Efforts toward oral bioavailability in factor VIIa inhibitors.
Bioorg Med Chem Lett
; 16(14): 3829-32, 2006 Jul 15.
Article
en En
| MEDLINE
| ID: mdl-16650987
ABSTRACT
Efforts toward developing orally bioavailable factor VIIa inhibitors starting from parenteral lead compound 1 are described. SAR resulted in improved physicochemical properties, leading to enhanced oral absorption in rat.
Buscar en Google
Base de datos:
MEDLINE
Asunto principal:
Trombosis
/
Factor VIIa
/
Anticoagulantes
Idioma:
En
Revista:
Bioorg Med Chem Lett
Asunto de la revista:
BIOQUIMICA
/
QUIMICA
Año:
2006
Tipo del documento:
Article