First year after head and neck cancer: quality of life.
J Clin Oncol
; 17(1): 352-60, 1999 Jan.
Article
en En
| MEDLINE
| ID: mdl-10458254
ABSTRACT
PURPOSE:
Treatment regimens for head and neck cancer patients profoundly affect several quality-of-life domains. Rehabilitative needs have been identified through cross-sectional analyses; however, few studies have prospectively assessed quality of life, included assessment of psychosocial variables, and identified predictors of long-term follow-up. PARTICIPANTS ANDMETHODS:
The present study addresses these limitations through a prospective assessment of 105 patients with a newly diagnosed first primary squamous cell carcinoma of the oral cavity, pharynx, or larynx. Participants were enrolled onto a larger randomized controlled trial comparing a provider-delivered smoking cessation intervention with a usual-care-advice control condition. Participants completed a battery of self-report measures after diagnosis and before treatment and additional quality-of-life instruments at 1 and 12 months after initial smoking cessation advice.RESULTS:
Participants displayed improvements at 12 months in functional status (P = .006) and in the areas of eating, diet, and speech; however, the latter three represent areas of continued dysfunction, and the changes were not statistically significant. Despite these improvements, patients reported a decline in certain quality-of-life domains, including marital (P = .002) and sexual functioning (P = .017), as well as an increase in alcohol use (P < .001). Predictors of quality of life at 12 months included treatment type, the Vigor subscale of the Profile of Mood States instrument, and quality-of-life scores obtained 1 month after initial smoking cessation advice.CONCLUSION:
Results reinforce the need for rehabilitation management through the integration of psychologic and behavioral interventions in medical follow-up.
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Base de datos:
MEDLINE
Asunto principal:
Calidad de Vida
/
Carcinoma de Células Escamosas
/
Neoplasias de Cabeza y Cuello
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Prognostic_studies
Idioma:
En
Revista:
J Clin Oncol
Año:
1999
Tipo del documento:
Article