk. Considering the social value, the scientific validity and the benefit generated by research in the field of health, we set out to explore and analyze to what extent and in what aspects the pandemic situation has affected nursing work load based on the hypothesis of an increase in the perception of burdens since the start of the COVID-19 pandemic. Based on the results obtained, we developed recommendations and a proposal that contributes to the development of a healthy work environment for nursing staff, establishing prevention and intervention measures aimed at minimizing risks and increasing job satisfaction. To collect the data, an online, anonymous, self-administered survey was applied to nursing staff in Uruguay who work at the three levels of care, which allowed us to approach the main indicators of physical and mental load. In absolute terms, 304 nursing graduates and 677 auxiliaries were surveyed. When we compare the respondents with the MSP Qualification Registry (2017), participation reached 3.29% of the total nursing population. Coverage of the 19 departments of Uruguay was achieved. The results showed an increase in the physical and mental load, based on the context generated by COVID-19, mainly related to institutional aspects, physiological, psycho-affective and socio-family alterations.

O contexto epidemiológico que se vive mundialmente desde o início da pandemia do COVID-19 tem revelado fatores de sobrecarga de trabalho nos profi ssionais de saúde, relacionados à exposição diária a situações que colocam em risco sua integridade física e mental. Levando em conta o valor social, a validade científica e o benefício gerado pela pesquisa na área da saúde, propusemo-nos a explorar e analisar em que medida e em que aspectos a situação pandêmica afetou as cargas de trabalho de enfermagem com base na hipótese de aumento na percepção de ônus desde o início da pandemia de COVID-19. Com base nos resultados obtidos, desenvolvemos recomendações e uma proposta que contribui para o desenvolvimento de um ambiente de trabalho saudável para a equipe de enfermagem, estabelecendo medidas de prevenção e intervenção paravive minimizar riscos e aumentar a satisfação no trabalho. Para coletar os dados, foi aplicada uma pesquisa online, anônima e autoadministrada aos profissionais de enfermagem do Uruguai que atuam nos três níveis de atenção, o que permitiu abordar os principais indicadores de carga física e mental. Em termos absolutos, foram pesquisados 304 egressos de enfermagem e 677 auxiliares. Se compararmos os respondentes com o Registro de Qualificação MSP (2017), a participação atingiu 3,29% do total da população de enfermagem. A cobertura dos 19 departamentos do Uruguai foi alcançada. Os resultados obtidos mostraram um aumento da carga física e mental, com base no contexto gerado pela COVID-19, principalmente relacionado a aspectos institucionais, alterações fisiológicas, psicoafetivas e sociofamiliares.

Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Riesgos Laborales , Carga de Trabajo , Estrés Laboral , COVID-19 , Personal de Enfermería , Uruguay , Condiciones de Trabajo , Agotamiento Profesional , Estudios Transversales , Encuestas y Cuestionarios , COVID-19/psicología
Arch. pediatr. Urug ; 93(2): e206, dic. 2022. tab
Artículo en Español | LILACS, BNUY, UY-BNMED | ID: biblio-1383653


Introducción: el intento de autoeliminación (IAE) y el suicidio han aumentado en adolescentes, es un problema de alta prioridad. Objetivo: establecer la epidemiología y su relación con factores de riesgo (FR) y protección (FP) de conducta suicida en usuarios de un Espacio Adolescente en el primer nivel de atención del subsector público (diciembre 2016-setiembre 2017). Material y método: encuesta anónima a adolescentes de ambos sexos, entre 12 y 19 años. Se compararon FR y FP entre: franjas etarias (12 a 14 años y 15 a 19 años); sexo; IAE previo versus su ausencia e institucionalización o no. Se consideró p menor a 0,05 como estadísticamente significativa. Los datos se ingresaron en Excel y se analizaron con Epi Info Resultados: 107 entrevistados, 60 mujeres, edad: 13,3 (media); IAE previo más frecuente entre 15 y 19 años y sexo femenino (p 95%). FP p 95%: actividad recreativa, autoestima elevada, y buena resolución de problemas. FR p 95%: maltrato, abuso sexual, muerte de ser querido, consumo de sustancias y enfermedad psiquiátrica. Comparando edades, FP: familia unida, proyectos y amigos (p 95%); FR: consumo de sustancias, enfermedad psiquiátrica, maltrato, abuso sexual, familiar con enfermedad psiquiátrica, muerte de ser querido, trastorno del sueño, institucionalización, ideación y planificación suicidas (p 95%). Al comparar sexos, no se encontraron FP p 95% FR. Conclusiones: se deben estimular actividades recreativas en adolescentes y ofrecer asistencia en salud mental a aquellos que presentan FR de conducta suicida.

