[Treatment of second primary malignant tumor induced by radiotherapy].
Zhonghua Zhong Liu Za Zhi
; 25(3): 275-7, 2003 May.
Article
en Zh
| MEDLINE
| ID: mdl-12839694
ABSTRACT
OBJECTIVE:
To study the diagnosis and treatment of a second primary malignant tumor induced by previous radiotherapy.METHODS:
From March 1970 to March 1997, 108 nasopharyngeal cancer (NPC) patients who developed a second primary malignant tumor induced by radiotherapy were treated. There were squamous carcinoma 43 (39.8%), sarcoma 26 (24.1%), malignant fibrous histiocytoma 14 (13.0%), adenoid cystic carcinoma 12 (11.1%), thyroid papillary adenocarcinoma 8 (7.4%) and malignant melanoma 5 (4.6%). Fifty patients underwent operation, 32 received radiotherapy, 18 received chemotherapy and 8 received operation combined with chemotherapy.RESULTS:
The 3- and 5-year tumor-free survival rates were 64.0% and 36.0% in the operation group. They were 34.4% and 18.8% in the radiotherapy group.CONCLUSION:
Surgery, if not contra-indicated, is the first choice for the second primary malignant tumor induced by radiotherapy. Aggressive treatment for these patients is, hence, indicated clinically.
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Base de datos:
MEDLINE
Asunto principal:
Radioterapia
/
Neoplasias Primarias Secundarias
/
Neoplasias Inducidas por Radiación
Tipo de estudio:
Diagnostic_studies
Idioma:
Zh
Revista:
Zhonghua Zhong Liu Za Zhi
Año:
2003
Tipo del documento:
Article