Treatment of sepsis in cardiac surgery: role of immunoglobulins.
Perfusion
; 16(2): 113-20, 2001 Mar.
Article
en En
| MEDLINE
| ID: mdl-11334194
ABSTRACT
Cardiopulmonary bypass (CPB) is associated with an injury that may cause pathophysiological changes such as systemic inflammatory response syndrome, multiple organ dysfunction syndrome, and mediator-induced multiorgan failure. Systemic endotoxinaemia, release of proinflammatory cytokines, and interactions between neutrophils and endothelium have been reported to correlate with a high incidence of organ dysfunction, infection and sepsis following cardiac surgery. This review discusses the dysregulation of the immune response as a major reason for the higher susceptibility to infections following cardiac surgery, various treatment strategies to reduce CPB-induced inflammation, and especially the prophylactic use of immunoglobulins in cardiac surgery.
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Base de datos:
MEDLINE
Asunto principal:
Puente Cardiopulmonar
/
Sepsis
Tipo de estudio:
Etiology_studies
Idioma:
En
Revista:
Perfusion
Asunto de la revista:
CARDIOLOGIA
Año:
2001
Tipo del documento:
Article