Diffusion-weighted MRI with parallel imaging technique: apparent diffusion coefficient determination in normal kidneys and in nonmalignant renal diseases.
Clin Imaging
; 34(6): 432-40, 2010.
Article
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| MEDLINE
| ID: mdl-21092872
ABSTRACT
The purpose of the study was to assess the capability and the reliability of apparent diffusion coefficient (ADC) measurements in the evaluation of different benign renal abnormalities. Twenty-five healthy volunteers and 31 patients, divided into seven different groups (A-G) according to pathology, underwent diffusion-weighted magnetic resonance imaging (DW MRI) of the kidneys using 1.5-T system. DW images were obtained in the axial plane with a spin-echo echo planar imaging single-shot sequence with three b values (0, 300, and 600 s/mm²). Before acquisition of DW sequences, we performed in each patient a morphological study of the kidneys. ADC was 2.40±0.20×10⻳ mm² s⻹ in volunteers. A significant difference was found between Groups A (cysts=3.39±0.51×10⻳ mm² s⻹) and B (acute/chronic renal failure=1.38±0.40×10⻳ mm² s⻹) and between Groups A and C (chronic pyelonephritis=1.53±0.21×10⻳ mm² s⻹) (P<.05). An important difference was also observed among Group D (hydronephrosis=4.82±0.35×10⻳ mm² s⻹) and Groups A, B, and C (P<.05), whereas no differences were found between Groups B and C (P>.05). A considerable correlation between glomerular filtration rate and ADC was found (P=.04). In conclusion, significant differences were detected among different patient groups, and this suggests that ADC measurements can be useful in differentiating normal renal parenchyma from most commonly encountered nonmalignant renal lesions.
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1
Base de datos:
MEDLINE
Asunto principal:
Algoritmos
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Interpretación de Imagen Asistida por Computador
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Aumento de la Imagen
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Imagen de Difusión por Resonancia Magnética
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Riñón
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Enfermedades Renales
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
Clin Imaging
Asunto de la revista:
DIAGNOSTICO POR IMAGEM
Año:
2010
Tipo del documento:
Article