Adherence to diet and quality of life in patients with phenylketonuria.
Acta Paediatr
; 100(8): 1144-9, 2011 Aug.
Article
en En
| MEDLINE
| ID: mdl-21342250
ABSTRACT
AIM:
To investigate adherence to dietary treatment and quality of life (QoL) in patients with phenylketonuria (PKU).METHODS:
In the setting of a tertiary paediatric hospital, 41 early-treated patients affected by PKU aged more than 3 years old were enrolled in a cross-sectional study. Three-days dietary assessment, QoL questionnaires for patients<18 years old (Child Health Questionnaire) and Short Form for adults were completed.RESULTS:
Of 41 patients, 23 (56.1%) were considered adherent to the dietary prescriptions as their phenylalanine intake was less than prescribed. Phenylalanine intake was significantly in excess of prescribed if mothers had a lower level of education. Adherence was not correlated with age. Metabolic control was obtained in 41.5-51.2% of the patients depending on the target. QoL was reduced in children and adolescents. There was no significant correlation between adherence and QoL, except for the domains of Global Health and Family Activities (ρ=0.42 and 0.46, respectively). The overall agreement between adherence and metabolic control varied according to different targets of metabolic control (51.2-65.9%).CONCLUSIONS:
It is necessary to improve the adherence to diet and the QoL in children and adolescents affected by PKU.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Fenilcetonurias
/
Calidad de Vida
/
Cooperación del Paciente
Tipo de estudio:
Observational_studies
Idioma:
En
Revista:
Acta Paediatr
Año:
2011
Tipo del documento:
Article