Successful treatment of necrotizing fasciitis in an upper extremity caused by Clostridium perfringens after bone marrow transplantation.
Intern Med
; 50(19): 2213-7, 2011.
Article
en En
| MEDLINE
| ID: mdl-21963743
ABSTRACT
We report a 47-year-old man with acute leukemia who survived a severe case of necrotizing fasciitis caused by Clostridium perfringens involving his right upper extremity. On day 5 after stem cell transplantation, progressive local tissue necrosis led to septicemia and disseminated intravascular coagulation. Early diagnosis and prompt initiation of appropriate therapy, including surgical debridement and broad-spectrum antibiotics, were crucial. A recombinant thrombomodulin might have not only resolved the coagulation problem but also prevented multiple organ failure associated with the systemic inflammatory response.
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Base de datos:
MEDLINE
Asunto principal:
Trasplante de Médula Ósea
/
Fascitis Necrotizante
/
Gangrena Gaseosa
Tipo de estudio:
Screening_studies
Idioma:
En
Revista:
Intern Med
Asunto de la revista:
MEDICINA INTERNA
Año:
2011
Tipo del documento:
Article