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Synthesis of the kappa-agonist CJ-15,161 via a palladium-catalyzed cross-coupling reaction.
Ghosh, Arun; Sieser, Janice E; Caron, Stéphane; Watson, Timothy J N.
Afiliación
  • Ghosh A; Chemical Research and Development, Pfizer Global Research and Development, Eastern Point Road, P.O. Box 8013, Groton, CT 06340-8013, USA. Arun_Ghosh@groton.pfizer.com
Chem Commun (Camb) ; (15): 1644-5, 2002 Aug 07.
Article en En | MEDLINE | ID: mdl-12170823
ABSTRACT
Syntheses of CJ-15,161 (1) involving intermolecular N-arylation of an appropriately functionalized diamine, obtained from the precursor alpha-amino acids or, more conveniently, from the corresponding 1,2-amino alcohols via 1,2,3-oxathiazolidine-2,2-dioxide 22, are reported.
Asunto(s)
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Base de datos: MEDLINE Asunto principal: Receptores Opioides kappa Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2002 Tipo del documento: Article
Buscar en Google
Base de datos: MEDLINE Asunto principal: Receptores Opioides kappa Idioma: En Revista: Chem Commun (Camb) Asunto de la revista: QUIMICA Año: 2002 Tipo del documento: Article