Heart specific expression of mouse BMP-10 a novel member of the TGF-beta superfamily.
Mech Dev
; 80(2): 181-4, 1999 Feb.
Article
en En
| MEDLINE
| ID: mdl-10072785
ABSTRACT
Here we report the cloning and expression of murine BMP-10, a novel member of the TGF-beta superfamily. In the mouse embryo, BMP-10 expression begins at 9.0 d.p.c. and is restricted to the developing heart. Initially, BMP-10 expression localizes to the trabeculated part of the common ventricular chamber and to the bulbus cordis region. After 12.5 d.p.c., additional BMP-10 expression is seen in the atrial wall. The data presented here suggest that BMP-10 plays an important role in trabeculation of the embryonic heart.
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Base de datos:
MEDLINE
Asunto principal:
Familia de Multigenes
/
Regulación del Desarrollo de la Expresión Génica
/
Proteínas Morfogenéticas Óseas
/
Corazón Fetal
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Proteínas Fetales
/
Genes
/
Proteínas Musculares
/
Miocardio
Idioma:
En
Revista:
Mech Dev
Asunto de la revista:
EMBRIOLOGIA
Año:
1999
Tipo del documento:
Article