[Delayed onset of malignant hyperthermia crisis during a living donor liver transplantation caused by sevoflurane]. / Verzögertes Einsetzen einer Malignen Hyperthermie während einer Leberlebendspende unter Sevoflurananästhesie.
Anasthesiol Intensivmed Notfallmed Schmerzther
; 39(3): 153-6, 2004 Mar.
Article
en De
| MEDLINE
| ID: mdl-15042505
ABSTRACT
We report on a 25-year old ASA physical status I patient, who developed within 20 minutes a full-blown malignant hyperthermia (MH) in the context of a living donor liver transplantation after 180 minutes of uneventful anaesthesia. The only trigger substance applied was Sevoflurane. The patient had already received a short, uneventful anaesthesia with Isoflurane a couple of years ago. In the context of the special constellation an initial dose of Dantrolene of 10 mg/kg body weight was administered. The patient was stabilised within 30 minutes, and the enzyme levels remained low compared with other case reports. The post-operative in vitro caffeine halothane contracture testing confirmed that son and mother were susceptible to MH, contracture testing in the father was negative. All known triggers may cause life-threatening MH crisis - even after hours and after inconspicuous multiple exposures to known trigger substances. Therefore all trigger substances must be avoided in all patients susceptible to MH.
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Base de datos:
MEDLINE
Asunto principal:
Trasplante de Hígado
/
Anestésicos por Inhalación
/
Donadores Vivos
/
Anestesia por Inhalación
/
Hipertermia Maligna
/
Éteres Metílicos
Idioma:
De
Revista:
Anasthesiol Intensivmed Notfallmed Schmerzther
Asunto de la revista:
ANESTESIOLOGIA
/
MEDICINA DE EMERGENCIA
/
TERAPIA INTENSIVA
Año:
2004
Tipo del documento:
Article