Immunological and clinical aspects of lymphocytic hypophysitis.
Clin Sci (Lond)
; 114(6): 413-21, 2008 Mar.
Article
en En
| MEDLINE
| ID: mdl-18260829
ABSTRACT
LYH (lymphocytic hypophysitis) is an autoimmune disease of the pituitary gland which can present with varying degrees of pituitary hormonal impairment and/or with symptoms related to pituitary enlargement. In this review, we provide an overview of the epidemiology, diagnosis, pathogenesis, treatment, and the role of organ-specific and antipituitary antibodies as potential markers of LYH. In addition, although the mechanisms underlying LYH are not completely understood, the role of prolactin, which plays an important part in maintaining immune system homoeostasis and is increased in the disease, is considered.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Enfermedades de la Hipófisis
/
Enfermedades Autoinmunes
/
Linfocitosis
Tipo de estudio:
Etiology_studies
Idioma:
En
Revista:
Clin Sci (Lond)
Año:
2008
Tipo del documento:
Article