A strongly basic protein of the MAP2 family copolymerizes with tubulin and induces polymerization.
J Protein Chem
; 10(5): 511-6, 1991 Oct.
Article
en En
| MEDLINE
| ID: mdl-1799409
The family of microtubuli-associated proteins of approximately 300 kD molecular weight (MAP2) from porcine brain was fractionated into components of neutral isoelectric point and one polypeptide of strongly basic nature. Both fractions are able to induce the polymerization of purified porcine brain tubulin. In the case of the fractions of an isoelectric point of 7.2, thick and short tubular structures result. Under the influence of the basic protein, extremely long tubules of normal diameter of microtubules are produced. This basic MAP2 copolymerizes with tubulin.
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Base de datos:
MEDLINE
Asunto principal:
Polímeros
/
Tubulina (Proteína)
/
Química Encefálica
/
Proteínas Asociadas a Microtúbulos
Idioma:
En
Revista:
J Protein Chem
Año:
1991
Tipo del documento:
Article