Fat grafting's past, present, and future: why adipose tissue is emerging as a critical link to the advancement of regenerative medicine.
Aesthet Surg J
; 32(7): 892-9, 2012 Sep.
Article
en En
| MEDLINE
| ID: mdl-22942117
ABSTRACT
Fat grafting is a common reconstructive and aesthetic procedure with extensive clinical applications. Recently, significant strides have been made in investigating the biology behind the success of this procedure. Surgeons and scientists alike have advanced this field by innovating fat graft harvesting and injection techniques, expanding the use of adipose tissue and its stem cell components, and broadening our understanding of the viability of fat grafting at the molecular and cellular levels. The objectives of this review are to (1) discuss the clinical applications of fat grafting, (2) describe the cellular biology of fat and the optimization of fat graft preparation, (3) illustrate the significance of adipose-derived stem cells and the potentiality of fat cells, (4) highlight the clinical uses of adipose-derived stem cells, and (5) explore the current and future frontiers of the study of fat grafting. Although collaborative knowledge has increased exponentially, many of the biological mechanisms behind fat grafting are still unknown. Plastic surgeons are in a unique position to pioneer both the scientific and clinical frontiers of fat grafting and to ultimately further this technology for the benefit of our patients.
Texto completo:
1
Base de datos:
MEDLINE
Asunto principal:
Tejido Adiposo
/
Procedimientos de Cirugía Plástica
/
Medicina Regenerativa
Idioma:
En
Revista:
Aesthet Surg J
Año:
2012
Tipo del documento:
Article