Evaluation of proactive therapeutic drug monitoring application in infliximab users in ulcerative colitis
J. coloproctol. (Rio J., Impr.)
; 43(4): 286-291, Oct.-Dec. 2023. tab
Article
en En
| LILACS
| ID: biblio-1528937
Biblioteca responsable:
BR545.3
ABSTRACT
Objective:
To evaluate the application of proactive pro-drug therapy (TDM) at week six in users of infliximab therapy in ulcerative colitis patients and to analyze the need for further disease optimization.Method:
This is a retrospective analysis that will be carried out simultaneously at the Hospital de Clínicas de Passo Fundo and at the Endoclin Diagnostic Center in the city of Passo Fundo, with secondary data collection between January 2020 and May 2022. The sample included patients from both sexes, regardless of age, who are being followed up in the services mentioned above, by signing the informed Free and Clarified Consent Term.Results:
63.2% of patients required optimization of their treatment based on the serum level assessment at week six.Conclusion:
Proactive TDM performed at week six benefits patients in order to complete indications for treatment to avoid lack of drug response and complications from the disease. (AU)Palabras clave
Texto completo:
1
Base de datos:
LILACS
Asunto principal:
Colitis Ulcerosa
/
Monitoreo de Drogas
Idioma:
En
Revista:
J. coloproctol. (Rio J., Impr.)
Asunto de la revista:
Cirurgia
/
Doenas Retais
/
Doenas do Colo
/
GASTROENTEROLOGIA
/
Cirurgia
Año:
2023
Tipo del documento:
Article