Prevalence of human papillomavirus infection and correlation with cervical lesions in Japanese women.
J Obstet Gynaecol Res
; 30(5): 380-5, 2004 Oct.
Article
en En
| MEDLINE
| ID: mdl-15327453
ABSTRACT
PURPOSE:
To investigate the prevalence of human papillomavirus (HPV) infection in patients attending a gynecologic outpatient department, and to correlate the infection status with the presence or absence of uterine cervical lesions and the grades assessed by cytological or histological examinations.METHODS:
Five hundred and seventy-two subjects were studied. In all subjects, HPV detection by the hybrid capture method and a cervical cytological examination were performedRESULTS:
The HPV-positive rate in subjects with normal cytology was 12.3%. The detection rate was high (21.7%) in subjects aged in the twenties and low in the forties, and HPV was not detected in subjects aged in the sixties and seventies. When HPV-positive rates were examined according to cytological or histological grades, the rates were higher in subjects with abnormal cytology (P < 0.01) or cervical intraepithelial neoplasia (CIN) or squamous cell carcinoma compared with those with normal cytology.CONCLUSION:
Diagnosis of HPV infection is also important for the prediction of progression to CIN and cervical cancer.
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Base de datos:
MEDLINE
Asunto principal:
Papillomaviridae
/
Enfermedades del Cuello del Útero
/
Infecciones por Papillomavirus
Tipo de estudio:
Prevalence_studies
/
Risk_factors_studies
Idioma:
En
Revista:
J Obstet Gynaecol Res
Asunto de la revista:
GINECOLOGIA
/
OBSTETRICIA
Año:
2004
Tipo del documento:
Article