Your browser doesn't support javascript.
loading
Decisional procalcitonin thresholds are not adapted to elderly patients admitted to the emergency room.
Chenevier-Gobeaux, Camille; Trabattoni, Eloise; Elfassy, Yaelle; Picard, Camille; Guérin, Sylvie; Borderie, Didier; Claessens, Yann-Erick.
Afiliación
  • Chenevier-Gobeaux C; Groupe hospitalier Cochin-Broca-Hôtel Dieu, APHP, Department of Biochemistry, Paris, France. camille.gobeaux@cch.aphp.fr
Biomarkers ; 17(5): 477-81, 2012 Aug.
Article en En | MEDLINE | ID: mdl-22607374
ABSTRACT
CONTEXT Diagnosis of sepsis in elderly is challenging.

OBJECTIVES:

We investigated whether procalcitonin concentrations in elderly differed from values for the general population.

METHODS:

Procalcitonin measurement was assessed prospectively in 307 apyretic patients ≥75 years visiting the emergency department.

RESULTS:

Median age was 86 years [IQR81-90] and 222 (72%) were female. Procalcitonin concentration was 0.057 µg/L [0.040-0.092]; 99th percentile was 0.661 µg/L. Patients with procalcitonin concentrations above decisional thresholds had lower glomerular filtration rate and higher C-reactive protein concentrations.

CONCLUSIONS:

Baseline procalcitonin levels are increased in elderly. Elevated values are common and associated to low-grade inflammation and lower eGFR.
Asunto(s)

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Precursores de Proteínas / Proteína C-Reactiva / Calcitonina / Servicio de Urgencia en Hospital / Tasa de Filtración Glomerular Tipo de estudio: Observational_studies Idioma: En Revista: Biomarkers Asunto de la revista: BIOQUIMICA Año: 2012 Tipo del documento: Article

Texto completo: 1 Base de datos: MEDLINE Asunto principal: Precursores de Proteínas / Proteína C-Reactiva / Calcitonina / Servicio de Urgencia en Hospital / Tasa de Filtración Glomerular Tipo de estudio: Observational_studies Idioma: En Revista: Biomarkers Asunto de la revista: BIOQUIMICA Año: 2012 Tipo del documento: Article