New approaches to the treatment of human herpesvirus 8-associated disease.
Rev Med Virol
; 18(5): 321-9, 2008.
Article
en En
| MEDLINE
| ID: mdl-18615774
ABSTRACT
Human herpesvirus 8 (HHV-8, also known as Kaposi sarcoma-associated herpesvirus or KSHV) is the etiologic agent of Kaposi sarcoma (KS) and primary effusion lymphoma (PEL), as well as many cases of Castleman disease. Despite significant advances in understanding the biology and natural history of these diseases, current treatment options have important limitations, and strategies to prevent their development in high-risk individuals are lacking. This article reviews the scope of HHV-8-associated disease, as well as the efficacy of current treatment options. Finally, novel approaches to treatment and prevention are described, including antiviral agents, targeted molecular therapy and a combination of these modalities.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Infecciones por Herpesviridae
/
Herpesvirus Humano 8
Tipo de estudio:
Risk_factors_studies
Idioma:
En
Revista:
Rev Med Virol
Asunto de la revista:
VIROLOGIA
Año:
2008
Tipo del documento:
Article