The cardioprotective role of beta-blockers in patients with diabetes mellitus.
J Clin Pharm Ther
; 27(4): 233-42, 2002 Aug.
Article
en En
| MEDLINE
| ID: mdl-12174024
ABSTRACT
This paper reviews the role of beta-blockers in the prevention of cardiovascular morbidity and mortality in patients with diabetes mellitus. There is good evidence from randomized controlled trials that beta-blockers, in particular the lipophilic agents, substantially reduce cardiovascular mortality and morbidity. However, hitherto beta-blockers have been underused in diabetic patients, perhaps because of perceived risks of beta-blocker therapy. Reappraisal of the evidence suggests that the traditional reluctance to use beta-blockers in this group is based on fears of adverse effects that are largely unfounded.
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Base de datos:
MEDLINE
Asunto principal:
Antagonistas Adrenérgicos beta
/
Enfermedad Coronaria
/
Complicaciones de la Diabetes
Tipo de estudio:
Clinical_trials
/
Observational_studies
/
Risk_factors_studies
Idioma:
En
Revista:
J Clin Pharm Ther
Asunto de la revista:
FARMACIA
/
TERAPEUTICA
Año:
2002
Tipo del documento:
Article