Introduction: self-harm (SH) and suicide have increased in adolescents, and they have become a high health priority. Objective: to establish the epidemiology and its relationship with risk factors (RF) and protection (PF) of suicidal behavior in users of a Primary Care Adolescent Center of the State Health Sector (December 2016 - September 2017). Materials and methods: confidential survey of adolescents of both sexes, between 12 and 19 years of age. We carried out a descriptive analysis in order to compare RF and PF between ages (12 to 14 and 15 to 19); sex; previous SH self-harm versus its absence and institutionalization or not. p less than 0.05 was considered statistically significant. Data were entered into Excel and analyzed using Epi Info Results: 107 interviewees, 60 females, age: 13.3 (mean); Most frequent previous SH between 15 and 19 years and female sex (p 95%). PF p 95 %: recreational activity, high self-esteem, and good problem-solving skills. RF p 95 %: child abuse, sexual abuse, death of a loved one, substance use and mental illness. Comparing ages, PF: close family, projects and friends (p 95%); RF: substance use, mental illness, child abuse, sexual abuse, family with mental illness, death of loved one, sleep disorder, institutionalization, suicidal ideation and suicidal planning (p 95%). When comparing sexes, PF were not found p 95% as RF. Conclusions: recreational activities should be encouraged in adolescents and Mental Health assistance should be provided to those who present RF of suicidal behavior.

Introdução: tentativa de suicídio e suicídio tem aumentado na adolescência, adquirindo alta prioridade. Objetivo: estabelecer a epidemiologia e sua relação com fatores de risco (FR) e proteção (FP) de comportamento suicida em usuários do chamado "Espaço Adolescente" no Primeiro Nível de Atenção no Subsetor Público do Sistema de Saúde (dezembro 2016-setembro 2017). Materiais e métodos: inquérito anônimo aos adolescentes de ambos os sexos, entre 12 e 19 anos de idade. Foram comparados FR e FP entre: grupos de idades (12 a 14 e 15 a 19); sexo; tentativa de suicídio anterior versus sua ausência e institucionalização ou não. Considerou-se p menor a 0,05 como estatisticamente significativa. Os dados foram processados no programa Excel e utilizando-se o programa Epi Info Resultados: 107 entrevistados, 60 do sexo feminino, idade: 13,3 (média); antecedentes de tentativa de suicídio mais frequentes entre 15 e 19 anos e sexo feminino (p 95%). FP p 95%: atividade recreativa, autoestima elevada, e boas habilidades de resolução de problemas. FR p 95%: maltrato, abuso sexual, perda de pessoa querida, consumo de substâncias e doença psiquiátrica. Comparadas as idades, FP: família unida, projetos e amigos (p 95%); FR: consumo de substâncias, doença psiquiátrica, maltrato, abuso sexual, familiar com doença psiquiátrica, perda de pessoa querida, transtorno do sono, institucionalização, ideação suicida e planejamento suicida (p 95%). Comparados ambos os sexos, não se encontraram FP p 95% FR. Conclusões: atividades recreativas devem ser estimuladas nos casos de adolescentes e assistência à Saúde Mental deve ser fornecida aos portadores de FR suicida.

Humanos , Masculino , Femenino , Niño , Adolescente , Adulto Joven , Suicidio/estadística & datos numéricos , Atención Primaria de Salud , Uruguay/epidemiología , Estudios Transversales , Factores de Riesgo , Encuestas Epidemiológicas , Sector Público , Distribución por Sexo , Factores Protectores
Int J Public Health ; 67: 1604979, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36090824


Objectives: The study aimed at analyzing the prevalence of five psychological outcomes (depression, anxiety, stress, post-traumatic stress disorder (PTSD), and suicidal ideation) among Chinese healthcare workers (HCWs), and measured the total possible negative psychological impact 1 year after the COVID-19 initial outbreak. Methods: A cross-sectional nationwide multi-center study was performed between November 2020 and March 2021 in China. A self-report questionnaire was applied, and three psychological scales were used. Binary logistic regression was performed to analyze the risk factors associated with each psychological outcome. Results: The findings demonstrated that the COVID-19 pandemic had a negative psychological impact on HCWs, which was still evident 1 year after the initial outbreak. Nurses showed higher depression and anxiety than other HCWs. Female gender, passive coping, long working hours, having a chronic disease, and experiencing violence, among other factors, were all risk factors for psychological impairment. Conclusion: Developing and promoting programs to improve mental health among HCWs, and identifying those who might need psychological support is still relevant 1 year after the initial outbreak.

