An efficient synthesis of 4&#945;- and 4ß-hydroxy- 7-dehydrocholesterol, biomarkers for patients with and animal models of the Smith-Lemli-Opitz syndrome.

Kawamoto, Hiroaki; Ohmori, Yuusuke; Maekawa, Masamitsu; Shimada, Miki; Mano, Nariyasu; Iida, Takashi

An efficient synthesis of 4α- and 4ß-hydroxy- 7-dehydrocholesterol, biomarkers for patients with and animal models of the Smith-Lemli-Opitz syndrome.

Kawamoto, Hiroaki; Ohmori, Yuusuke; Maekawa, Masamitsu; Shimada, Miki; Mano, Nariyasu; Iida, Takashi.

Afiliación

Kawamoto H; Department of Chemistry, College of Humanities & Sciences, Nihon University, Sakurajousui, Setagaya, Tokyo 156-8550, Japan.

Chem Phys Lipids ; 175-176: 73-8, 2013.

Article en En | MEDLINE | ID: mdl-23920082

Asunto(s)

Deshidrocolesteroles/síntesis química; Deshidrocolesteroles/metabolismo; Síndrome de Smith-Lemli-Opitz/metabolismo; Animales; Biomarcadores/química; Biomarcadores/metabolismo; Deshidrocolesteroles/química; Modelos Animales de Enfermedad; Humanos; Síndrome de Smith-Lemli-Opitz/inducido químicamente; Diclorhidrato de trans-1,4-Bis(2-clorobenzaminometil)ciclohexano

Palabras clave

4α-hydroxy-7-dehydrocholesterol; 4ß-hydroxy-7-dehydrocholesterol; 7-dehydrocholesterol; Biomarker; Oxysterol; SmithLemliOpitz syndrome

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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Síndrome de Smith-Lemli-Opitz / Deshidrocolesteroles Idioma: En Revista: Chem Phys Lipids Año: 2013 Tipo del documento: Article

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