Polymethoxylated flavones metabolites in rat plasma after the consumption of Fructus aurantii extract: analysis by liquid chromatography/electrospray ion trap mass spectrometry.
J Pharm Biomed Anal
; 46(3): 543-9, 2008 Feb 13.
Article
en En
| MEDLINE
| ID: mdl-18164892
ABSTRACT
A LC with full scan MS(n) method was developed in order to investigate the in vivo absorption and biotransformation of polymethoxylated flavones (PMFs) by analysis of plasma samples from rats after ingestion of Fructus aurantii extract. Four parent compounds and six metabolites with intact flavonoid structures were tentatively identified. The metabolites were either glucuronides of parent compounds or glucuronides of demethylated products of parent compounds.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Extractos Vegetales
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Cromatografía Liquida
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Citrus
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Espectrometría de Masa por Ionización de Electrospray
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Flavanonas
Idioma:
En
Revista:
J Pharm Biomed Anal
Año:
2008
Tipo del documento:
Article