COVID-19 , COVID-19/epidemiología , China/epidemiología , Estudios Transversales , Brotes de Enfermedades , Femenino , Personal de Salud , Humanos , Pandemias
Int J Public Health ; 67: 1604885, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36090826


Objectives: Quarantine-related loneliness has impacted university students during the coronavirus disease 2019 (COVID-19) pandemic. This study aims to evaluate loneliness among female university students in Riyadh, Saudi Arabia during the pandemic and to investigate its correlation with depression. Methods: A sample of 753 female students was collected during the first COVID-19 summer vacation outbreak through a cross-sectional survey that consisted of two parts: 1) Sociodemographic characteristics and COVID-19 related questions; 2) The eight-item UCLA Loneliness Scale (ULS-8) and the Patient Health Questionnaire-9 (PHQ-9). Results: Most participants were between 18 and 22 years old (75.2%) and were studying at humanities college (61.50%). Loneliness and depression were reported among 63.3% and 41.1% of female students, respectively, and the correlation between them was significantly positive (beta = 0.419, p < 0.001). Having a previous history of a psychiatric condition and families with insufficient monthly income were the main associated factors with high levels of loneliness and depression. Conclusion: Female university students experienced loneliness and depression under quarantine during the first COVID-19 summer vacation outbreak. Psychosocial intervention for the vulnerable groups is essential, as are longitudinal studies.

COVID-19 , Soledad , Adolescente , Adulto , COVID-19/epidemiología , Estudios Transversales , Depresión/epidemiología , Depresión/psicología , Femenino , Humanos , Soledad/psicología , Pandemias , Arabia Saudita/epidemiología , Estudiantes/psicología , Universidades , Adulto Joven
Int J Public Health ; 67: 1605042, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36090827


Objective: To investigate predictors of life satisfaction and healthy aging with focus on gender differences among older people in Brunei Darussalam. Methods: A cross-sectional study on older people recruited by proportionate sampling. Multiple linear regression stratified by gender was applied. Results: 45.6% of life satisfaction of older women were strongly associated with self-perceived health, social relationship, and education level. For older men, 26.3% of the variance of life satisfaction was predicted by physical functioning or disability, and social relationship. For older women, 38.9% of the variance of health status can be explained with satisfaction with life, and difficulty to do daily tasks. For older men, 33.1% of the variance of health status can be accounted by income, number of children, presence of chronic illness, and diabetes. Conclusion: This paper discusses the unique gender differences of older people from a global perspective. Policymakers and stakeholders need to account for local and contextual differences before adopting international guideline. Particularly, on the maintenance or further promotion social interactions, active engaging elderly in health maintenance, and physical and mental functioning of the older population.

Personas con Discapacidad , Satisfacción Personal , Anciano , Brunei , Niño , Estudios Transversales , Femenino , Estado de Salud , Humanos , Masculino
Int J Public Health ; 67: 1604684, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36090832


Objectives: To record the prevalence and risk factors of substance use amongst homeless persons during the COVID-19 pandemic. Methods: The ECHO study consisted in two independent cross-sectional waves of data collection in the regions of Paris, Lyon, and Strasbourg during the Spring of 2020 (n = 530) and 2021 (n = 319). Factors associated with substance use were explored using generalised logistic regression models. Results: The most prevalent substance used was tobacco (38%-43%), followed by alcohol (26%-34%). The use of both substances positively associated with each other, although risk factors varied depending on the substance. The only factors consistently associated with alcohol and tobacco use were being male, exposure to theft/assault and participants' region of origin. Whilst the rate of tobacco use was relatively stable between Spring 2020 and 2021, alcohol use was more common in 2021. Conclusion: These findings highlight a high prevalence of substance use amongst homeless persons. People experiencing homelessness face specific challenges in the context of the pandemic, alongside greater vulnerability to illness and low healthcare access, therefore the need to improve prevention and support services for substance abuse within this population is vital.

COVID-19 , Personas sin Hogar , Trastornos Relacionados con Sustancias , COVID-19/epidemiología , Estudios Transversales , Femenino , Humanos , Masculino , Pandemias , Prevalencia , Trastornos Relacionados con Sustancias/epidemiología
Int J Public Health ; 67: 1604918, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36090834


Objectives: To understand the public's perceptions around rapid SARS-CoV-2 antigen self-testing in Kenya, including the drivers of acceptability, willingness to pay, and adherence to hygiene and prevention recommendations following a positive self-test. Methods: A household-based, cross-sectional survey, using a 35-item questionnaire, was conducted in Mombasa and Taita-Taveta counties, Kenya, during August 2021. Individuals aged ≥18 years were enrolled using a stratified sampling approach. Results: There were 419 participants (mean age 35.7 years). A minority (10.5%) had ever tested for SARS-CoV-2. If SARS-CoV-2 self-testing were available, 39.9% and 41.5% would be likely and very likely, respectively, to use it. If unavailable free-of-charge, 63.01% would pay for it. Multivariate analyses suggested that people in rural areas (Coefficient 0.30, 95%CI: 0.11-0.48, p = 0.002), aged 36-55 (Coefficient 0.21, 95%CI: 0.03-0.40, p = 0.023), and employed full time (Coefficient 0.32, 95%CI: 0.06-0.58, p = 0.016) would have more odds to adhere to recommended hygiene and prevention actions. Conclusion: SARS-CoV-2 self-testing was considered acceptable. Availability of self-testing could expand access to COVID-19 testing in Kenya, particularly among rural communities who have limited access to testing, and among mildly symptomatic individuals.

