Low grade fibromyxoid sarcoma. a further low-grade soft tissue malignancy characterized by a ring chromosome.
Cancer Genet Cytogenet
; 122(2): 144-8, 2000 Oct 15.
Article
en En
| MEDLINE
| ID: mdl-11106828
ABSTRACT
Supernumerary rings in the context of a simple karyotype characterize several low-grade malignant tumors of soft tissue and bone. Low-grade fibromyxoid sarcoma is an uncommon low-grade sarcoma, the cytogenetics of which has not yet been reported. Here we describe the first molecular-cytogenetic characterization of a pulmonary metastasis of low-grade fibromyxoid sarcoma. The histology of the primary and recurrent tumors was consistent with the diagnosis of low-grade fibromyxoid sarcoma of the usual type, whereas the pulmonary metastasis was of the "giant rosettes" variant. Cytogenetic analysis revealed a ring chromosome. Because gain of material of chromosomes 7 and 16 was detected by CGH, the ring chromosome is assumed to be composed of material from these respective chromosomes.
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Base de datos:
MEDLINE
Asunto principal:
Cromosomas en Anillo
/
Neoplasias de los Tejidos Blandos
/
Fibrosarcoma
Idioma:
En
Revista:
Cancer Genet Cytogenet
Año:
2000
Tipo del documento:
Article