Reduced developmental potential in oocytes from women with endometriosis.
J Assist Reprod Genet
; 18(12): 644-9, 2001 Dec.
Article
en En
| MEDLINE
| ID: mdl-11808845
ABSTRACT
PURPOSE:
To study retrospectively the outcome of intracytoplasmatic sperm injection (ICSI) in women with endometriosis compared with women with no known female infertility factor.METHODS:
All couples treated with ICSI because of male infertility plus verified endometriosis (n = 26) and all couples treated with ICSI because of male infertility only (n = 125) during the period January 1995 to June 1999 were included. Data were collected from patient files and ICSI protocols.RESULTS:
The time to complete down regulation was significantly longer (p = 0.0108), the dose of FSH significantly higher (0.0247), the day for oocyte pickup significantly later (p = 0.0091), and the cleavage rate of oocytes significantly lower (p = 0.0011) in women with endometriosis compared with controls. There was no significant difference in implantation rate or pregnancy rate between the groups.CONCLUSIONS:
Women with endometriosis presented significantly reduced follicular response and oocyte cleavage rate, two mechanisms that might be related to a disturbed oogenesis.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Oocitos
/
Resultado del Embarazo
/
Fertilización In Vitro
/
Inyecciones de Esperma Intracitoplasmáticas
/
Endometriosis
Idioma:
En
Revista:
J Assist Reprod Genet
Asunto de la revista:
GENETICA
/
MEDICINA REPRODUTIVA
Año:
2001
Tipo del documento:
Article