[Serum soluble interleukin-2 receptor in patients with pulmonary mycobacterial diseases].
Kekkaku
; 74(6): 499-505, 1999 Jun.
Article
en Ja
| MEDLINE
| ID: mdl-10423961
ABSTRACT
Serum soluble interleukin-2 receptor (sIL-2R) levels were measured in patients with untreated pulmonary tuberculosis (24 cases), patients with multidrug-resistant intractable pulmonary tuberculosis (7 cases) and patients with pulmonary non-tuberculous mycobacteriosis (27 cases). Serum sIL-2R levels were elevated in patients with pulmonary mycobacterial diseases and were elevated in untreated pulmonary tuberculosis patients than in other patients. In patients with new tuberculosis, serum sIL-2R levels were higher in patients with extensive lesions. Serum sIL-2R level showed significant positive correlation with serum C-reactive protein level and erythrocyte sedimentation rate, and significant negative correlation with serum albumin level. In patients with intractable tuberculosis and patients with non-tuberculous mycobacteriosis, serum sIL-2R levels were lower than in patients with new tuberculosis. Even in patients with extensive lesions, serum sIL-2R levels were not elevated. Lower levels of serum sIL-2R, marker of immunocompetent cell activity, suggested that immunocompetent cell activity was suppressed in intractable tuberculosis and in non-tuberculous mycobacteriosis.
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Base de datos:
MEDLINE
Asunto principal:
Tuberculosis Pulmonar
/
Receptores de Interleucina-2
Idioma:
Ja
Revista:
Kekkaku
Año:
1999
Tipo del documento:
Article