COVID-19 , Infecciones por VIH , Adolescente , Adulto , COVID-19/diagnóstico , COVID-19/prevención & control , Prueba de COVID-19 , Estudios Transversales , Humanos , Kenia , SARS-CoV-2 , Autoevaluación
Int J Public Health ; 67: 1605036, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36090838


Objective: To assess the associations between parents' working conditions during the lockdown period (March-May 2020) and children's health-related quality of life (HRQOL) over the first year of the COVID-19 pandemic in Zurich, Switzerland. Methods: We included 2211 children (6-16 years) and their parents from the prospective study Ciao Corona. Parents reported their employment status and working conditions during the lockdown. Children's HRQOL was assessed in June-July 2020, January and March 2021 using the parents-report of the KINDL®. We used mixed models to assess the associations between parents' working conditions and children's HRQOL at the three time points. Results: Children from families in which at least one parent changed their working conditions during the lockdown showed lower HRQOL in June-July 2020, than children from families in which neither parent experienced changes. Children from families in which at least one parent had to work remotely continued to show lower HRQOL in January and March 2021. Conclusion: Changes in parents' working conditions during lockdown were negatively associated with children's HRQOL. Public health policies aiming to support families susceptible to adverse changes are needed.

COVID-19 , Calidad de Vida , COVID-19/epidemiología , Niño , Control de Enfermedades Transmisibles , Estudios Transversales , Humanos , Pandemias , Padres , Estudios Prospectivos
Int J Public Health ; 67: 1604474, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36090839


Objective: Studies from the past decades have shown that mood disorders are common during childhood and adolescence. This study aimed to estimate the point prevalence of depression in Omani children and adolescents during social distancing and lockdown and identify the risk factors for developing depressive symptoms during the COVID-19 pandemic. Methods: This is an analytical cross-sectional study conducted in May 2020, in which all young Omani people attending a mainstream school aged 8-18 years old were eligible to participate. Parents were asked to complete the online survey, which consisted of the parent version of the Mood and Feelings Questionnaire (MFQ-Parent). In addition, the option of a self-reported version (MFQ-Self) was provided in cases where children preferred to fill out the survey themselves. Logistic regression was used to identify the contributing socio-demographic variables associated with depressive symptoms. Results: A total of 445 participants completed the MFQ, out of which 72.1% were parents, and 27.9% were children, adolescents and young people. 13.9% of children and adolescents exhibited depressive symptoms during the COVID-19 pandemic in Oman. The presence of depressive symptoms was associated with increased food intake (OR 1.81, 95% CI 1.00-3.29, p-value <0.05), longer use of smartphones (OR 2.72, 95% CI 1.56-4.73, p-value <0.001), whereas additional entertainment activities during lockdown were protective against depression (OR 0.35 95% CI 0.19-0.64, p-value <0.001). Conclusion: This study from Oman concurs with recent reports of depression being common during the COVID-19 pandemic. Concerted efforts are needed to mitigate this trend and identify high-risk groups during the lockdown period.

COVID-19 , Depresión , Adolescente , COVID-19/epidemiología , Niño , Control de Enfermedades Transmisibles , Estudios Transversales , Depresión/epidemiología , Humanos , Omán/epidemiología , Pandemias , Padres , Prevalencia
Int J Public Health ; 67: 1604591, 2022.
Artículo en Inglés | MEDLINE | ID: mdl-36090842


Objective: We examine the impact of financial distress caused by the COVID-19 pandemic on mental health and psychological well-being. Methods: We analyze cross-sectional survey data (n = 2,545) from the Life during Pandemic study in Chile. We estimate linear probability models to analyze the relationship between economic fragility, financial distress, and psychological well-being. Results: Our findings show unemployment and income loss are highly predictive of experiencing a range of financial problems, such as a lack of savings, as well as difficulties paying bills, consumer debt, and mortgage loans. In turn, financial distress leads to a higher prevalence of poor well-being and mental health deterioration, and sleep problems. Conclusion: Expansion of mental health assistance services are needed, as new diagnosis of mental health conditions has increased, but treatment has not, pointing to a barrier in the access to some mental health care services during the pandemic. Policies designed with the objective of improving financial education are necessary to increase precautionary savings and financial resilience, and alleviate the psychological burden of debt in the future.

COVID-19 , COVID-19/epidemiología , Estudios Transversales , Humanos , Salud Mental , Pandemias , Estrés Psicológico/epidemiología , Estrés Psicológico/psicología