High prevalence of ST121 in community-associated methicillin-susceptible Staphylococcus aureus lineages responsible for skin and soft tissue infections in Portuguese children.
Eur J Clin Microbiol Infect Dis
; 30(2): 293-7, 2011 Feb.
Article
en En
| MEDLINE
| ID: mdl-21046422
ABSTRACT
In order to evaluate the incidence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) in Portugal, we analyzed a collection of 38 S. aureus isolates recovered from 30 children attending the pediatric emergency department of a central hospital in Lisbon due to skin and soft tissue infections. Molecular characterization identified seven clonal lineages among the 35 methicillin-susceptible S. aureus (MSSA) isolates, of which the major lineage PFGE A/t159/ST121 included 63% of the isolates. The three MRSA isolates belonged to the Pediatric clone PFGE D/t535/ST5-IV (n = 2) and to the European CA-MRSA clone PFGE G/t044/ST80-IVc (n = 1). All isolates harbored several virulence factors, namely, leukocidins. Panton-Valentine leukocidin (PVL) was produced by isolates from five MSSA lineages and by the ST80 MRSA. Of interest, this is the first reported isolation of CA-MRSA ST80 in Portugal.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Staphylococcus aureus
/
Infecciones Cutáneas Estafilocócicas
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Técnicas de Tipificación Bacteriana
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Infecciones Comunitarias Adquiridas
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Infecciones de los Tejidos Blandos
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Tipificación Molecular
Tipo de estudio:
Prevalence_studies
/
Prognostic_studies
País/Región como asunto:
Europa
Idioma:
En
Revista:
Eur J Clin Microbiol Infect Dis
Asunto de la revista:
DOENCAS TRANSMISSIVEIS
/
MICROBIOLOGIA
Año:
2011
Tipo del documento:
Article