[Multiple skin cancers in a patient treated with hydroxyurea]. / Multiple kutane Neoplasien nach Therapie mit Hydroxyurea.
Hautarzt
; 60(8): 651-2, 654, 2009 Aug.
Article
en De
| MEDLINE
| ID: mdl-19096810
ABSTRACT
A 62-year-old patient treated for 9 years with hydroxyurea for chronic myeloproliferative disease developed multiple cutaneous neoplasms. Hydroxyurea minimizes DNA synthesis via inhibition of the enzyme ribonucleotide reductase and is used to treat hematological malignancies. The most important and severe side-effect is a dose-dependent myelodepression. An association with multiple skin tumors has been reported. The presented case emphasizes this potential risk of hydroxyurea therapy. Continuous dermatologic monitoring of patients treated with hydroxyurea is recommended.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Neoplasias Cutáneas
/
Hidroxiurea
/
Neoplasias Primarias Múltiples
Idioma:
De
Revista:
Hautarzt
Año:
2009
Tipo del documento:
Article