Value of 18-FDG-positron emission tomography/computed tomography before and after transarterial chemoembolization in patients with hepatocellular carcinoma undergoing liver transplantation: initial results.
Transplant Proc
; 43(6): 2213-5, 2011.
Article
en En
| MEDLINE
| ID: mdl-21839236
ABSTRACT
INTRODUCTION:
Liver transplantation is the treatment of choice for various types of end-stage liver disease and the most appropriate alternative for the treatment of hepatocellular carcinoma (HCC)-associated liver cirrhosis. The aim of this study was to describe our initial experience with the use of 18-FDG positron emission tomography (PET)/computed tomography CT before and after transarterial chemoembolization (TACE) in HCC patients undergoing liver transplantation, seeking to predict the percentage of tumor necrosis achieved by TACE procedures. PATIENTS ANDMETHODS:
From January 2007 through December 2009, 39 patients with HCC and liver cirrhosis were included in our liver transplantation program. We selected the 6 subjects who underwent 18-fluorodeoxyglucose PET/CT (18-FDG PET/CT) pre- and post-TACE.RESULTS:
The median SUV (standardized uptake value) in the lesions studied were 4 (range, 2.79-6.95) before TACE with a median post-TACE SUV of 0 (range, 0-4). Among patients whose post-TACE SUV decreased to <3, the percentage of necrosis after studying the hepatectomy was >80%.CONCLUSION:
Performance of an 18-FDG PET/CT before and after TACE and comparison of SUV in patients with HCC awaiting liver transplantation provided valuable information regarding the effectiveness of TACE.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Tomografía Computarizada por Rayos X
/
Trasplante de Hígado
/
Quimioembolización Terapéutica
/
Carcinoma Hepatocelular
/
Radiofármacos
/
Fluorodesoxiglucosa F18
/
Tomografía de Emisión de Positrones
/
Neoplasias Hepáticas
Tipo de estudio:
Prognostic_studies
País/Región como asunto:
Europa
Idioma:
En
Revista:
Transplant Proc
Año:
2011
Tipo del documento:
Article