Antimicrobial activity of some Clerodendrum species from Egypt.
Nat Prod Res
; 27(11): 1032-6, 2013.
Article
en En
| MEDLINE
| ID: mdl-22594542
ABSTRACT
Chloroformic and methanolic extracts of four Clerodendrum species cultivated in Egypt were screened for antimicrobial activities. Chloroformic extracts of the flowers of Clerodendrum chinense and Clerodendrum splendens were active against Plasmodium falciparum (IC50 < 10 µg mL(-1)). Chloroformic extracts of the stem and flowers of C. chinense were active against Trypanosoma cruzi (IC50 = 1.21 and 1.12 µg mL(-1), respectively) with marginal cytotoxicity. Chloroformic extracts of the leaves of C. chinense and C. splendens showed promising activities against T. cruzi (IC50 = 3.39 and 1.98 µg mL(-1), respectively) without cytotoxic effect on a human cell line. None of the selected plants showed significant activity against Gram-negative or Gram-positive bacteria or Candida albicans. Verbascoside, a phenyl propanoid glycoside isolated from the leaves of C. chinense, showed marginal activity against T. cruzi. Rengyolone, a cyclohexyl ethanoid isolated from the leaves of C. chinense, showed a broad but not specific activity against the tested organisms.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Extractos Vegetales
/
Clerodendrum
/
Antiinfecciosos
País/Región como asunto:
Africa
Idioma:
En
Revista:
Nat Prod Res
Año:
2013
Tipo del documento:
Article