Model-based parameter estimation using cardiovascular response to orthostatic stress.
Comput Cardiol
; 28: 337-40, 2001.
Article
en En
| MEDLINE
| ID: mdl-14640093
This paper presents a cardiovascular model that is capable of simulating the short-term (< or approximately equal to 3 min) transient hemodynamic response to gravitational stress and a gradient-based optimization method that allows for the automated estimation of model parameters from simulated or experimental data. We perform a sensitivity analysis of the transient heart rate response to determine which parameters of the model impact the heart rate dynamics significantly. We subsequently include only those parameters in the estimation routine that impact the transient heart rate dynamics substantially. We apply the estimation algorithm to both simulated and real data and showed that restriction to the 20 most important parameters does not impair our ability to match the data.
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Base de datos:
MEDLINE
Asunto principal:
Simulación por Computador
/
Gravitación
/
Frecuencia Cardíaca
/
Hemodinámica
/
Hipotensión Ortostática
/
Modelos Cardiovasculares
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
Comput Cardiol
Año:
2001
Tipo del documento:
Article