Regulation and function of the p53 tumor suppressor protein.
Curr Opin Cell Biol
; 13(3): 332-7, 2001 Jun.
Article
en En
| MEDLINE
| ID: mdl-11343904
ABSTRACT
Loss of the p53 tumor suppressor pathway contributes to the development of most human cancers. p53 is a nuclear protein that functions as a regulator of transcription. Significant advances have been made recently in our understanding of how p53 function is regulated and the mechanisms by which p53 mediates its effects.
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Base de datos:
MEDLINE
Asunto principal:
Transcripción Genética
/
Compartimento Celular
/
Proteína p53 Supresora de Tumor
/
Apoptosis
/
Neoplasias
Idioma:
En
Revista:
Curr Opin Cell Biol
Año:
2001
Tipo del documento:
Article