Demonstration of glycosaminoglycans in Caenorhabditis elegans.
FEBS Lett
; 459(3): 327-31, 1999 Oct 15.
Article
en En
| MEDLINE
| ID: mdl-10526159
ABSTRACT
A considerable amount (approximately 1.6 microg from 1 mg of dried nematode) of non-sulfated chondroitin, two orders of magnitude less yet an appreciable amount of heparan sulfate, and no hyaluronate were found in Caenorhabditis elegans nematodes. The chondroitin chains were heterogeneous in size, being shorter than that of whale cartilage chondroitin sulfate. The disaccharide composition analysis of heparan sulfate revealed diverse sulfation including glucosamine 2-N-sulfation, glucosamine 6-O-sulfation and uronate 2-O-sulfation. These results imply that chondroitin and heparan sulfate are involved in fundamental biological processes.
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Base de datos:
MEDLINE
Asunto principal:
Caenorhabditis elegans
/
Glicosaminoglicanos
Idioma:
En
Revista:
FEBS Lett
Año:
1999
Tipo del documento:
Article