Cardiac angioleiomyoma in 44 cattle in Japan (1982-2009).
Vet Pathol
; 47(5): 923-30, 2010 Sep.
Article
en En
| MEDLINE
| ID: mdl-20574072
ABSTRACT
A retrospective study was performed on primary cardiac tumors found in 44 cattle during meat inspection in Japan, using histology, immunohistochemistry, and electron microscopy. The age of affected cattle ranged from 10 to 129 months; 82% were less than 3 years old. In 38 hearts, the tumor was solitary; the remaining 6 hearts had multiple masses. All tumors were subendocardial and involved the papillary muscles and/or cardiac valves. Two histologic patterns were recognized; both included giant cells. Pattern 1 was characterized by interlacing fascicles of spindle-shaped cells; pattern 2 resembled cavernous hemangioma. The 2 patterns coexisted and were linked by transitional zones. Given the immunohistochemical reactivity and ultrastructure, the spindle-shaped cells were identified as smooth muscle cells and the giant cells as endothelial cells. Single cell and multicellular angiogenesis by giant cells was observed. The tumors were classified as cardiac angioleiomyoma. Subendocardial multipotential mesenchymal cells, persistent tissue of the endocardial cushion, or valvular interstitial cells were suspected as the origin.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Enfermedades de los Bovinos
/
Angiomioma
/
Neoplasias Cardíacas
Tipo de estudio:
Observational_studies
Idioma:
En
Revista:
Vet Pathol
Año:
2010
Tipo del documento:
Article