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Powerful tumor cell growth-inhibiting activity of a synthetic derivative of atractyligenin: involvement of PI3K/Akt pathway and thioredoxin system.
Cotugno, Roberta; Gallotta, Dario; Piaz, Fabrizio Dal; Apicella, Ivana; De Falco, Sandro; Rosselli, Sergio; Bruno, Maurizio; Belisario, Maria Antonietta.
Afiliación
  • Cotugno R; Department of Pharmacy, University of Salerno, 84084 Fisciano, Salerno, Italy.
  • Gallotta D; Department of Pharmacy, University of Salerno, 84084 Fisciano, Salerno, Italy.
  • Piaz FD; Department of Pharmacy, University of Salerno, 84084 Fisciano, Salerno, Italy.
  • Apicella I; Angiogenesis Lab, Institute of Genetics and Biophysics "Adriano Buzzati-Traverso" CNR, 80131 Napoli, Italy.
  • De Falco S; Angiogenesis Lab, Institute of Genetics and Biophysics "Adriano Buzzati-Traverso" CNR, 80131 Napoli, Italy.
  • Rosselli S; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, 90128 Palermo, Italy.
  • Bruno M; Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, University of Palermo, 90128 Palermo, Italy.
  • Belisario MA; Department of Pharmacy, University of Salerno, 84084 Fisciano, Salerno, Italy. Electronic address: mabelisario@unisa.it.
Biochim Biophys Acta ; 1840(3): 1135-44, 2014 Mar.
Article en En | MEDLINE | ID: mdl-24321480
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Atractilósido / Tiorredoxinas / Apoptosis / Fosfatidilinositol 3-Quinasas / Diterpenos de Tipo Kaurano / Proliferación Celular / Proteínas Proto-Oncogénicas c-akt / Antineoplásicos Idioma: En Revista: Biochim Biophys Acta Año: 2014 Tipo del documento: Article
Texto completo
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Texto completo: 1 Base de datos: MEDLINE Asunto principal: Atractilósido / Tiorredoxinas / Apoptosis / Fosfatidilinositol 3-Quinasas / Diterpenos de Tipo Kaurano / Proliferación Celular / Proteínas Proto-Oncogénicas c-akt / Antineoplásicos Idioma: En Revista: Biochim Biophys Acta Año: 2014 Tipo del documento: Article