Cys-tRNACys formation and cysteine biosynthesis in methanogenic archaea: two faces of the same problem?
Cell Mol Life Sci
; 61(19-20): 2437-45, 2004 Oct.
Article
en En
| MEDLINE
| ID: mdl-15526152
ABSTRACT
Aminoacyl-tRNA (transfer RNA) synthetases are essential components of the cellular translation machinery as they provide the ribosome with aminoacyl-tRNAs. Aminoacyl-tRNA synthesis is generally well understood. However, the mechanism of Cys-tRNACys formation in three methanogenic archaea ( Methanocaldococcus jannaschii, Methanothermobacter thermautotrophicus and Methanopyrus kandleri) is still unknown, since no recognizable gene for a canonical cysteinyl-tRNA synthetase could be identified in the genome sequences of these organisms. Here we review the different routes recently proposed for Cys-tRNACys formation and discuss its possible link with cysteine biosynthesis in these methanogenic archaea.
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Base de datos:
MEDLINE
Asunto principal:
Aminoacil-ARN de Transferencia
/
Archaea
/
Genes Arqueales
/
Cisteína
Idioma:
En
Revista:
Cell Mol Life Sci
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2004
Tipo del documento:
Article