Preventable exposures associated with human cancers.
J Natl Cancer Inst
; 103(24): 1827-39, 2011 Dec 21.
Article
en En
| MEDLINE
| ID: mdl-22158127
ABSTRACT
Information on the causes of cancer at specific sites is important to cancer control planners, cancer researchers, cancer patients, and the general public. The International Agency for Research on Cancer (IARC) Monograph series, which has classified human carcinogens for more than 40 years, recently completed a review to provide up-to-date information on the cancer sites associated with more than 100 carcinogenic agents. Based on IARC's review, we listed the cancer sites associated with each agent and then rearranged this information to list the known and suspected causes of cancer at each site. We also summarized the rationale for classifications that were based on mechanistic data. This information, based on the forthcoming IARC Monographs Volume 100, offers insights into the current state-of-the-science of carcinogen identification. Use of mechanistic data to identify carcinogens is increasing, and epidemiological research is identifying additional carcinogens and cancer sites or confirming carcinogenic potential under conditions of lower exposure. Nevertheless, some common human cancers still have few (or no) identified causal agents.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Carcinógenos Ambientales
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Exposición a Riesgos Ambientales
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Neoplasias
Tipo de estudio:
Etiology_studies
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Prognostic_studies
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Risk_factors_studies
Idioma:
En
Revista:
J Natl Cancer Inst
Año:
2011
Tipo del documento:
Article