Association of parvovirus B19 infection with acute glomerulonephritis in healthy adults: case report and review of the literature.
Clin Nephrol
; 57(1): 69-73, 2002 Jan.
Article
en En
| MEDLINE
| ID: mdl-11837804
ABSTRACT
An otherwise healthy 20-year-old woman presented with an erythematous rash on her face as well as arthralgia and anemia. She also had systemic edema, proteinuria and hypertension. Laboratory data on admission showed hypocomplementemia, human parvovirus B 19 (HPV) DNA and both immunoglobulin (Ig) M and IgG antibodies to HPV in her serum. Renal biopsy specimens showed features of endocapillary glomerulonephritis under light microscopy. Electron microscopy showed massive subendothelial electron-dense deposits. No cause was probable other than immune complex-mediated glomerulonephritis associated with HPV infection. In a review of this and similar cases reported in the literature, several characteristic features come to light female dominance, onset in the second or third decade of life, hypocomplementemia, histologic renal endocapillary and/or mesangioproliferative glomerulonephritis with subendothelial deposits and spontaneous recovery.
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Base de datos:
MEDLINE
Asunto principal:
Parvovirus B19 Humano
/
Infecciones por Parvoviridae
/
Glomerulonefritis
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Idioma:
En
Revista:
Clin Nephrol
Año:
2002
Tipo del documento:
Article