Hybrid models of the neuromusculoskeletal system improve subject-specificity.
Proc Inst Mech Eng H
; 226(2): 113-9, 2012 Feb.
Article
en En
| MEDLINE
| ID: mdl-22468463
ABSTRACT
Muscle-actuated simulations of pathological gait have the capacity to identify muscle impairments and compensatory strategies, but the lack of subject-specific solutions prevents the prescription of personalized therapies. Conversely, electromyographic-driven models are limited to muscles for which data are available but can capture the true neural drive initiated by an individual subject. In order to improve subject-specificity and enforce physiological constraints on muscle activity, we propose a hybrid strategy for the optimization of subject-specific muscle patterns that involves forward dynamic simulation of whole body movement coupled with electromyographic-driven models of muscle subsets. In this paper we apply the hybrid approach to an example of post-stroke gait and demonstrate its unique ability to account for the unusual muscle activation patterns and muscle properties in patients with neuromuscular impairments.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Transmisión Sináptica
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Músculo Esquelético
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Trastornos Neurológicos de la Marcha
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Articulaciones
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Modelos Biológicos
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Contracción Muscular
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Unión Neuromuscular
Tipo de estudio:
Diagnostic_studies
Idioma:
En
Revista:
Proc Inst Mech Eng H
Asunto de la revista:
ENGENHARIA BIOMEDICA
Año:
2012
Tipo del documento:
Article