Diastereo- and enantioselective synthesis of 1'-C-branched N,O-nucleosides.
Nucleosides Nucleotides Nucleic Acids
; 22(5-8): 739-42, 2003.
Article
en En
| MEDLINE
| ID: mdl-14565267
ABSTRACT
A synthetic approach towards 1'-C-branched N,O-nucleosides is reported, based on 1,3-dipolar cycloaddition of ethoxycarbonylnitrone. The asymmetric version of the process exploits the presence of a chiral auxiliary at the carbon atom of nitrone and leads to beta-D and beta-L nucleosides in good yields.
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Base de datos:
MEDLINE
Asunto principal:
Óxidos de Nitrógeno
/
Nucleósidos
Idioma:
En
Revista:
Nucleosides Nucleotides Nucleic Acids
Asunto de la revista:
BIOQUIMICA
Año:
2003
Tipo del documento:
Article